HIV/AIDS

Glecaprevir/Pibrentasvir Highly Efficacious for HCV/HIV Coinfection

Glecaprevir/Pibrentasvir Highly Efficacious for HCV/HIV Coinfection

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Study results support the indication of glecaprevir/pibrentasvir as the first 8-week pangenotypic treatment option for HCV/HIV-1 coinfected patients without cirrhosis.

How San Francisco Is Tackling the HIV/HCV and Opioid Epidemics

How San Francisco Is Tackling the HIV/HCV and Opioid Epidemics

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Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.

Novel Digital ELISA May Detect, Quantify Low HIV p24 Concentrations in CSF

Novel Digital ELISA May Detect, Quantify Low HIV p24 Concentrations in CSF

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More comprehensive research will be needed to further investigate cerebrospinal fluid p24 by high-sensitivity assay as a marker for neurocognitive impairment during poorly controlled HIV and as a marker for HIV central nervous system reactivation during latency reversal therapy.

Generic HIV Medicines: Boon or Bust?

Generic HIV Medicines: Boon or Bust?

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Generic antiretroviral agents have had a dramatic effect on outcomes in developing nations, and their availability in developed countries is rapidly expanding as more brand-name drugs are coming off patent. But unique challenges surrounding their use remain.

Age, Exposure to Antiretrovirals Affect Diabetes Risk in HIV

Age, Exposure to Antiretrovirals Affect Diabetes Risk in HIV

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Interventions for diabetes prevention and management may be needed to reduce the risk for diabetes in patients with HIV.

About Half of Pregnant Women With HIV Have C-Sections

About Half of Pregnant Women With HIV Have C-Sections

About half of pregnant women with HIV infection underwent cesarean delivery between 1998 and 2013.

Antifungal Combination Treatment for Cryptococcal Meningitis in HIV

Antifungal Combination Treatment for Cryptococcal Meningitis in HIV

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The absence of availability of amphotericin B or in conditions in which amphotericin B cannot be administered safely, the oral combination of fluconazole plus flucytosine provides an effective and sustainable alternative.

Findings Support Nonavalent HPV Vaccine Use in Women With HIV

Findings Support Nonavalent HPV Vaccine Use in Women With HIV

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The HR-HPV types covered by the nonavalent HPV vaccine had similar clearance rates to HR-HPV types not included, and women infected with multiple anogenital HR-HPV types had lower rates of clearance than women infected with only 1 type.

HIV-1 Susceptibility Increases in Late Pregnancy and Postpartum Periods

HIV-1 Susceptibility Increases in Late Pregnancy and Postpartum Periods

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Researchers assessed the differential risk of acquiring HIV-1 infection across reproductive stages by calculating per-coital-act risk for each stage and comparing with nonpregnant times.

Single-Tablet HIV Regimen Improves Retention in Care and Virologic Suppression

Single-Tablet HIV Regimen Improves Retention in Care and Virologic Suppression

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Investigators assessed adherence to antiretroviral therapy, retention in care, and virologic outcomes in patients receiving once-daily single-tablet and multiple-tablet antiretroviral therapy regimens.

Effects of Peer Navigation Intervention on HIV Viral Suppression After Release From Jail

Effects of Peer Navigation Intervention on HIV Viral Suppression After Release From Jail

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The effects of a peer navigation intervention on HIV viral suppression in previously incarcerated individuals were examined.

Tenofovir Alafenamide Plus Emtricitabine Safely and Effectively Treats HIV-1

Tenofovir Alafenamide Plus Emtricitabine Safely and Effectively Treats HIV-1

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A head-to-head comparison was made between HIV-1 treatment regimens containing tenofovir alafenamide plus emtricitabine with those containing abacavir plus lamivudine.

Text Messaging Interventions Do Not Improve HIV Outcomes

Text Messaging Interventions Do Not Improve HIV Outcomes

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Text messaging may be a promising strategy for support and engagement in HIV care.

Emerging Technologies to Manage Antiretroviral Therapy Adherence

Emerging Technologies to Manage Antiretroviral Therapy Adherence

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The rapidly developing landscape of antiretroviral therapy adherence monitoring has great potential for clinical application, but cost-effectiveness and feasibility studies are needed to define the appropriate roles for these new technologies.

Worse Cognitive Outcomes Associated With CMV Antibodies Following ART for HIV

Worse Cognitive Outcomes Associated With CMV Antibodies Following ART for HIV

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Investigators sought to determine the association between antiretroviral therapy and cytomegalovirus infection in individuals with HIV, as well as the potential impact of both on neurocognitive performance.

Effectiveness of Daily vs Thrice-Weekly Tuberculosis Regimens in HIV Patients

Effectiveness of Daily vs Thrice-Weekly Tuberculosis Regimens in HIV Patients

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HIV-positive patients with pulmonary tuberculosis benefited from daily antituberculosis therapy in terms of effectiveness and rifampicin resistance.

Increased Risk for Abdominal Obesity Found in People Living With HIV

Increased Risk for Abdominal Obesity Found in People Living With HIV

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The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.

Menopause Contributes to Higher Symptom Burden in HIV

Menopause Contributes to Higher Symptom Burden in HIV

Certain HIV symptoms, especially fatigue, muscle aches, may be worsened with menopause.

FDA Approves Combination Treatment Symfi for HIV-1 Infection

FDA Approves Combination Treatment Symfi for HIV-1 Infection

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Symfi contains the same triple combination ingredients found in the recently approved and launched Symfi Lo but with a 600mg dose of efavirenz vs 400mg seen in Symfi Lo.

HIV Incidence Down in All Except Men Who Have Sex With Men

HIV Incidence Down in All Except Men Who Have Sex With Men

Access to prevention methods, such as condoms and preexposure prophylaxis, is needed, particularly among MSM of color and young MSM.

Rising Incidence of Diabetes in Adults With HIV on Antiretroviral Therapy

Rising Incidence of Diabetes in Adults With HIV on Antiretroviral Therapy

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More research is needed to better capture the interplay between prediabetes/diabetes and antiretroviral therapy in people with HIV.

HIV incidence has decreased overall, but remains higher among minority men who have sex with men

Overall HIV incidence in the United States has decreased in all high-risk transmission groups except for minority men who have sex with men.

Promoting Consistent HIV Testing Among Young Black MSM, Transgender Women Critical

Promoting Consistent HIV Testing Among Young Black MSM, Transgender Women Critical

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Connecting young Black MSM and transgender women to the best test option, given preferences for specific characteristics, may support more and more consistent HIV testing.

Adverse Pregnancy Outcomes With Isoniazid Preventive Therapy in HIV

Adverse Pregnancy Outcomes With Isoniazid Preventive Therapy in HIV

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Findings from this phase 4 study call for a re-evaluation of the current WHO and CDC guidelines of isoniazid preventive therapy for the prevention of tuberculosis in pregnant women with HIV.

High Use and Adherence Seen With Dapivirine Vaginal Ring for HIV Prevention

High Use and Adherence Seen With Dapivirine Vaginal Ring for HIV Prevention

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Interim results from this open-label extension trial of the dapivirine ring demonstrate high uptake and adherence, and HIV-1 incidence has been half of the expected rate.

Prevalence of HPV16 High Among HIV-Positive Men Having Sex With Men

Prevalence of HPV16 High Among HIV-Positive Men Having Sex With Men

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Study confirms HPV16 as an important determinant of high-grade lesions and supports its place as a priority for anal cancer prevention.

Single Tablet HIV Regimen Noninferior to Abacavir-Containing Regimen

Single Tablet HIV Regimen Noninferior to Abacavir-Containing Regimen

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A phase 3 study evaluating HIV patients who switched to treatment with Biktarvy found this combination therapy to be statistically noninferior to a regimen containing abacavir,

High Concentrations of Key Vaginal Bacteria May Increase Risk for HIV Acquisition

High Concentrations of Key Vaginal Bacteria May Increase Risk for HIV Acquisition

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Study evaluated the association between the concentrations of specific vaginal bacteria and increased risk for HIV acquisition in African women.

Intravenous Drug Approved for Multidrug-Resistant HIV Infection

Intravenous Drug Approved for Multidrug-Resistant HIV Infection

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The FDA has approved Trogarzo for the treatment of adults with HIV whose infections are multidrug-resistant.

Early diagnosis of HIV infection through analysis of oral fluid [Pre-Clinical]

A novel method - Antibody Detection by Agglutination-PCR (ADAP) - was developed to diagnose HIV in oral fluid samples. ADAP is both highly sensitive and highly specific and may allow noninvasive early diagnosis of HIV in population-based screening efforts.

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