Before the turn of the year, we predicted that the first supervised injection site would open in the United States. We revisit the debate over the efficacy and legality of these facilities and provide an update on where things stand.
Prednisone during the first month of ART for those with HIV leads to a lower incidence of tuberculosis-related immune reconstitution inflammatory syndrome.
Combination therapy of lamivudine plus dolutegravir has shown efficacy, safety, and tolerability in people with HIV-1 infection.
A new integrase inhibitors resistance pathway in HIV-2 infected patients has been identified rendering isolates that are highly resistant.
Among men who have HIV who also have sex with men, HPV-related biomarkers provide long-term risk stratification for anal precancers.
Although HIV diagnoses among Black women have declined since 2008, there are disparities between US-born and non-US-born Black women.
Depression is a common comorbidity in people living with HIV, with lifetime prevalence estimates ranging from 22% to 61%.
Early diagnosis of HIV is associated with higher viral loads compared to when individuals are diagnosed in later stages of the disease.
Findings show the safety of dapivirine use in early pregnancy and provide support for additional studies of the dapivirine ring at different gestational ages in order to confirm the safety of dapivirine ring use throughout pregnancy.
Researchers found substantial room for improvement in the delivery of substance use and mental health counseling and treatment and HIV/STD prevention counseling.
For people who inject drugs, recent incarceration is associated with considerable short-term increases in acquisition risk of HCV and HIV infection.
The absolute CD4/CD8 ratio is a more stable marker of immune recovery rates in HIV-infected patients beginning ART than absolute CD4+ T lymphocyte count.
Introducing certified health educator-driven routine opt-out rapid HIV screening and system-level modifications significantly increased HIV screening rates, rapid tests, and result receipt in youth.
For children with HIV, mitochondrial DNA mutations accumulate over time with long-term nucleoside reverse-transcriptase inhibitor exposure.
Patients with HIV who are initiating ART for the first time show a significant increase in fat and lean body mass during the first few years of treatment.
Higher fibroblast growth factor-23 concentrations are independently associated with incident frailty among HIV-infected and -uninfected men, particularly among blacks.
Results provide an evidence base for effective pediatric advance care planning in pediatric, hospital-based HIV clinics to achieve quality improvement.
Pre-exposure prophylaxis is a highly effective element of the combination prevention approach in men who have sex with men.
People of Hispanic ethnicity with HIV have an elevated risk for HPV-related cancers.
For patients with HIV, hepatitis C virus coinfection is a significant risk factor for mortality after initiating antiretroviral therapy.
Hispanic/Latina women with HIV infection receiving medical care face greater socioeconomic and language-related challenges than their male counterparts.
The study evaluated a cohort of 14 young black, men who have sex with men in Atlanta, Georgia, who had HIV seroconversion despite treatment with PrEP.
Chronic pain is a frequent comorbidity in people living with HIV, with a 2014 systematic review finding a 54% point prevalence.
An online intervention designed to mitigate sexual risk behaviors among young black MSM has demonstrated efficacy in short term risk reduction.
Dedicated resources are needed to optimize HIV care for people living with HIV while they are in prison and link them to care following release.
PLWHIV who have received treatment had lower whole-brain standardized uptake values compared to healthy controls with risk for CVD as the best predictor.
Dosing recommendations for lopinavir/ritonavir include larger doses for infants; this may still result in low drug concentrations for infants younger than 6 months of age receiving the liquid formulation.
Symptoms of depression and heavy alcohol use interact to lower the chances of achieving virologic suppression in people with HIV infection.
The “8.1 Pregnancy” and “12.3 Pharmacokinetics” sections have been updated with data showing no increase in the risk of overall major birth defects with 1st trimester exposure for rilpivirine.
Rapid PrEP implementation can substantially reduce HIV incidence at the population level in MSM during HIV epidemics.
Long-term PrEP is associated with enteric microbiome dysbiosis.
For patients with HIV, allogeneic hematopoietic stem cell transplant leads to a long-term reduction in the HIV reservoir.
In men with HIV, 1,25(OH)2D levels are associated with inflammation, suggesting that inflammation may lead to the increased comorbidity in this population.
A living donor liver transplant from a mother with HIV to her child who is HIV-negative was successful.
Pod-intravaginal rings appear to be safe and well tolerated for delivering different regimens of ART for pre-exposure HIV prophylaxis.
Although men who have sex with men account for approximately 2% of the population in the United States, they continue to be disproportionally affected by HIV infection.
Low adherence by females to the dapivirine vaginal ring may be caused by social harms by male partners.
Absolute CD4 cell count may predict disease progression and death in individuals coinfected with HIV and hepatitis C virus.
Supervised injection sites offer intravenous drug users sanitized needles to inject illicit drugs already in their possession. The goal, in part, is to reduce HIV transmission resulting from needle sharing. What are some pros and cons of these facilities?
Older adolescents initiating antiretroviral therapy have a high risk for loss to follow-up.