Chronic Use of Immunosuppressive Drugs Does Not Worsen COVID-19 Outcomes
Study authors conducted a retrospective cohort study to assess whether chronic immunosuppression worsens outcomes for patients hospitalized with COVID-19.
News
Testing for Legionella Pneumonia in Those at Risk: Room for Improvement
Is testing for Legionella pneumophila appropriate and could it impact treatment?
Pfizer-BioNTech: COVID-19 Vaccine Trial in Pregnant Women Begins; New Storage Data Submitted to FDA
The randomized, placebo-controlled, observer-blind study is evaluating the safety, tolerability, and immunogenicity of BNT162b2 in approximately 4000 healthy pregnant women aged 18 years and older who are 24 to 34 weeks’ gestation.
Suicide Prevention in the Context of COVID-19
In an interview with Christine Moutier, MD, psychiatrist and chief medical officer of the American Foundation for Suicide Prevention, she speaks about how the current COVID-19 pandemic presents opportunities to improve suicide prevention efforts on multiple levels.
CDC Makes Masks Mandatory on Planes and Public Transportation
Face masks will be mandatory at transportation hubs and on planes and all forms of public transportation under a US Centers for Disease Control and Prevention order.
JAK-inhibitor and Type I Interferon Possible Treatments for COVID-19
Study authors conducted a systematic review and meta-analysis to assess the efficacy of Janus kinase-inhibitors and Type I interferons as potential antiviral candidates for the treatment of COVID-19.
Healthy Microbiome Is Key to Sepsis Management
The authors emphasize that sepsis treatment should be guided by the connection between the microbiota and sepsis outcomes.
Comparing Rates of STIs in Men Before and After Starting HIV PrEP
The researchers sought to determine if access to HIV PrEP was associated with preexisting trends in STIs among high-risk men who have sex with men.
FDA to Review 3-Antigen Prophylactic Hepatitis B Vaccine
The vaccine candidate consists of the S, pre-S1, and pre-S2 surface antigens of the hepatitis B virus.
Dexmedetomidine No Better Than Propofol for Adults With Sepsis
For light sedation of mechanically ventilated adults with sepsis, outcomes do not differ significantly for those receiving dexmedetomidine or propofol.
High-Titer Convalescent Plasma Therapy Within 72 Hours of COVID-19 Symptoms Reduced Risk for Severe Illness
Study authors assessed whether convalescent plasma with high SARS-CoV-2 antibody titers would prevent progression to severe disease in older patients with COVID-19 if administered within 72 hours after the onset of mild symptoms.
APPAC Trial: Uncomplicated Acute Appendicitis: Oral Antibiotics vs Intravenous Antibiotics?
Study authors compared oral moxifloxacin with combined intravenous ertapenem followed by oral levofloxacin in the managed of uncomplicated acute appendicitis.
ACIP: 2021 Child and Adolescent Immunization Schedule Updates
Fewer childhood vaccines have been administered due to a decline in outpatient pediatric visits resulting from the COVID-19 pandemic.
New Test for Diagnosis of Tuberculosis Meningitis in Patients With HIV
A new point-of-care lateral flow assay featured the same sensitivity as mycobacterial culture in detecting tuberculosis meningitis in adults with HIV.
Psychological Distress High Among Students During COVID-19
The prevalence of self-reported psychological distress among students has been relatively high during the COVID-19 pandemic.
Meta-Analysis: SARS-CoV-2 Air Contamination in Hospitals
Study authors reviewed current evidence on air contamination with SARS-CoV-2 in hospital settings, and the factors associated with contamination.
Azithromycin: Some Benefit to Pediatric Patients With HIV-Related Lung Disease
Study authors assessed whether prophylactic azithromycin can prevent worsening of lung function and reduce acute respiratory exacerbations in children with HCLD taking ART.
Risk and Severity of COVID-19 in Patients With Rheumatic Disorders Receiving DMARDs vs Methotrexate
Study authors examined the risk for admission and respiratory failure in patients with rheumatic disorders with COVID-19 receiving DMARDs or methotrexate.
Cabenuva Approved as First Long-Acting Injectable for HIV Treatment
The approval of Cabenuva was based on data from two phase 3 trials which included 1182 HIV-infected adults who were virologically suppressed (HIV-1 RNA less than 50 copies/mL) prior to initiation.
Lack of Staff, PPE Hinder Nursing Homes’ Fight Against COVID-19
Although worker turnover in the nursing home industry has always been high, the pandemic has worsened the problem.
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