Direct-to-Consumer Sexually Transmitted Disease Testing
Despite these soaring rates, sexual behavior and STD risk are not common topics of discussion between patients and clinicians.
Diagnostics
Diagnostics
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CDC Outlines US Process of Evaluating Patients for 2019-nCoV
Recognizing individuals at risk for 2019 novel coronavirus (2019-nCoV) infection is a key part of facilitating infection control and prevention and limiting transmission.
Ebola Virus RNA May Persist in Semen, Breast Milk for Longer Than Anticipated
Data from a large sample of Ebola survivors confirmed the persistence of Ebola viral RNA in semen for up to 6 months.
CT Scan Features Described for 2019 Novel Coronavirus Infection
Key CT findings have been characterized for patients infected with the 2019 novel coronavirus.
Elderly Patients Humoral and Mucosal Immune Responses to Norovirus
Among elderly patients with norovirus infection, salivary IgA increased as early as 5 days after onset of symptoms and correlated strongly with serum IgA titers and blockade antibodies.
Effect of HCV Clearance on Cardiovascular Risks in People With HIV
In patients coinfected with HIV and HCV, eradication of HCV had no effect on markers of preclinical atherosclerosis and biomarkers of inflammation and endothelial dysfunction.
Revogene LB Assay Noninferior to GeneXpert Assay in Detecting GBS
Both the Revogene GBS LB and GeneXpert GBS LB assays perform well for the detection of Group B Streptococcal (GBS) infections in pregnant women.
Follow-Up Blood Cultures for Staphylococcus aureus Needed
Not performing follow-up blood cultures may be significantly associated with the relapse of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia.
Clinical Utility of Broad-Range Universal PCR for Pathogen Identification
Data regarding an assessment of universal broad-range PCR sequencing (uPCR) for pathogen detection published in Clinical Infectious Diseases demonstrated the utility of the technique and how to maximize its use.
PCR Demonstrates Superiority to Urine Antigen Testing for Legionellosis Diagnosis
Polymerase chain reaction testing may be superior to urinary antigen testing when diagnosing legionellosis.
Early Fungicidal Activity in CSF as Surrogate Endpoint in Cryptococcal Meningitis
Early fungicidal activity (EFA) in cerebrospinal fluid (CSF) has been associated with all-cause mortality in cryptococcal meningitis.
CDC: HIV-1/HIV-2 Differentiation Test Increasingly Used in United States
From 2010 to 2017, use of the HIV-1/HIV-2 differentiation test increased, but the number of HIV-2 diagnoses remained very low.
Disagreement on Diagnostic Use of Procalcitonin Levels
There is no consensus among the clinical practice guidelines on the use of procalcitonin for diagnosing infections.
Tuberculosis Pleural Effusion Diagnosis: Accuracy of Genotype Line Probe Assay
Despite having a good specificity for tuberculous pleural effusion diagnosis, genotype MTBDRplus line probe assay could not be included in most diagnostic algorithms as a result of its low sensitivity.
Challenges Investigating Foodborne E coli Outbreaks
A report on the largest multistate produce-linked Shiga toxin-producing Escherichia coli outbreak in the United States highlighted challenges in determining the route of contaminated lettuce and in providing rapid, actionable guidance during an outbreak.
Assessment of HAP and VAP Diagnosis, Treatment, Prevention Guidelines
Data gathered from a meta-analysis of clinical practice guidelines published in the European Journal of Clinical Microbiology and Infectious Diseases, show that well-designed randomized controlled trials are urgently needed.
Routine HPV Testing May Be Warranted for Sinonasal Cancers
Only one in four patients with sinonasal squamous cell carcinoma is tested for human papillomavirus.
The Value of Clinical and Laboratory Data for Diagnosing Drain-Associated Ventriculitis
Researchers assessed the diagnostic value of clinical factors as well as biochemical or microbiologic measures for diagnosis of drain-associated ventriculitis.
Updated Definitions for Invasive Fungal Disease
The Infectious Diseases Group of the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium (EORTC/MSGERC) have updated consensus definitions of invasive fungal diseases.
Cautions for Presumptive Diagnoses, Notably in Patients With HIV
Study authors highlighted that while diagnostic associations are helpful in suggesting diagnostic possibilities, they must be supported by clinical correlation of characteristic clinical features.
Reliance on Historic Breakpoints May Lead to False Antimicrobial Susceptibility Reports
Failure to adopt updated antimicrobial susceptibility testing breakpoints may lead to reports of false susceptibility for antimicrobials commonly used to treat Gram-negative infections and preclude recognition of CRE.
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