Antiretroviral Nonadherence, Unsuppressed Viral Load Prevalent Across Adolescence
The prevalence of nonadherence and unsuppressed viral load increased through adolescence and into young adulthood.
News
Vaping-Related Pulmonary Illness May Represent New Clinical Syndrome
The recent cluster of pulmonary illnesses related to electronic cigarette use appears to represent an emerging clinical syndrome or syndromes.
New Strain of S pyogenes Causing Scarlet Fever in United Kingdom
A new strain of Streptococcus pyogenes is causing scarlet fever.
Dolutegravir and Two Tenofovir Prodrugs Noninferior to Standard HIV Regimens
Treatment with dolutegravir and either of 2 tenofovir prodrugs, tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, is noninferior to standard HIV antiretroviral regimes.
Predicting Drug-Resistant Gram-Negative Infections in Hospitalized Adults
Researchers have developed a clinical prediction tool to estimate the probabilities of third-generation cephalosporin-resistant Enterobacteriaceae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa.
Automated Assay Can Detect Hepatitis B, C Markers in Dried Blood Spots
Dried blood spot specimens could be a reliable alternative testing specimen, which may increase hepatitis B and C diagnostic opportunities for rural, remote, and hard to reach regions.
Two More Cases of EEE Virus Confirmed in Massachusetts
Two new human cases of mosquito-borne Eastern equine encephalitis were confirmed by the Massachusetts Department of Public Health.
Role of Platelets and Vascular Injury in Liver Disease Pathogenesis
In patients with chronic hepatitis C virus (HCV) with early fibrosis and cirrhosis, the decline in platelet count and growth factors (GFs) suggests that platelets are a key source of GFs and influence GF decline, according to study results published in Digestive Diseases and Sciences. The results also indicated that patients with early fibrosis had…
Model Estimates Effect of Probiotics on Costs for Flu-Like Illnesses
Probiotics could reduce the health care and economic burden of flu-like respiratory tract infections.
Novel Antifungal Gains Fast Track Designation for Seven Indications
The FDA has granted Fast Track designations to both the oral and intravenous formulations of fosmanogepix for 7 antifungal indications.
US Maternal Tdap and Influenza Immunization Rate Is Suboptimal
Maternal coverage with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) and influenza vaccinations between 2010 and 2017 remained suboptimal among large, geographically diverse cohorts in the United States. This is according to data published in the American Journal of Preventative Medicine. The data for this retrospective cohort study were extracted from the MarketScan…
Detection of Potentially Zoonotic Strongyloides Species in Canines
A form of the soil-borne Strongyloides nematode that infects humans has been identified for the first time in canine carriers in northern Australia. The findings by Flinders University environmental health researchers, along with experts in the United States, were published in PLOS Neglected Tropical Diseases. The infective larval form of the Strongyloides spp resides in…
Investigational Vaccine to Prevent RSV in Older Patients Gets Breakthrough Status
Janssen announced that the Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for their investigational prophylactic vaccine for the prevention of respiratory syncytial virus (RSV)-mediated lower respiratory tract disease in adults aged 60 years and older. RSV is a highly prevalent and contagious respiratory infection. It is the most common cause of bronchitis…
Thirty-Two Drinking Water-Related Outbreaks of Hepatitis A From 1971 to 2017
The last four reported hepatitis A outbreaks during 1995 to 2009 were due to individual water systems
ATS Guideline Outlines Lab Tests for Diagnosis of Fungal Infections
Guideline addresses lab testing for diagnosis of fungal infections in pulmonary medicine, critical care
Payment to Research Participants Can Be Coercive Without Violating Consent
Although payment for enrolling in medical research is not likely to make participation involuntary or invalid, it may create a situation that is not in the best interests of the participant.
Improving Hand Hygiene Adherence in Low-Resource Settings
Data published in JAMA Network Open suggest that the tools for the collection and rapid visualization of hand hygiene adherence data are viable in low-resource settings.
Pneumococcal Vaccination Responses Greater in Certain Patients
Serotype-specific IgG responses to the pneumococcal vaccine Pneumovax®23 were greater in patients with subnormal IgG1 than subnormal IgG3.
Considerations in Determining the Ethics of Closed Medicaid Formularies
The relatively recent submissions by state policymakers requesting to close their Medicaid formularies highlighted ethical concerns regarding access and treatment of patients who are poor or vulnerable.
Adding Video, Written Discharge Orders May Improve Recall for ED Patients
Researchers used information they gleaned from a systematic review of articles focused on discharge instructions in the ED to assess differences in comprehension or recall of verbal, verbal plus written, and verbal plus video discharge instructions.
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