Effect of Antibiotic Stewardship on Fluoroquinolone Prescribing in Hospital
Hospital-based stewardship interventions were associated with decreased fluoroquinolone prescriptions during hospitalization, but not at discharge.
Antibiotics, Antimicrobial Resistance
Antibiotics, Antimicrobial Resistance
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Microbiology Testing Has Suboptimal Effect on Antibiotic Stewardship
A small percentage of microbiologic test results are used to direct the antibiotic stewardship processes.
Procalcitonin-Guided Antibiotic Discontinuation May Increase Survival
Procalcitonin-guided antibiotic discontinuation was linked with greater rates of survival and reduced antibiotic utilization in critically ill individuals.
ACC: Antibacterial Envelope Can Reduce CIED Infections
An antibacterial envelope can reduce the incidence of major cardiac implantable electronic device infections.
EPA Proposal Will Allow Antibiotic Spraying of Citrus Crops
Consumer Reports warns of ’26-fold increase in the use of streptomycin in plant agriculture’
Early ID Follow-Up Reduces Readmission in Patients Receiving OPAT
In patients receiving OPAT, infectious disease follow-up within 2 weeks was associated with a lower risk for all-cause 30-day hospital readmission.
Inconclusive Results for Antibiotic Treament of Urogenital C trachomatis
More research may be needed comparing antibiotic regimens to treat Chlamydia trachomatis in men and nonpregnant women.
Probiotic Sanitation Cuts Antimicrobial Resistance in Hospitals
Impact seen in lower use of antibiotics, costs tied to health care-associated infections
Heeding Key “4 Moments” to Reduce Inappropriate Antibiotic Therapy
The “4 Moments of Antibiotic Decision Making” provides simple, structured guidelines on antibiotic prescribing, similar to previous models pertaining to hand hygiene, central line insertion, and other practices.
Antibiotic Delay Leads to Increased Risks in Seniors With UTI
Delaying or withholding antibiotics for older patients with a UTI is associated with an increase in bloodstream infection and all-cause mortality.
Intermittent Vancomycin Infusion Subtherapeutic Compared With Continuous Dosing
Continuous infusion of vancomycin, compared with intermittent infusions, was linked to earlier and improved attainment of target concentrations in infants.
Rapid Phenotypic Susceptibility Testing May Improve Bacteremia Management
New data demonstrate the potential of the Accelerate Pheno™ system to improve antimicrobial use and stewardship.
High-Dose Ceftriaxone Well Tolerated for Central Nervous System Infections
High-dose ceftriaxone, as recommended by French guidelines, was well tolerated with limited toxicity in adults with CNS infections.
New Algorithm Identifies Risks in Nosocomial Pneumonia
A new algorithm can search administrative data for individuals with HAP and VAP, who are at significant risk for carbapenem-resistant infection.
Omadacycline Noninferior to Moxifloxacin for Bacterial CAP
A double-blind trial found omadacycline to be noninferior to moxifloxacin for the treatment of community-acquired bacterial pneumonia.
Long-Term Effects of Macrolides in Children With Wheezing
The use of macrolide adjunctive therapy has been shown to be safe and effective for the treatment of children with wheezing disease.
Oral Antibiotics Noninferior to IV Antibiotics for Bone and Joint Infection
Compared with intravenous antibiotic therapy, oral therapy was noninferior when used during the first 6 weeks for complex orthopedic infections.
Risk of Tendon Rupture With Fluoroquinolone Use Examined
The risk of both Achilles tendon and bicep tendon rupture is increased with administration of fluoroquinolones.
Plazomicin Noninferior to Meropenem for Complicated UTI
In second study, plazomicin may be beneficial for carbapenem-resistant Enterobacteriaceae infections
Progress Made in Developing New Antibacterial Agents
Although there has been progress in the development of new antibacterial drugs, most of the recently approved agents have been modifications of existing chemical classes of antibiotics.
No Effect of IDU on Postoperative Mortality in Infective Endocarditis
Early postoperative mortality may not differ between infective endocarditis caused by IDU and non- IDU causes.
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