A report on the largest multistate produce-linked Shiga toxin-producing Escherichia coli outbreak in the United States highlighted challenges in determining the route of contaminated lettuce and in providing rapid, actionable guidance during an outbreak.
Data gathered from a meta-analysis of clinical practice guidelines published in the European Journal of Clinical Microbiology and Infectious Diseases, show that well-designed randomized controlled trials are urgently needed.
The Infectious Diseases Group of the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium (EORTC/MSGERC) have updated consensus definitions of invasive fungal diseases.
Failure to adopt updated antimicrobial susceptibility testing breakpoints may lead to reports of false susceptibility for antimicrobials commonly used to treat Gram-negative infections and preclude recognition of CRE.
Toxin enzyme immunoassay more accurately identifies severe C difficile infections from strains more likely to cause recurrence, but otherwise had similar results for complications and mortality compared with the standard nucleic acid amplification test.
It appears that the common ancestor of the modern hepatitis E virus (HEV) strains emerged approximately 6800 years ago in the period following the domestication of pigs, and natural selection has played a major role in the evolution of the codon usage of HEV open reading frames (ORFs), according to study results published in BMC…
In a randomized clinical trial, the use of lithium-heparin tubes for diversion of blood prior to aspiration of culture led to a 60% decrease in blood culture contamination compared with aspiration after obtaining culture.
Diagnosing HIV using rapid screening test may not be reliable in HIV-1 controllers, a rare group of individuals living with HIV who maintain HIV viremia at extremely low or even undetectable levels in the absence of antiretroviral treatment.