Most US adults have heard of and are concerned about antibiotic resistance, but 45% report having not taken antibiotics as prescribed.
A recent study evaluated the frequency and characteristics that predicted coinfection of M genitalium and chlamydia in women.
Understanding the pneumococcal population dynamics will drive an effective next-generation vaccine design.
The combination of polymyxin B with sertraline exhibited in vitro synergistic activity against highly polymyxin-resistant Pseudomonas aeruginosa isolates from the lungs of patients with cystic fibrosis.
Compared with patients who have CSPA pneumonia, patients with CRPA pneumonia were more likely to be men and admitted from skilled nursing facilities and more often require mechanical ventilation.
A significant percentage of patients with uncomplicated urinary tract infection (UTI) are treated with an empiric antibiotic agent to which the etiologic bacteria is resistant.
Ceftobiprole was highly active against most clinical isolates of the major Gram-positive and Gram-negative skin and soft tissue infection pathogen groups.
Fosfomycin for injection may show promise and noninferiority compared with standard treatment for complicated urinary tract infections.
A new antimicrobial agent, known as ADC56, has shown efficacy and selectivity in vitro and in vivo against Gram-negative pathogens.
The sNDA is supported by data from the phase 3, double blind, DEFINE-CABP trial (N=860) which compared the safety and efficacy of Baxdela to moxifloxacin for the treatment of CABP.
Coverage with 2-dose ivermectin-based mass drug administration may have a large and sustained effect on disease prevalence.
Despite national guideline recommendations and the high prevalence of viral etiology of CAP in children, the use of antibiotics remains high.
Evidence for the treatment of MRSA pneumonia with trimethoprim-sulfamethoxazole, clindamycin, doxycycline, or minocycline was found to be based on limited data.
Less than 60% of prescriptions for the treatment of STIs in adolescents seeking care in emergency departments were filled.
New research published in Clinical Infectious Diseases describes the systematic development of 33 quality indicators for optimal outpatient parenteral antimicrobial therapy (OPAT). According to the study authors, these quality indicators are useful to assess and improve the quality of care provided by OPAT teams. Investigators used a RAND-modified Delphi procedure to develop their set of…
Treatment failure may be significantly reduced by a 3-month course of azithromycin for acute COPD exacerbations that require hospitalization.
The FDA’s Antimicrobial Drugs Advisory Committee voted in favor of pretomanid, as part of a combination regimen with bedaquiline and linezolid, for the treatment of pulmonary extensively drug resistant, treatment intolerant, or nonresponsive multidrug resistant tuberculosis.
Data on the in vitro susceptibility of urinary isolates of Escherichia coli to first- and second-line empirically prescribed oral antimicrobials were published in the International Journal of Antimicrobial Agents.
Earlier identification of single positive blood culture growing gram-positive cocci did not significantly influence vancomycin prescribing patterns.
Greater than 80% of antibiotics prescribed for infection prophylaxis prior to dental visits were found to be unnecessary.