Emerging Treatments in HIV

Feature Article

Once-Daily Raltegravir Safe, Effective for Initial HIV Treatment

Once-Daily Raltegravir Safe, Effective for Initial HIV Treatment

Once-daily regimens have been shown to improve adherence to treatment with no adverse effect on outcomes in patients with HIV.

Latest News

Lamivudine/Tenofovir Disoproxil Approved for the Treatment of HIV-1 Infection

Lamivudine/Tenofovir Disoproxil Approved for the Treatment of HIV-1 Infection

The FDA has approved Temixys tablets for use in combination with other antiretroviral agents for the treatment of HIV-1 infection in patients weighing ≥35kg.

New Single-Vial Formulation of Tesamorelin Approved to Treat Excess HIV-Related VAT

New Single-Vial Formulation of Tesamorelin Approved to Treat Excess HIV-Related VAT

The new "F4" formulation is 4 times more concentrated than the version currently available on the market.

Fofomycin Injection: New Drug Application for Treatment of Complicated UTI

Fofomycin Injection: New Drug Application for Treatment of Complicated UTI

Contepo, an investigational epoxide intravenous (IV) antibiotic, has broad spectrum activity against Gram-negative and Gram-positive pathogens, including multi-drug resistant strains such as ESBL-producing Enterobacteriaceae.

TOL-463 Effective for Bacterial Vaginosis and Vulvovaginal Candidiasis

TOL-463 Effective for Bacterial Vaginosis and Vulvovaginal Candidiasis

TOL-463, particularly in vaginal insert form, is effective and safe in treating bacterial vaginosis and vulvovaginal candidiasis.

Ampicillin Plus Ceftriaxone: An Effective Alternative for E faecalis Infective Endocarditis

Ampicillin Plus Ceftriaxone: An Effective Alternative for E faecalis Infective Endocarditis

Ampicillin plus ceftriaxone was an effective treatment for penicillin-susceptible Enterococcus faecalis infective endocarditis compared with ampicillin plus gentamicin.

Continuous Antibiotic Infusion via Elastomeric Pumps Safe and Effective in Outpatients

Continuous Antibiotic Infusion via Elastomeric Pumps Safe and Effective in Outpatients

Treating outpatients with continuous infusions of flucloxacillin, cefepime, vancomycin, and piperacillin/tazobactam using elastomeric pumps was effective and safe.

Could Zika Virus Be a Potential Treatment for Neuroblastoma?

Could Zika Virus Be a Potential Treatment for Neuroblastoma?

Even with intensive therapy, survival among neuroblastoma patients is poor, indicating a need for alternative treatments.

Zemdri Now Available for the Treatment of Complicated UTI, Pyelonephritis

Zemdri Now Available for the Treatment of Complicated UTI, Pyelonephritis

Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

TPOXX Approved for the Treatment of Human Smallpox Disease

TPOXX Approved for the Treatment of Human Smallpox Disease

The approval was supported by findings from 12 clinical trials of TPOXX with more than 700 healthy volunteers that showed no drug-related serious adverse events.

Novel Antiretroviral Therapy Trogarzo Now Available to Treat HIV-1

Novel Antiretroviral Therapy Trogarzo Now Available to Treat HIV-1

The approval of Trogarzo was supported by a clinical trial (N=40) of heavily treatment-experienced adults with multidrug resistant HIV-1 infection who continued to have high levels of HIV RNA in their blood despite antiretroviral therapy.

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