Diagnostics

Latest News

T2Candida Diagnostic Test for ICU Patients at Risk for Invasive Candidiasis

By

Infectious Disease Advisor Contributing Writer

The combination of the new test T2Candida and blood culture seemed to have the best performance in the detection of invasive candidiasis.

HPV16 Antibodies Can Develop Long Before Throat Cancer Diagnosis

Seroconversion to human papillomavirus type 16 -E6 antibody positivity can occur decades before diagnosis of oropharyngeal squamous cell carcinoma.

Fibronectin Predicts Seroclearance in Chronic Hepatitis B

By

Zahra Masoud

Fibronectin may be a potential marker for hepatitis B surface antigen seroclearance.

Gonorrhea Test ResistancePlus GC Granted Breakthrough Device Status

By

Steve Duffy

The FDA has granted Breakthrough Device designation to ResistancePlus GC,, a test that detects ciprofloxacin susceptibility.

Mouth Rinse for HPV DNA May Be Biomarker in Head, Neck Cancer

Persistent detection of tumor-type HPV DNA during treatment tied to increased risk for recurrence, death

PPD Shortage Prompts CDC to Issue New Recommendations for TB Testing

By

Diana Ernst, RPh

The CDC announced an expected 3 to 10 month shortage of Aplisol (tuberculin purified protein derivative [PPD], diluted), used as an aid in the diagnosis of tuberculosis.

T2Bacteria Panel Detects and Identifies Bloodstream Infections

By

Infectious Disease Advisor Contributing Writer

Bloodstream infections can be accurately distinguished or excluded within a 4- to 8-hour timeframe using the T2Bacteria Panel.

FDA Clears Tests for Chlamydia, Gonorrhea Using Extragenital Samples

By

Steve Duffy

The FDA has cleared the Aptima Combo 2 Assay (Hologic) and the Xpert CT/NG (Cepheid) to detect chlamydia and gonorrhea via throat and rectum samples.

Latent TB Detection: QuantiFERON-TB Gold Plus vs QuantiFERON-TB Gold In-Tube

By

Sheila Jacobs

Positive results with respect to the presence of latent tuberculosis infection in patients with renal failure were more consistent with the use of QuantiFERON-TB Gold Plus testing compared with the use of QuantiFERON-TB Gold In-Tube testing.

Four Clinical Phenotypes Identified for Sepsis

Four distinct clinical phenotypes have been identified among patients with sepsis.

Changing Characteristics of Staphylococcus aureus Bacteremia

By

Zahra Masoud

Certain Staphylococcus aureus isolates are associated with changes in clinical presentation and severity of S aureus bacteremia.

T2Bacteria Panel Accurately IDs Bloodstream Infections

The T2Bacteria Panel can rapidly and accurately diagnose bloodstream infections.

Identifying Nosocomial Influenza A: Whole-Genome vs Hemagglutinin/Neuraminidase Sequencing

By

Sweta Gupta

Whole-genome sequencing was better at identifying nosocomial influenza A outbreak clusters than hemagglutinin (HA)/neuraminidase (NA) gene sequencing.

USPSTF Urges Asymptomatic Bacteriuria Screen in Pregnancy

No evidence seen for benefits of screening nonpregnant women or men for asymptomatic bacteriuria

Skin Cultures May Aid in Prediction of Bloodstream Infection Pathogens

By

Zahra Masoud

Staphylococcus aureus and Pseudomonas aeruginosa skin cultures may help to predictthe pathogens involved in bloodstream infections.

New Scale Helps Identify More Serious Cases of Mononucleosis

Scale identifies college students at increased risk for corticosteroid Rx, chronic fatigue syndrome

HIV Transmission Rates Decreased With Prompt Diagnosis and Treatment

By

Infectious Disease Advisor Contributing Writer

Viral suppression has become increasingly prevalent in people with HIV infection in recent years, and the rates of new infections and transmissions have been decreasing.

Liver Stiffness Plus Hyaluronic Acid Measurements Improve Prognostic Ability

By

Hannah Dellabella

Investigators examined the effectiveness of combined noninvasive methods to forecast outcomes in patients with chronic liver diseases.

Optimal Limit of Detection for a Point-of-Care HCV Viremia Test

By

Virginia Schad, PharmD

Dataset of 66,640 individuals from 12 countries representative of 6 global regions confirmed that a test with a limit of detection of 1318 IU/mL would identify 97% of viremic HCV infections.

Model Can Predict Sepsis Risk for Emergency Medical Admissions

Computer-aided National Early Warning Score model model accurately predicts sepsis for emergency medical admissions.