HIV/AIDS

Risk Prediction Scores Aid Management of Chronic Kidney Disease in HIV

Risk Prediction Scores Aid Management of Chronic Kidney Disease in HIV

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Investigators sought to assess the effectiveness of tools to predict the risk of chronic kidney disease in individuals with HIV.

Assessment of Chronic Opioid Therapy in People Living With HIV

Assessment of Chronic Opioid Therapy in People Living With HIV

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Appropriate monitoring and implementation of guidelines for opioid therapy is lacking in patients living with HIV.

Recognizing Precipitators of Virologic Failure in Youth With HIV

Recognizing Precipitators of Virologic Failure in Youth With HIV

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Researchers assessed factors contributing to virologic failure in youth with perinatally acquired HIV infection receiving highly active antiretroviral therapy.

Multilevel Interventions Needed to Improve Barriers to PrEP

Multilevel Interventions Needed to Improve Barriers to PrEP

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The final review included 47 articles that fell under 1 of the following categories: primary data on cognitive variables of providers; data on cognitive variables and perspectives of individuals at risk for HIV infection; literature on PrEP implementation; and case studies of PrEP demonstration and implementation projects.

Social Network Support Decreases Risk for HIV Seroconversion in Black MSM

Social Network Support Decreases Risk for HIV Seroconversion in Black MSM

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The increased presence of social network support may decrease the risk for HIV seroconversion in black MSM.

Higher Rate of Mother-to-Child Transmission Among Women With Perinatal HIV

Higher Rate of Mother-to-Child Transmission Among Women With Perinatal HIV

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Although rates of mother-to-child transmission of HIV have decreased as a result of effective treatments and protective delivery and feeding practices, transmission does persist.

ART Simplification Does Not Affect Systemic Inflammation in Virologically Suppressed HIV

ART Simplification Does Not Affect Systemic Inflammation in Virologically Suppressed HIV

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Simplification to atazanavir/ritonavir plus lamivudine as a maintenance therapy has the same effect on markers of systemic inflammation biomarkers as triple therapy.

Long-Term Viral Suppression May Decrease Cancer Risk in HIV+ Individuals

Long-Term Viral Suppression May Decrease Cancer Risk in HIV+ Individuals

Antiretroviral therapy resulting in long-term viral suppression of HIV may contribute to cancer prevention.

Closer Monitoring Recommended for Older Patients Treated With Dolutegravir for HIV

Closer Monitoring Recommended for Older Patients Treated With Dolutegravir for HIV

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The maximum concentration of the integrase inhibitor dolutegravir was significantly higher in older people living with HIV.

Prezcobix Not Recommended During Pregnancy, According to Updated Labeling

Prezcobix Not Recommended During Pregnancy, According to Updated Labeling

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The labeling now states that Prezcobix is not recommended for use in pregnant women due to substantially lower exposures of the active ingredients, darunavir and cobicistat, during pregnancy.

Cancer Treatment Disparities in Elderly HIV-Infected Americans Warrant Attention

Cancer Treatment Disparities in Elderly HIV-Infected Americans Warrant Attention

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Cancer treatment rates for HIV-infected seniors were lowest among the younger subset of patients, who would likely benefit most from treatment in terms of life expectancy.

Cumulative Ritonavir-Boosted Darunavir Use May Be Associated With Increased CVD Risk

Cumulative Ritonavir-Boosted Darunavir Use May Be Associated With Increased CVD Risk

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An increased risk for cardiovascular disease with ritonavir-boosted darunavir regimens for HIV was identified in a prospective multicenter study.

Psychosocial Interventions in HIV: How Best to Support HIV-Positive Patients

Psychosocial Interventions in HIV: How Best to Support HIV-Positive Patients

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Mental health professionals supporting patients living with HIV need to make space for their patients to process the emotional effect of their diagnosis, but not to make assumptions about what it means to them.

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

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A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.

Bilirubin Levels May Be Predictive of Cardiovascular Disease in HIV

Bilirubin Levels May Be Predictive of Cardiovascular Disease in HIV

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Bilirubin appeared to be inversely associated with cardiovascular disease in individuals with HIV enrolled in the Veterans Aging Cohort Study.

Continuous Medicaid Coverage Essential for People Living With HIV

Continuous Medicaid Coverage Essential for People Living With HIV

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Implementing initiatives to maintain Medicaid enrollment and to expedite Medicaid reenrollment and having alternate resources available in gaps are important to ensure continuous antiretroviral therapy to optimize HIV outcomes.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals Infected With HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals Infected With HIV

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In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

HIV Self-Testing Increases Testing Frequency in High-Risk MSM

HIV Self-Testing Increases Testing Frequency in High-Risk MSM

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Research is needed to understand how to prioritize supplementation and reach new testers, to educate men about the limitations of the current self-test, and to invest in the development and evaluation of self-tests able to detect early infection.

Fungal Infections of the CNS: Diagnostic and Treatment Approaches

Fungal Infections of the CNS: Diagnostic and Treatment Approaches

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While immunocompromised patients are the most susceptible to CNS fungal infections, they can also occur in immunocompetent patients undergoing invasive procedures such as neurosurgery and in patients exposed to contaminated devices or drugs.

Short Cycle ART Noninferior to Continuous Therapy in Youth With HIV

Short Cycle ART Noninferior to Continuous Therapy in Youth With HIV

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Standard-dose efavirenz-based short cycle therapy is a viable option for virologically suppressed HIV-1-infected young people receiving first-line antiretroviral therapy with 3-monthly viral load monitoring.

Increasing Incidence of Syphilis in People With HIV

Increasing Incidence of Syphilis in People With HIV

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Steady increases in the syphilis incidence rate occurred through 2015, particularly among people with HIV who are younger, non-Hispanic/Latino, and are men who have sex with men.

FDA: Possible Risk of Neural Tube Birth Defects With Certain Antiretroviral Agents

FDA: Possible Risk of Neural Tube Birth Defects With Certain Antiretroviral Agents

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The FDA has received reports of serious neural tube birth defects in babies born to women who received dolutegravir for HIV.

Truvada Approved for HIV-1 Pre-Exposure Prophylaxis in At-Risk Adolescents

Truvada Approved for HIV-1 Pre-Exposure Prophylaxis in At-Risk Adolescents

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The use of Truvada for PrEP in the adolescent population was based on a single-arm, open-label clinical study (ATN113) among 67 HIV-1 negative young men (aged 15 to 17 years) who have sex with men (YMSM).

Importance of PrEP for People Involved in Criminal Justice Systems

Importance of PrEP for People Involved in Criminal Justice Systems

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Important strategies to consider for people involved in the criminal justice systems include linkage to antiretroviral therapy for those who are HIV positive and linkage to PrEP postrelease and/or beginning PrEP before people are released so they build up adherence.

FDA Approves Epoetin Alfa Biosimilar Retacrit

FDA Approves Epoetin Alfa Biosimilar Retacrit

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The approval of Retacrit was based on a review of evidence that included human pharmacokinetic/pharmacodynamic data and clinical immunogenicity data which demonstrated a high degree of similarity between Retacrit and its reference product.

PD-1 Inhibitors Safe, Effective in Patients With HIV and Non-Small Cell Lung Cancer

PD-1 Inhibitors Safe, Effective in Patients With HIV and Non-Small Cell Lung Cancer

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Nivolumab and pembrolizumab can be safe and effective for patients with NSCLC and HIV.

Women, HIV, and the Criminal Justice System: Prison Health Is Public Health

Women, HIV, and the Criminal Justice System: Prison Health Is Public Health

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Jaimie P. Meyer, MD, from the Yale School of Medicine, discusses her work on identifying opportunities to reduce risk for HIV transmission, particularly in women involved in the criminal justice system.

Cancer Incidences and Burden Expected to Shift in HIV

Cancer Incidences and Burden Expected to Shift in HIV

The cancer burden among persons living with HIV is projected to shift by 2030.

Risk of Adverse Birth Outcomes in Women With HIV Using Tenofovir-Emtricitabine

Risk of Adverse Birth Outcomes in Women With HIV Using Tenofovir-Emtricitabine

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The number of adverse birth outcomes was not higher with tenofovir, emtricitabine, and ritonavir-boosted lopinavir than with zidovudine, lamivudine, and ritonavir-boosted lopinavir or tenofovir, emtricitabine, and ritonavir-boosted atazanavir in HIV-infected women and their infants in the United States.

Eplerenone May Improve Cardiovascular Disease Risk in HIV

Eplerenone May Improve Cardiovascular Disease Risk in HIV

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Researchers investigated effects of eplerenone on insulin sensitivity, inflammatory indices, and other metabolic parameters in HIV.

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