Indications for: ZORYVE
Plaque psoriasis, including intertriginous areas.
Apply to the affected area(s) once daily; rub in completely.
<12yrs: not established.
Moderate to severe liver impairment (Child-Pugh B or C).
Not for oral, ophthalmic, or intravaginal use. Labor & delivery: not recommended. Pregnancy. Nursing mothers: avoid direct infant exposure.
Phosphodiesterase 4 (PDE4) inhibitor.
May be potentiated by systemic CYP3A4 inhibitors, dual CYP3A4/CYP1A2 inhibitors (eg, erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine), oral contraceptives containing gestodene + ethinyl estradiol; consider risks vs benefits prior to concomitant use.
Diarrhea, headache, insomnia, application site pain, upper respiratory tract infections, urinary tract infections.
Generic Drug Availability: