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Diagnostic Accuracy: A Point-of-Care Tuberculosis Test for Those With HIV

Compared with Alere Determine TB LAM Ag (AlereLAM), the only commercially available tuberculosis point-of-care test, the novel Fujifilm SILVAMP TB LAM (FujiLAM) assay offers superior diagnostic sensitivity while also maintaining specificity, according to a study published in The Lancet: Infectious Diseases. The applicability of FujiLAM in various settings requires prospective assessment, but the test could be…
Bacteria Culture

Accuracy of Rapid MALDI-TOF Bacterial Identification for Bloodstream Infections

The MALDI-TOF (Vitek MS, bioMérieux) assay demonstrated accuracy in the rapid identification of the most commonly isolated strains of Enterobacteriaceae, Staphylococcus aureus, and coagulase-negative staphylococci from colonies isolated from positive blood cultures, according to data presented at American Society of Microbiology (ASM) Microbe 2019, held June 20-24 in San Francisco, California. To test the accuracy…
cerebral spinal fluid, spin injection

CSF Parameters Not Predictive of FilmArray Meningitis/Encephalitis Panel Positivity

Cerebrospinal fluid (CSF) pleocytosis and abnormal protein and glucose levels were not predictive of a positive result on the FilmArray Meningitis/Encephalitis Panel (FA-M/E), according to research presented at American Society of Microbiology (ASM) Microbe 2019 held from June 20-24, 2019 in San Francisco, California. Researchers conducted the study to assess whether abnormal CSF parameters are…
Zika virus blood test

Suboptimal Performance of Two Commercial Zika Diagnostic Tests

The performance of 2 commercial serologic tests for diagnosing Zika virus was deemed suboptimal, according to data published in Emerging Infectious Diseases. Investigators evaluated both the Euroimmun and Dia.Pro serologic tests for detection of Zika virus immunoglobulin (Ig)M and IgG using a panel of 199 samples from a flavivirus endemic region, 90 of which were…

Type of EBV-Infected Cells Valuable in Diagnosis of Hematologic Disease

Determining the type of cell infected with Epstein-Barr virus (EBV) in peripheral blood mononuclear cells (PBMCs) proves to be a valuable tool for improving the differential diagnosis of hematologic disease with concurrent EBV infection, according to study results published in Open Forum Infectious Diseases. EBV is a herpesvirus that infects approximately 90% of the population…
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