Diagnostics

Latest News

Outcomes of a Multicomponent Diagnostic Strategy for Tuberculosis Infection

By

Bradley van Paridon

Researchers conducted a study that compared a multicomponent diagnostic strategy with routine care for the diagnosis and treatment of tuberculosis infection.

FDA Warns Against Using LuSys Laboratories COVID-19 Tests

By

Brian Park, PharmD

These tests have not been authorized, cleared, or approved by the FDA for distribution or use in the United States.

The Role of Lactate Dehydrogenase to Albumin Ratio in Patients With Lower Respiratory Tract Infection

By

Jessica Nye, PhD

Researchers conducted a study to determine whether the lactate dehydrogenase to albumin ratio is an independent prognostic factor predictive of in-hospital mortality in patients with lower respiratory tract infection.

Novel Outbreak Detection System That Combines Whole-Genome Sequencing, Machine Learning Shows Promise

By

Jessica Nye, PhD

Researchers sought to determine whether a novel system that combines whole-genome sequencing and machine learning is effective for detecting infectious outbreaks and identifying transmission routes of bacterial pathogens.

The Role of Fc Gamma RIIb Expression in Chronic Hepatitis B Virus Infection

By

Jessica Nye, PhD

Researchers conducted a study to determine the association between Fc gamma RIIb expression concentrations and chronic hepatitis B virus infection progression.

Assessing Acute Bacterial vs Viral Infections With C-Reactive Protein Velocity

By

Jessica Nye, PhD

Researchers conducted a study to determine whether C-reactive protein (CRP) velocity is effective for differentiating between acute viral and bacterial infections in patients with relatively decreased CRP concentrations.

Efficacy of the BBV152 Vaccine Against COVID-19 During a Delta Variant Surge

By

Jessica Nye, PhD

Researchers conducted a study to assess the effectiveness of the 2-dose BBV152 vaccine among participants with symptomatic SARS-CoV-2 infection confirmed via reverse transcription polymerase chain reaction testing.

Genetic Diagnosis of Rare Diseases Up With Genome Sequencing

Use of genomic sequencing yields an increase in genomic diagnoses across a spectrum of rare diseases.

Risk for SARS-CoV-2 Transmission From Infants vs Young Children

By

Bradley van Paridon

Researchers conducted a study that assessed SARS-CoV-2 viral loads and transmission risk among infants compared with young children.

CDC to Toughen COVID-19 Testing for International Travelers

As the world struggles with ways to stem the spread of the new omicron variant, the CDC announced that international travelers to the United States will soon have to provide a negative result from a COVID-19 test taken within 24 hours of departure.

Patient May Have Naturally Achieved a Sterilizing Cure for HIV Infection

By

Jessica Nye, PhD

Researchers evaluated the virologic and immunologic characteristics of a patient with previously confirmed HIV infection who had an undetectable HIV viral load for more than 7 years after discontinuing antiretroviral therapy.

Changes in Antimicrobial Susceptibility Patterns Vary by Type of Species and Specimen

By

Estie Mermelstein, MSN, FNP-BC

Investigators conducted a study to assess the frequency at which changes in antimicrobial susceptibility patterns occur among bacterial species isolated from the same patient.

Cerebrospinal Fluid vs Plasma HIV RNA Viral Loads in Patients With Untreated HIV Infection

By

Jessica Nye, PhD

Researchers conducted a study to determine whether patients with untreated HIV infection have consistently decreased cerebrospinal fluid HIV RNA viral loads vs plasma HIV RNA throughout various stages of the disease.

Are Nucleic Acid Amplification Tests Effective for Diagnosing Extragenital Sexually Transmitted Infections?

By

Bradley van Paridon

Researchers conducted a multicenter analysis that compared the ability of 3 nucleic acid amplification tests to detect extragenital Chlamydia trachomatis and Neisseria gonorrhoeae infections in oropharyngeal and anorectal swab specimens.

Efficacy, Safety, Tolerability of Investigational Oral COVID-19 Antiviral Candidate Paxlovid

By

Estie Mermelstein, MSN, FNP-BC

Researchers conducted a study to assess the clinical efficacy, safety, and tolerability of Paxlovid (PF-07321332/ritonavir), an oral SARS-CoV-2 Mpro inhibitor candidate for the treatment of COVID-19.

Association Between Urine Biomarkers and Acute Kidney Injury in Patients With COVID-19

By

Estie Mermelstein, MSN, FNP-BC

Researchers conducted a study to determine whether molecular biomarkers of tubular injury measured on hospital admission are a significant predictor of acute kidney injury in patients with SARS-CoV-2 infection.

Patterns, Characteristics of Children Diagnosed With Acute Flaccid Myelitis Between 2014 and 2020

By

Jessica Nye, PhD

Researchers conducted a study that compared the patterns and characteristics of acute flaccid myelitis among patients diagnosed in peak years vs those diagnosed in nonpeak years.

Racial, Ethnic Disparities in COVID-19 Testing and Outcomes

By

Estie Mermelstein, MSN, FNP-BC

Researchers conducted a study to determine the effect of patient characteristics and racial/ethnic disparities on outcomes of SARS-CoV-2 infection.

Bedside Lung Ultrasound for Diagnosing COVID-19 Pneumonia in the ED

By

Sheila Jacobs

A Danish study compared the accuracy of 3 common lung ultrasound protocols for diagnosing COVID-19 pneumonia in the emergency department.

Effectiveness of Rapid Antigen vs Reverse Transcription Polymerase Chain Reaction Tests in Ruling out SARS-CoV-2 Infection

By

Jessica Nye, PhD

Researchers conducted a study that compared the effectiveness of antigen-based rapid diagnostic testing vs reverse transcription quantitative polymerase chain reaction testing in ruling out SARS-CoV-2 infection in symptomatic patients.