GI.1 Virus Lot 001-09NV Aids Norovirus Vaccine Development
The Norwalk GI.1 virus Lot 001-09NV may be a useful challenge strain for future norovirus vaccine development.
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Lower Education, Hepatitis C Co-Infection Linked to Earlier Menopause in HIV
In women with HIV, lower education and hepatitis C co-infection are independently associated with the onset of menopause before age 45 years.
Specific Antibiotic Use Associated With Rheumatoid Arthritis Diagnosis, Flare Risk
Researchers aimed to determine the association of antibiotic usage and rheumatoid arthritis diagnosis and flares.
Controlling Antibiotic Adverse Drug Reactions in Cystic Fibrosis
The majority of patients with cystic fibrosis experience at least 1 antibiotic adverse drug reaction.
Cefiderocol Approved for Complicated UTI in Patients With Limited or No Alternative Treatment Options
The FDA has approved Fetroja for the treatment of complicated urinary tract infections.
M72/AS01 Tuberculosis Vaccine Remains Efficacious After 3 years
The M72/AS01 vaccine shows efficacy against pulmonary tuberculosis (TB) at 3 years in patients with Mycobacterium tuberculosis infection.
Ethnic Disparities in Preexposure Prophylaxis Among Men Having Sex With Men
According to the United States Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report, preliminary data from 2017 show that gay, bisexual, and other men who have sex with men accounted for 67% of incident diagnoses of HIV.
Aztreonam/Avibactam Combination Therapy Granted QIDP, Fast Track Status for Antibiotic-Resistant Infections
The FDA has granted QIDP designation and Fast Track designation to ATM-AVI for treatment of complicated intra-abdominal infections and more.
Concomitant Stimulant, Quinolone Use May Increase Risk of Cardiac Symptoms
There appears to be an increased risk of cardiac symptoms, but not cardiac arrhythmias, in patients using stimulants and quinolone antibiotics concomitantly.
First Ebola Vaccine Approved by European Commission
The world’s first Ebola vaccine has been approved by the European Commission, and it was quickly prequalified by the World Health Organization.
Minimal Response to Entecavir/Peginterferon in Children With Immune-Tolerant Chronic HBV
Overall response rate to combination of entecavir and peginterferon was low in children with immune-tolerant chronic HBV infection and adverse side effects were common, indicating that this approach is of limited and unsatisfactory efficacy.
Maternal Factors Predictive for Fetal Cytomegalovirus Infection
Maternal viremia predicted fetal infection and neonatal outcome of infants of women with a primary cytomegalovirus infection during pregnancy.
Early Postoperative Infection Increases One-Year Infection, Mortality Risk
Patients with 30-day postoperative infection have an increased risk for long-term infection and mortality.
Syringe Exchange Program Has Positive Effect on HIV Diagnoses
Estimated 10,592 HIV diagnoses averted in Philadelphia, 1,891 diagnoses in Baltimore over 10 years
AHA: About One in Three With CVD Not Receiving Flu Shot
About one in three individuals with atherosclerotic cardiovascular disease (ASCVD) did not receive an influenza vaccination in the past year.
Phase 1 Trial Shows Promising Results for Lenvervimab for HBV Treatment
Lenvervimab was well tolerated and reduced levels of HBsAg to below undetectable levels for up to 1 month in patients with chronic HBV infection.
Infant Respiratory Syncytial Virus Increases Bronchiolitis, Pneumonia Risks
The development of respiratory syncytial virus (RSV) bronchiolitis in infants within the first 6 months of life was associated with increased odds of pneumonia, otitis media, and filling of antibiotic prescriptions in the second 6 months of life, according to study results published in Clinical Infectious Diseases. This was a population-based cohort study of infants…
Resistance-Guided Antimicrobial Therapy for Mycoplasma genitalium Infection
For infections with Mycoplasma genitalium, resistance-guided therapy using doxycycline followed by azithromycin or moxifloxacin led to high levels of microbiologic cure and low levels of de novo resistance, according to data published in Clinical Infectious Diseases. A total of 383 patients who attended Melbourne Sexual Health Centre in Australia between 2017 and 2018 with sexually…
Descovy for PrEP Continues to Be Noninferior to Truvada, According to 96 Week Data
Descovy demonstrated continued noninferiority to Truvada for HIV pre-exposure prophylaxis and statistically significant differences over Truvada for pre-specified secondary end points.
Pediatric Recipients of Liver Transplant Often Undervaccinated
Many pediatric liver transplant recipients are undervaccinated.
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