| ACUTE OTITIS MEDIA TREATMENTS: NEWBORN−12 YEARS | |||||
|---|---|---|---|---|---|
| Generic | Brand | Strength | Form | Flavor | Dose |
| amoxicillin | — | 125mg/5mL, 200mg/5mL, 250mg/5mL, 400mg/5mL | susp | raspberry-strawberry | ≤3mos: Max 30mg/kg/day in 2 divided doses every 12hrs. >3mos (<40kg): 20mg/kg/day in 3 divided doses every 8hrs. Severe: 40mg/kg/day in 3 divided doses every 8hrs. ≥40kg: 250mg every 8hrs. Severe: 500mg every 8hrs Note: The AAP recommends 80–90mg/kg/day in divided doses (this is not an FDA-approved dose) |
| amoxicillin + clavulanate | — | 200mg/28.5mg, 400mg/57mg | chew tabs | cherry-banana | Base dose on amoxicillin component. <12wks: 30mg/kg/day in 2 divided doses every 12hrs (use 125mg/5mL). ≥12wks (<40kg): Twice-daily regimen: use 200mg or 400mg. Three times daily regimen: use 125mg or 250mg. 45mg/kg/day in 2 divided doses every 12hrs or 40mg/kg/day in 3 divided doses every 8hrs. ≥40kg: 500mg every 12hrs or 250mg every 8hrs |
| Augmen– tin1 |
125mg/31.25mg per 5mL | susp | banana | ||
| 250mg/62.5mg per 5mL | susp | orange | |||
| 600mg/42.9mg per 5mL | ES-600 susp | strawberry cream |
<3mos: Not recommended. ≥3mos (<40kg): 90mg/kg/day in 2 divided doses every 12hrs ≥40kg: Not recommended (use adult forms) |
||
| azithromycin | Zithromax | 100mg/5mL,
200mg/5mL |
susp | cherry-vanilla-banana |
<6mos: Not established. ≥6mos: 30mg/kg as a single dose (max 1.5g); or 10mg/kg (max 500mg) once daily for 3 days; or 10mg/kg (max 500mg) once then 5mg/kg (max 250mg) per day for 4 days. |
| cefaclor | — | 125mg/5mL, 250mg/5mL, 375mg/5mL | susp | strawberry |
<1mo: Not recommended. ≥1mo: 40mg/kg/day in 2 divided doses every 12hrs, or in 3 divided doses every 8hrs; max 1g/day |
| cefdinir | — | 125mg/5mL, 250mg/5mL | susp | strawberry | <6mos: Not recommended. >6mos: 14mg/kg every 24hrs for 10 days or 7mg/kg every 12hrs for 5−10 days; max 600mg/day |
| cefixime | Suprax | 100mg/5mL, 200mg/5mL |
susp | strawberry |
<6mos: Not established. 6mos−12yrs (<50kg): 8mg/kg once daily or 4mg/kg every 12hrs >12yrs or >50kg: 400mg once daily or 200mg every 12hrs |
| cefpodoxime | — | 50mg/5mL, 100mg/5mL | susp | lemon-creme |
<2mos: Not recommended. ≥2mos: 5mg/kg (max 200mg) every 12hrs for 5 days |
| cefprozil | — | 125mg/5mL, 250mg/5mL | susp | bubble gum |
<6mos: Not recommended. >6mos: 30mg/kg/day in 2 divided doses every 12hrs |
| ceftriaxone | — | 500mg/vial,
1g/vial |
inj | — | 50mg/kg IM once; max 1g |
| cefuroxime | — | 250mg, 500mg | tabs | — | <13yrs (able to swallow tab whole): 250mg twice daily for 10 days |
| cephalexin | Keflex | 250mg, 500mg, 750mg | caps | — | 75−100mg/kg/day in equally divided doses |
| ciprofloxacin | Otiprio2 | 6% | otic susp | — |
<6mos: Not established. >6mos: one 0.1mL (6mg) single dose into each affected ear, after effusion suctioning |
| clarithro– mycin |
— | 125mg/5mL, 250mg/5mL | susp | fruit-punch |
<6mos: Not established. >6mos: 7.5mg/kg every 12hrs for 10 days |
| sulfameth– oxazole/ trimethoprim |
— | 200mg/40mg per 5mL | susp | cherry, grape |
<2mos: Not recommended. ≥2mos: 8mg/kg of TMP (40mg/kg of SMX) per day in 2 divided doses every 12hrs for 10 days |
| NOTES | |||||
|
Key: drops = oral drops; SMX = sulfamethoxazole; susp = oral suspension (as supplied or after reconstitution); TMP = trimethoprim 1 These products should be taken with food. 2 For intratympanic administration only, in patients with effusion undergoing tympanostomy tube placement. Not an inclusive list of medications, dosing regimens, formulations, and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. Information on prophylaxis of chronic otitis media infections is not included. Under certain clinical conditions (eg, impaired renal or hepatic function), the dose may need to be adjusted. Unless stated otherwise, otitis media is generally treated for 10−14 days. Continue Reading (Rev. 5/2021) |
|||||
This article originally appeared on MPR
