The purpose of the study was to compare a composite clinical failure outcome of 60-day readmission, 60-day recurrence, and mortality in patients treated for MRSA with dual therapy vs those de-escalated to monotherapy.
A multidisciplinary panel comprising members from the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America created guidelines for health care professionals caring for patients with C difficile infection.
This is the first prospective investigation comparing the efficacy and tolerability of 2 treatments for nitroimidazole-refractory giardiasis in international travelers.
The researchers tested their hypothesis that a decrease in respiratory virus incidence would be associated with a reduction in inappropriate ambulatory antibiotic orders.
Researchers sought to determine the effect of antibiotic use on efficacy of immune checkpoint inhibitor therapy during the 12 weeks before and after initiation of therapy.
Researchers compared clinical outcomes of single vs double antipseudomonal antibiotics used to treat pulmonary exacerbations in patients with cystic fibrosis.
Investigators evaluated resistance to fluoroquinolones, nitrofurantoin, and trimethoprim-sulfamethoxazole in patients with uncomplicated urinary tract infection.
Investigators evaluated the safety and effectiveness of bezlotoxumab to prevent recurrent C difficile infection in patients having undergone solid organ or hematopoietic cell transplantation.
Investigators sought to determine the safety, tolerability, and efficacy of arterolane-piperaquine-mefloquine triple therapy vs arterolane-piperaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in children.
Investigators compared with efficacy of high-dose ceftriaxone monotherapy against that of dual therapy for Neisseria gonorrhoeae in men who have sex with men.
Investigators evaluated the impact of interventions including infectious disease consultation, addiction consultation, case management, and medications for opioid use disorder on clinical cure and retention in addiction care for individuals experiencing homelessness.
Investigators conducted a quasi-experimental, retrospective study of adult patients with COVID-19 pneumonia to evaluate antibiotic use for community-acquired bacterial pneumonia following the release of guidelines.
Researchers compared trends in antibiotic prescription rates during the period preceding the pneumococcal conjugate vaccine (PCV), as well as the early and late PCV periods, among Jewish vs Bedouin children.
