COVID-19 Vaccine Allocation: Ethical Concerns, Practical Challenges
In the event of a likely scarcity of COVID-19 vaccines, a framework must be developed to inform who should get priority.
Emerging Diseases
Emerging Diseases
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Pre-Existing Alzheimers And Dementia Associated With Risk of Hospitalization Of COVID-19
Researchers found in an observational cohort study that pre-existing Alzheimer disease and dementia are top risk factors for severe COVID-19 based on their association with positive tests for the coronavirus in England’s hospitals in spring 2020.
Antibody Cocktail for COVID-19 Gets Emergency Use Authorization
The investigational treatment from Regeneron consists of 2 potent, virus-neutralizing antibodies.
Pfizer, BioNTech to Submit EUA Request for COVID-19 Vaccine Candidate
Pfizer and BioNTech will submit an Emergency Use Authorization (EUA) request to the FDA for their mRNA-based vaccine candidate BNT162b2 against COVID-19.
Remdesivir Superior to Placebo in Hospitalized Patients With COVID-19
Researchers assessed if use of intravenous remdesivir in hospitalized patients with coronavirus disease 2019 infection affected time to recovery and clinical status on days 15 and 29.
Social Distancing: Timing and Adherence Impact COVID-19 Cases
Researchers sought to determine the effect of social distancing measures in Dane County, Wisconsin, the Milwaukee metropolitan area, and the New York City metropolitan area.
Prepare for the End of Pandemic Telehealth Waivers
Healthcare providers should take steps now to ensure that the telehealth modalities they use are HIPAA compliant.
Ivermectin May Reduce Mortality in Hospitalized Patients With COVID-19
In hospitalized patients with coronavirus disease 2019 (COVID-19), ivermectin was associated with lower mortality compared to treatment without the antiparasitic drug.
Statin Use in Hospitalized DM Patients With COVID-19 Associated with Lower Mortality
Study authors assess the association between statin therapy and in-hospital mortality in patients with COVID-19 and concomitant diabetes mellitus.
LT-RAMP Provides Accurate and Rapid COVID-19 Detection: A Real World Study
Researchers compared a novel reverse transcription loop-mediated isothermal amplification method to the gold standard, reverse transcription polymerase chain reaction, and assessed the accuracy in detecting SARS-CoV-2.
COVID-19 Does Not Predispose Women to Early Pregnancy Loss
Investigators assessed the effect of linked HIV and SARS-CoV-2 testing on reduction in HIV incidence and indirect total health care costs.
Oral Beta-Lactams Effective Step-Down Therapy for Bacteremic UTI
Study authors compared clinical cure in patients with E coli bacteremic UTI who were stepped down to oral beta-lactams compared to oral fluoroquinolones.
Effect of PEEP in COVID-19-Related ARDS Similar to Classical ARDS
The effects of positive end expiratory pressure in COVID-19-related acute respiratory distress syndrome (ARDS) are similar to those reported in classical ARDS.
Assessing the Effect of Antimalarial Drug Shortages in Rheumatic Disease During the COVID-19 Pandemic
The COVID-19 Global Rheumatology Alliance Patient Experience Survey was used to assess the effect of antimalarial drug shortages during the COVID-19 pandemic.
CREDIBLE-CR: Cefiderocol Effective for Serious Carbapenem-Resistant Gram-Negative Infections
Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.
APEKS-NP: Cefiderocol Non-Inferior to Meropenem for Nosocomial, Gram-Negative Pneumonia
Researchers compared the efficacy and safety of cefiderocol vs high-dose, extended-infusion meropenem for adults with nosocomial pneumonia.
Final Analysis Reveals COVID-19 Vaccine Candidate BNT162b2 95% Effective
The analysis of the primary outcomes was based on 170 confirmed cases of COVID-19.
QTc Interval Prolongation After Admission for COVID-19
Prolongation of the QTc interval was found to be prevalent after 7 days of hospitalization for COVID-19.
COVID-19 Patients With Longer Hospital Stays May Have Better Psychiatric Outcomes
Researchers conducted 1-month follow-ups with patients who had either been treated at the hospital or at home for COVID-19 and found that longer hospital stays were associated with lower scores on psychopathology dimension tests.
COVID-19 With Suspected PE Shows Lung Changes Similar to Infarct, Organizing Pneumonia
Although hypercoagulability has been reported in critically ill patients with COVID-19, results from a small study revealed that these patients did not have a higher prevalence of pulmonary embolism compared to patients without COVID-19.
COVID-19 Does Not Predispose Women to Early Pregnancy Loss
Investigators assessed the relationship between infection with severe SARS-CoV-2 and spontaneous abortion.
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