MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.
A new treatment-decision score for the diagnosis of TB in children with HIV performed well, and when used in an algorithm may facilitate prompt treatment decision making for children at a high risk for mortality.
The Hologic Panther Fusion® Open Access™ system, a successfully developed and validated multiplex PCR, laboratory-developed test performed comparably to or better than a commercial reference assay.
Polymicrobial prosthetic joint infections managed with surgical debridement, antibiotics and implant retention (DAIR) had high readmission rates and deep surgical site infections.
The use of guideline recommendations from the IDSA for neuroimaging in the management of community-acquired bacterial meningitis is most likely to lead to detection of major head CT scan findings that subsequently affect clinical management.
A prevention bundle composed of 7 interventions for patients at high-risk for non-ventilator hospital-acquired pneumonia (HAP) was effective in significantly reducing HAP rates.
Polymorphisms could represent markers of immunodiscordant response in patients with HIV starting combination antiretroviral therapy with low CD4 counts.
Researchers have developed a clinical prediction tool to estimate the probabilities of third-generation cephalosporin-resistant Enterobacteriaceae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa.
The FDA has granted 510(k) clearance to binx io for a molecular point-of-care diagnostic testing platform for detecting chlamydia and gonorrhea in approximately 30 minutes.
Investigators recommend blood culture bottle system for culturing periprosthetic tissue specimens due to its ability to efficiently and rapidly detect a wider range of bacteria compared with conventional microbiology methods.
HIV testing rates are suboptimal in the United States, and there is significant regional variation in testing rates, with rural areas displaying lower rates of testing and diagnosis than urban areas.
After the first human case of leptospirosis was reported in the United States Virgin Islands following Hurricanes Irma and Maria, the US Virgin Islands arbovirus surveillance system was adapted to include leptospirosis surveillance.
