In cases of complicated urinary tract infections (UTI) treated with multiple-dose fosfomycin, clinical resolution occurred in 2 of 3 treatment episodes.
Nasopharyngeal pneumococcal and acute otitis media isolates from children have exhibited reduced susceptibility to several antibiotic classes after the introduction of PCV-13.
Anti-methicillin-resistant Staphylococcus aureus (MRSA) therapy in addition to standard pneumonia therapy does not improve mortality.
A short, 9-month regimen of normal dose moxifloxacin maintained good effectiveness up to 24 months after therapy cessation in patients with rifampicin-resistant tuberculosis.
Veterans Affairs hospitals adopted more infection prevention practices than non-VA hospitals.
A high prevalence of antibiotic use and skin and soft tissue infections caused by community-acquired methicillin-resistant Staphylococcus aureus were identified in Indigenous Canadian communities.
Tobradex ST contains tobramycin, an antibacterial drug, and dexamethasone, a potent corticosteroid.
Pregnant women and patients with weakened immune systems (eg, HIV or AIDS) are most susceptible to severe complications from the infection.
Repeated courses of antibiotics may be associated with adverse outcomes, including admissions for infection-related complications.
In this letter to the editor, the authors raise a serious concern about the selection bias in the study by Sharara, et al with the results published in Clinical Infectious Diseases.
Exebacase is a novel, recombinantly-produced lysin (cell wall hydrolase enzyme), that targets the peptidoglycan cell wall.
The FDA has granted Orphan Drug designation to ARV-1801 (sodium fusidate; Arrevus) for the treatment of pulmonary exacerbations in patients with cystic fibrosis.
Fetroja® (cefiderocol) has been made available by Shionogi for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by the following susceptible Gram-negative microorganisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and Enterobacter cloacae complex.
For adults with exacerbation of chronic obstructive pulmonary disease, antibiotics and systemic corticosteroids are associated with less treatment failure.
Daily doses of 10 to 15 mg/kg isoniazid demonstrated similar activity against tuberculosis (TB) strains with inhA mutations as 5 mg/kg doses against drug-sensitive strains.
Dual therapy with vonoprazan and low-dose amoxicillin had similar efficacy to triple-drug treatment for the eradication of Helicobacter pylori.
Compared with patients prescribed only an antiviral, patients who are prescribed both an antiviral and antibiotic have a lower risk for 3-day respiratory hospitalization.
For patients being treated for uncomplicated acute appendicitis, quality of life (QOL) is similar at seven years after appendectomy or antibiotic therapy.
Prescribing macrolide antibiotics during the first trimester of pregnancy is associated with an increased risk for major fetal malformation.
When treating infections caused by gram-negative pan-drug-resistant bacteria, colistin and/or tigecycline-based combination empiric therapy is recommended.