HIV

Worse Cognitive and Motor Outcomes for HIV-Infected, HIV-Exposed Children

Worse Cognitive and Motor Outcomes for HIV-Infected, HIV-Exposed Children

Study found that both HIV+ and HIV-exposed but uninfected children had worse developmental outcomes compared with HIV-unexposed and uninfected children.

Prognostic Value of Plasma JC Virus-DNA in Progressive Multifocal Leukoencephalopathy

Prognostic Value of Plasma JC Virus-DNA in Progressive Multifocal Leukoencephalopathy

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Polyomavirus JC-DNA assessment in plasma samples might complement progressive multifocal leukoencephalopathy diagnosis, especially when cerebrospinal fluid (CSF) is unavailable or polyomavirus JC-DNA is not detectable in CSF.

Three-Drug Regimen for HIV Treatment in Adults, Pediatrics Approved

Three-Drug Regimen for HIV Treatment in Adults, Pediatrics Approved

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The FDA has approved Symfi Lo as a complete regimen for the treatment of HIV-1 infection in adult and pediatric patients.

ED Screening Using Antigen-Antibody Tests Identify Previously Undiagnosed HIV

ED Screening Using Antigen-Antibody Tests Identify Previously Undiagnosed HIV

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A study found that nontargeted screening using antigen-antibody tests identified previously undiagnosed HIV infection at a rate that exceeded the CDC screening threshold by severalfold.

Rilpivirine Dosing Information Updated for Pregnant Women With HIV

Rilpivirine Dosing Information Updated for Pregnant Women With HIV

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The prescribing information for Edurant has been updated to include dosing recommendations for pregnant women.

No Difference in Aging-Related Brain Changes in Patients With Suppressed HIV

No Difference in Aging-Related Brain Changes in Patients With Suppressed HIV

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No differences in brain structure or cognitive function were seen over the course of 2 years compared with closely matched HIV-negative control patients.

FDA: Drug Interactions Section Updated for Prezcobix

FDA: Drug Interactions Section Updated for Prezcobix

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The FDA has updated labeling for Prezcobix with new drug interactions data.

Mortality in HIV-Infected Children Predicted by Urine TB Lipoarabinomannan

Mortality in HIV-Infected Children Predicted by Urine TB Lipoarabinomannan

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Benefits of urine lipoarabinomannan include its rapid point-of-care platform, low cost, and readily accessible sample type.

CDC: HIV Testing Low Among US Adults

CDC: HIV Testing Low Among US Adults

Almost 40% of women and more than 50% of men aged 15 to 44 years had never been tested for HIV between 2011 and 2015.

Cancer Risk Increased for Older Patients Living With HIV

Cancer Risk Increased for Older Patients Living With HIV

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Investigators assessed the impact of age and length of time with HIV infection on risk for developing cancer.

Lung Cancer Treatment May Successfully Deplete HIV Reservoir

Lung Cancer Treatment May Successfully Deplete HIV Reservoir

HIV reservoir may be successfully depleted with nivolumab treatment for non-small-cell lung cancer.

HIV exposure and infection affect neurodevelopmental outcomes in young children

Children less than 8 years old infected with HIV and children who were HIV exposed-but-uninfected had poorer neurodevelopmental outcomes compared to unexposed children.

Survival Outcomes Improved With Concurrent Treatment for Multidrug-Resistant TB and HIV

Survival Outcomes Improved With Concurrent Treatment for Multidrug-Resistant TB and HIV

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Co-infected participants treated concurrently for multidrug-resistant tuberculosis and HIV had similar survival to participants with multidrug-resistant tuberculosis alone.

FDA Updates Labeling for Dolutegravir/Rilpivirine

FDA Updates Labeling for Dolutegravir/Rilpivirine

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The FDA has updated labeling for Juluca to correct dosing separation between Juluca and oral calcium and iron supplements.

HIV Care Continuum: Effects of Depression, Alcohol Use on Early Retention in ART

HIV Care Continuum: Effects of Depression, Alcohol Use on Early Retention in ART

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Mental health at the time of antiretroviral therapy initiation indicates early effect on the HIV care continuum.

One-Time Routine HIV Screening at Age 25 Optimal With No Risk Factors

One-Time Routine HIV Screening at Age 25 Optimal With No Risk Factors

Using adult quality-of-life weights for adolescents and young adults increased the incremental cost-effectiveness ratios of screen at 25 compared to screen at age 30 to $115,900/quality-adjusted life-year.

Over one-third of U.S. HIV patients are not vaccinated against hepatitis B

One third of HIV patients in the United States (U.S.) remain unvaccinated against hepatitis B. Of HIV patients who were candidates for hepatitis B vaccination, only 1 in 10 were vaccinated within 1 year of continuing care for HIV.

Psychosocial Risk Factors in Adolescence Linked to HIV Vulnerability in Adulthood

Psychosocial Risk Factors in Adolescence Linked to HIV Vulnerability in Adulthood

High-frequency psychosocial risk factors during adolescence have a lasting effect on the likelihood of engaging in HIV risk behaviors in adulthood.

Vagus Nerve Stimulation May Improve HIV-Associated Depression

Vagus Nerve Stimulation May Improve HIV-Associated Depression

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Transcutaneous vagus nerve stimulation could provide a safe alternative treatment in HIV-depression by targeting both depression and other comorbidities that can burden people living with HIV.

Primary Care: Next Frontier in Managing HIV Care

Primary Care: Next Frontier in Managing HIV Care

Primary care providers will play an important role in preventing the next wave of HIV infections.

Hepatitis B Vaccination Prevalence Low in Patients With HIV

Hepatitis B Vaccination Prevalence Low in Patients With HIV

More than one-third of adult US HIV patients miss opportunities to initiate hepatitis B vaccination.

Value of Confirmatory Testing of Early Infant Diagnosis for HIV

Value of Confirmatory Testing of Early Infant Diagnosis for HIV

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Confirmatory testing is valuable and cost-effective for assessing HIV in infants considering false-positive rates of more than 10% when using nucleic acid amplification testing.

More Evidence That Early Diagnosis of HIV and Early ART Are Beneficial

More Evidence That Early Diagnosis of HIV and Early ART Are Beneficial

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Since early ART limits HIV reservoir size and preserves central memory CD4 cells, patients treated from primary HIV infection with low HIV-DNA levels might be good candidates for future HIV cure strategies.

Low Adherence to Guidelines for Cardiovascular Care in HIV

Low Adherence to Guidelines for Cardiovascular Care in HIV

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A new study sought to qualify the adherence to evidence-based cardiovascular care guidelines for patients living with HIV.

Treatment Regimens and Recommendations for HIV/HCV Coinfection

Treatment Regimens and Recommendations for HIV/HCV Coinfection

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Experts discuss the management of drug-drug interactions in patients receiving treatment for HIV and HCV coinfection.

Can We Prevent HIV and STIs Through School Programs?

Can We Prevent HIV and STIs Through School Programs?

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Although a positive impact on behavior change has been reported following the implementation of curriculum-based programs, there is a lack of clear evidence that school-based educational interventions directly prevent HIV/STIs.

Breastfeeding Mediates Pneumonia Outcomes in HIV-Exposed Children

Breastfeeding Mediates Pneumonia Outcomes in HIV-Exposed Children

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Investigators evaluated pneumonia outcomes and HIV exposure with birth weight status, malnutrition, breast feeding, in utero exposure to combination antiretroviral therapy, or the severity of pneumonia.

How HIV Affects Cervical Cancer Risk and Outcomes

How HIV Affects Cervical Cancer Risk and Outcomes

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Women with HIV have an increased risk for persistent HPV infection, which frequently progresses to cervical cancer, and they should be warned of their increased risk for HPV and cervical cancer and, when appropriate, advised to undergo HPV vaccination.

Acquired HIV Drug Resistance Unlikely With Immediate ART Initiation

Acquired HIV Drug Resistance Unlikely With Immediate ART Initiation

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In high-income countries, the need for second-line treatments due to the development of acquired drug resistance will increase only slightly under the new ART initiation guidelines.

HIV Neurocognitive Performance Not Associated With Recent Alcohol Intake

HIV Neurocognitive Performance Not Associated With Recent Alcohol Intake

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The only areas in which neurocognitive performance in the sample was significantly associated with alcohol use were visual memory/learning and attention.

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