General Infectious Disease

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Typhoid Fever in US Children: Vaccination Low and Antimicrobial-Resistant Infections Common

By

Sweta Gupta

Investigators explored the implications of updated vaccination strategies for typhoid fever targeting younger at-risk children in the United States.

Alcaligenes faecalis: An Emerging Extensively Drug-Resistant Bacterium

By

Sweta Gupta

Retrospective analysis was conducted to assess the presence of A faecalis infection, extensively drug-resistant A faecalis infection, and the susceptibility of commonly used antibiotics for the treatment of A faecalis and XDR A faecalis.

LRINEC Tool May Be Effective to Rule Out Necrotizing Soft Tissue Infections in T2D

By

Colby Stong

The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) scoring system’s utility in diagnosing necrotizing soft tissue infections of the lower extremities in patients with diabetes was assessed.

Address Possible Security Lapses as Your Practice Returns to Normal

By

Tammy Worth

To accommodate patients remotely during the COVID-19 pandemic, practices may have expanded personnel access to protected health information and relied on devices that might be vulnerable to cyber attacks.

Glycemic Control May Reduce Infection Risk in Patients With Cirrhosis and Uncontrolled Diabetes Mellitus

By

Jessica Nye, PhD

Investigators evaluated the clinical impact of uncontrolled diabetes mellitus on infection and mortality in an inpatient population with advanced cirrhosis.

Antibiotics Noninferior to Appendectomy for Appendicitis Treatment

By

Bradley van Paridon

Investigators proposed antibiotic therapy as an alternative to surgery for the treatment of appendicitis.

Disinfectant Wipes Transfer C Difficile Spores

By

Bradley van Paridon

Study authors tested the effect of disinfectant wipes on spore loads and cross-contamination risk for Clostridioides difficile.

Miltefosine Effective for Cutaneous Leishmaniasis Therapy

By

Bradley van Paridon

Investigators assessed the efficacy of miltefosine in the treatment of cutaneous leishmaniasis and adverse events associated with its use.

Displacement of Commensal Skin Microbes Post Colorectal Surgery

By

Bradley van Paridon

Investigators characterized temporal and spatial variation in the skin microbiota of patients undergoing colorectal surgery and to determine if dysbiosis contributes to surgical site infections.

Disease Burden of Serious Infections Increased in Sjögren Syndrome

By

Rheumatology Advisor Contributing Writer

Study authors assessed the incidence, time-trends, and outcomes of serious infections in Sjögren syndrome.

Olanexidine Superior to Povidone-Iodine in Reducing Surgical Site Infection

By

Zahra Masoud

Study authors compared the effect of aqueous olanexidine and aqueous povidone-iodine on the incidence of surgical site infection following clean-contaminated surgery.

Infection Risk During Targeted and Biologic Therapies in Rheumatoid Arthritis and Psoriatic Arthritis

By

Tori Rodriguez, MA, LPC, AHC

An overview of the risk for infections during targeted and biological therapies in rheumatoid arthritis and psoriatic arthritis.

CREDIBLE-CR: Cefiderocol Effective for Serious Carbapenem-Resistant Gram-Negative Infections

By

Bradley van Paridon

Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.

Valacyclovir Effective at Reducing Vertical Cytomegalovirus Transmission

By

Bradley van Paridon

Study authors assessed the rate of vertical transmission of cytomegalovirus in pregnant women depending on with CMV infections are acquired periconceptionally or within the first trimester.

Long-Term Immune Response With Single-Dose, Inactivated Japanese Encephalitis Vaccine

By

Sweta Gupta

Study authors investigated the persistence of immune response with a single-dose of inactivated Japanese encephalitis vaccine and the interchangeability with a live-attenuated vaccine in healthy children aged 1 to 15 years.

No Increased Risk for Psychiatric Disorders in Individuals With Lyme Disease

By

Rose Reeb

In order to investigate the risk of psychiatric disease, the percentage of psychiatric hospital inpatient and outpatient contacts, and the receipt of prescribed psychiatric medications among patients in Denmark with Lyme neuroborreliosis was compared with individuals in a matched comparison cohort.

Delayed Meropenem-Vaborbactam for Gram-Negative Infections Increases Negative Clinical Outcomes

By

Marissa Purdy

Investigators evaluated the relationship between delay of meropenem and vaborbactam therapy in patients with gram-negative bacterial infections and negative clinical outcomes.

Acute Kidney Injury with Vancomycin, Antipseudomonal Combination Therapy

By

Bradley van Paridon

Investigators assessed the incidence of acute kidney injury in patients requiring vancomycin and antipseudomonal agents, particularly comparing piperacillin-tazobactam vs cefepime in combination with vancomycin.

Lower Measles and Mumps Seroprotection in Cancer Patients

By

Zahra Masoud

Study authors measured seroprevalence of measles and mumps among cancer patients and compared seroprevalence based on demographic, disease, and treatment subgroups.

Antibiotic Use With Immune Checkpoint Inhibitors Associated With Poor Outcomes in Cancer Patients

By

Bradley van Paridon

Study authors sought to determine the effect of antibiotic use and immune checkpoint inhibitors on overall survival, profession-free survival, response rate, and progressive disease rate in cancer patients.