Phase 1 Trial Shows Promising Results for Lenvervimab for HBV Treatment
Lenvervimab was well tolerated and reduced levels of HBsAg to below undetectable levels for up to 1 month in patients with chronic HBV infection.
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Infant Respiratory Syncytial Virus Increases Bronchiolitis, Pneumonia Risks
The development of respiratory syncytial virus (RSV) bronchiolitis in infants within the first 6 months of life was associated with increased odds of pneumonia, otitis media, and filling of antibiotic prescriptions in the second 6 months of life, according to study results published in Clinical Infectious Diseases. This was a population-based cohort study of infants…
Resistance-Guided Antimicrobial Therapy for Mycoplasma genitalium Infection
For infections with Mycoplasma genitalium, resistance-guided therapy using doxycycline followed by azithromycin or moxifloxacin led to high levels of microbiologic cure and low levels of de novo resistance, according to data published in Clinical Infectious Diseases. A total of 383 patients who attended Melbourne Sexual Health Centre in Australia between 2017 and 2018 with sexually…
Descovy for PrEP Continues to Be Noninferior to Truvada, According to 96 Week Data
Descovy demonstrated continued noninferiority to Truvada for HIV pre-exposure prophylaxis and statistically significant differences over Truvada for pre-specified secondary end points.
Pediatric Recipients of Liver Transplant Often Undervaccinated
Many pediatric liver transplant recipients are undervaccinated.
Crowd Diagnosis of STDs Frequently Sought Online
Crowd diagnosis of sexually transmitted diseases (STDs) is common online.
Conflict-Driven Migration Increases Hepatitis Burden as Production Costs Fall
Researchers of studies on the effect of conflict-driven migration on rates of hepatitis indicate that mass migration from high-burden countries has significantly increased the prevalence of both hepatitis C virus (HCV) and hepatitis B virus (HBV) infection in the host nation.
DAA Therapy Associated With Higher Survival in HCV-Related Comorbidities
Patients with hepatitis C virus (HCV) and comorbidities, including hepatocellular carcinoma (HCC), clinically significant portal hypertension, and cirrhosis were shown to have significantly higher survival rates when treatment included directly acting antiviral agent (DAA) therapy, according to the results of several studies presented at the American Association for the Study of Liver Diseases’ The Liver…
New EMR-Based Tools Improve Hepatitis Screening in Various Care Settings
New diagnostic tools used to identify hepatitis C virus (HCV) and hepatitis B virus (HBV) utilize simple questionnaires and emergency medical records (EMR) to alert physicians in both primary care and high-volume care settings about patients at risk for viral hepatitis infection or reactivation. The results of these studies were presented at the American Association…
Microbiome Alterations Vary With Infections, Disease State
Three studies investigated and assessed changes in the gut microbiome among recipients of liver transplant, patients with hepatitis C virus, and patients with primary sclerosing cholangitis.
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