Metronidazole, vancomycin, fidaxomicin, meropenem, and piperacillin/tazobactam are rarely resistant to Clostridioides (Clostridium) difficile infection, while second-generation fluoroquinolones and clindamycin show highest risk.
Study authors compared clinical cure in patients with E coli bacteremic UTI who were stepped down to oral beta-lactams compared to oral fluoroquinolones.
The COVID-19 Global Rheumatology Alliance Patient Experience Survey was used to assess the effect of antimalarial drug shortages during the COVID-19 pandemic.
Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.
Investigators evaluated the relationship between delay of meropenem and vaborbactam therapy in patients with gram-negative bacterial infections and negative clinical outcomes.
Double anaerobic therapy with piperacillin/tazobactam plus metronidazole was compared to piperacillin/tazobactam alone to manage patients with intra-abdominal infections.
Investigators assessed the incidence of acute kidney injury in patients requiring vancomycin and antipseudomonal agents, particularly comparing piperacillin-tazobactam vs cefepime in combination with vancomycin.
Study authors sought to determine the effect of antibiotic use and immune checkpoint inhibitors on overall survival, profession-free survival, response rate, and progressive disease rate in cancer patients.
The incidence of acute kidney injury in patients treated with vancomycin outpatient parenteral antimicrobial therapy was assessed, and risk factors for AKI in this population were identified.
A global consensus meeting was convened to go over current evidence and knowledge gaps and propose collaborative studies on population-wide screening and eradication of Helicobacter pylori for the prevention of gastric cancer (GC).
Study authors assessed whether azithromycin in addition to a hydroxychloroquine regimen shows positive results in clinical improvement or mortality reduction in patients hospitalized with severe COVID-19.
Ertapenem and cefazolin combination therapy was studied to assess use as salvage therapy for persistent bacteremia against a MSSA blood-stream isolate.
Study authors assessed pneumococcal urinary antigen testing’s use in identifying patients for broad-spectrum antibiotic de-escalation, providing an opportunity for improved antimicrobial stewardship.
Investigators assessed the risk factors, prevalence, and epidemiology of carbapenemase-producing Enterobacteriacea in high-risk patients from ICU and HSCT wards.
Intravenous antibiotics do not achieve greater sustained eradication of Pseudomonas aeruginosa in patients with cystic fibrosis compared with oral therapy.
Researchers identified 2889 sampled antibiotic prescriptions, which translates to a national estimate of 31,548,464, to assess if prescriptions are exceeding guideline-recommended dosing for Streptococcal pharyngitis, sinusitis, AOM, CAP, SSTI, and acute cystitis.
The COVID-19 pandemic has illuminated an ongoing concern about antimicrobial resistance in dermatology and requires a recommitment from clinicians to follow guidelines that promote good stewardship.
Investigators reviewed patterns of antibiotic consumption in each of the WHO Access, Watch, and Reserve (AWaRe) categories over a span of 15 years and documented changes.
