A small percentage of microbiologic test results are used to direct the antibiotic stewardship processes.
Procalcitonin-guided antibiotic discontinuation was linked with greater rates of survival and reduced antibiotic utilization in critically ill individuals.
An antibacterial envelope can reduce the incidence of major cardiac implantable electronic device infections.
Consumer Reports warns of ’26-fold increase in the use of streptomycin in plant agriculture’
In patients receiving OPAT, infectious disease follow-up within 2 weeks was associated with a lower risk for all-cause 30-day hospital readmission.
More research may be needed comparing antibiotic regimens to treat Chlamydia trachomatis in men and nonpregnant women.
Impact seen in lower use of antibiotics, costs tied to health care-associated infections
The “4 Moments of Antibiotic Decision Making” provides simple, structured guidelines on antibiotic prescribing, similar to previous models pertaining to hand hygiene, central line insertion, and other practices.
Delaying or withholding antibiotics for older patients with a UTI is associated with an increase in bloodstream infection and all-cause mortality.
Continuous infusion of vancomycin, compared with intermittent infusions, was linked to earlier and improved attainment of target concentrations in infants.
New data demonstrate the potential of the Accelerate Pheno™ system to improve antimicrobial use and stewardship.
High-dose ceftriaxone, as recommended by French guidelines, was well tolerated with limited toxicity in adults with CNS infections.
A new algorithm can search administrative data for individuals with HAP and VAP, who are at significant risk for carbapenem-resistant infection.
A double-blind trial found omadacycline to be noninferior to moxifloxacin for the treatment of community-acquired bacterial pneumonia.
The use of macrolide adjunctive therapy has been shown to be safe and effective for the treatment of children with wheezing disease.
Compared with intravenous antibiotic therapy, oral therapy was noninferior when used during the first 6 weeks for complex orthopedic infections.
The risk of both Achilles tendon and bicep tendon rupture is increased with administration of fluoroquinolones.
In second study, plazomicin may be beneficial for carbapenem-resistant Enterobacteriaceae infections
Although there has been progress in the development of new antibacterial drugs, most of the recently approved agents have been modifications of existing chemical classes of antibiotics.
Early postoperative mortality may not differ between infective endocarditis caused by IDU and non- IDU causes.