COVID-19 and the Path to Endemicity
In this Q&A, Erica Johnson, MD, discussed the transition from pandemic to endemic in regard to COVID-19 infection.
Emerging Diseases
Emerging Diseases
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DDW: Antibiotics Increased Risk of Older-Onset Inflammatory Bowel Disease
Use of antibiotics, regardless of class, is associated with an increased risk of older-onset inflammatory bowel disease.
New Omicron Subvariant Rapidly Spreading in United States
Yet another subvariant of the omicron variant is spreading rapidly in the US and is likely to become the dominant strain within weeks.
Risk for Liver Injury Associated With Duration of Tigecycline Treatment
Researchers conducted a retrospective study that assessed risk factors for liver injury among hospitalized patients receiving intravenous tigecycline.
Efficacy of Standard Piperacillin Dosing in Children on Continuous Kidney Replacement Therapy
Researchers assessed the pharmacokinetics of piperacillin to determine whether standard dosing provides adequate exposure in critically ill children receiving continuous kidney replacement therapy.
Antibiotics for Less Than 24 Hours After Orthopedic Surgery Prevents Health Care-Associated Infections
Researchers assessed the effects of discontinuing antimicrobial prophylaxis within 24- vs 48-hours of clean orthopedic surgery for the prevention of health care-associated infections.
Diagnostic Stewardship Reduces Blood Cultures, Antibiotic Use in PICU
In the pediatric intensive care unit, multidisciplinary diagnostic stewardship interventions can reduce blood culture and antibiotic use.
Gram Stain-Guided Antibiotics: Effective, May Combat Spread of Multidrug-Resistant Pathogens
Researchers compared the effect of Gram stain-guided antibiotics with guideline-based antibiotics for the treatment of patients with ventilator-associated pneumonia.
Concerns Raised Over Volume of Antibiotic Prescriptions for Older Adults With COVID-19 at Outpatient Visits
Researchers assessed the rate of inappropriate antibiotic prescriptions among older adults diagnosed with COVID-19 infection at outpatient settings.
Antibiotics Within the Same Class May Not Be Ideal in Combination Therapy for Bloodstream Infections
Researchers assessed the efficacy and interaction between the 4 most common antibiotic combinations for Escherichia coli bloodstream infections.
Recurrent Diabetic Foot Infection Not Associated With Shorter Antibiotic Duration
Researchers assessed whether a shorter duration of antibiotic therapy is associated with an increased risk for recurrent diabetic foot infection.
Two New Omicron Subvariants Fueling COVID-19 Infections in New York State
Rising COVID-19 infections in New York state appear to be driven by two new versions of the omicron BA.2 variant.
Stakeholder Involvement Helps Ensure Success of Antibiotic Dispensing Interventions in Low- and Middle-Income Countries
Researchers conducted a systematic review of studies that reported on interventions to increase the rate of appropriate antibiotic dispensing in low- and middle-income countries.
Carriage of Extended-Spectrum β-lactamase-Producing Enterobacterales Associated With Number of Sexual Partners
Researchers conducted a study to determine whether the risk for extended-spectrum -lactamase-producing enterobacterales is associated with number of sexual partners and increased sexual activity.
Efficacy of Monoclonal Antibodies for COVID-19 Not Associated With Early vs Late Administration
In this retrospective cohort study, researchers assessed the rate of treatment failure among patients with COVID-19 infection who received bamlanivimab vs those who received casirivimab/imdevimab.
Neuropathic Pain: A Rare Yet Recognized Manifestation of COVID-19
This prospective case series found that some patients develop neuropathic pain.
Community-Acquired Clostridioides difficile Cases in Children on the Rise
An increase in pediatric cases of C difficile is linked to use of broad-spectrum antibiotics, recurrent infections, and a growth in highly virulent strains.
Intermediate Resistance to Penicillin, Ampicillin Common in Neisseria meningitidis Isolates
Researchers conducted an antimicrobial resistance survey that assessed Neisseria meningitidis isolates collected from patients in the United States between 2012 and 2016.
Azithromycin Therapy Does Not Reduce Recurrent Wheeze After RSV
Azithromycin therapy during acute severe respiratory syncytial virus (RSV) bronchiolitis does not reduce recurrent wheeze over two to four years.
Peripheral Neuropathy Observed in Patients With “Long COVID”
Some patients with “long COVID” have incident neuropathy, according to a study published online March 1 in Neurology: Neuroimmunology & Neuroinflammation.
Increased Virulence From COVID-19 Variants Is Similar Across Age Groups
Researchers conducted a study to determine whether increases in virulence and disease severity associated with SARS-CoV-2 variants of concern are similar across age groups.
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