Investigators reviewed patterns of antibiotic consumption in each of the WHO Access, Watch, and Reserve (AWaRe) categories over a span of 15 years and documented changes.
One potential driver of high antibiotic prescribing rates for acute respiratory infections is patient’s prior care experiences.
The efficacy of hormonal contraceptives may be reduced with use of antibiotics.
Antibiotic therapy was found to shorten recovery time for pediatric patients with uncomplicated appendicitis, thereby avoiding surgery.
Patients who received more than 3 types of antibiotics in the year prior to C diff onset were more likely to experience a reoccurrence of C diff infection.
Researchers investigated the relative proportions of ESBL-producing Enterobacterales vs non-ESBL-producing Enterobacterales infections in patients with ESBL-producing Enterobacterales colonization.
A team of investigators conducted a survey to update prevalence estimates of hospital antimicrobial use.
A study revealed that primary care clinicians do not closely follow clinical practice guidelines with regard to antibiotic prescribing for acute sinusitis and frequently overprescribe antibiotics.
A team of investigators conducted a systematic review and meta-analysis to assess whether a shorter-than-recommended duration of antibiotic treatment can be effective for the management of acute uncomplicated cystitis.
The CDC has reported observing a significant increase in the number of meningococcal disease cases with isolates containing a blaROB-1 β-lactamase enzyme gene, conferring resistance to penicillin antibiotics and, in some cases, ciprofloxacin as well.
Antibiotic prescription rates are high in low- and middle-income countries (LMIC), with a pooled prevalence proportion of antibiotic prescribing of 52 percent.
Researchers conducted a systematic review and meta-analysis to assess outcomes associated with ongoing antibiotic prophylaxis vs discontinuation following surgery.
An interactive, in-person barrier identification and mitigation tool can ensure safe administration of home-based outpatient parenteral antimicrobial therapy.
Fecal microbiota transplant (FMT) appears safe in decolonizing multi-drug resistant organisms (MDRO) from intestinal reservoirs in affected patients, even those who are highly immunosuppressed.
The SEPTICOLI study was conducted to determine the effect of host characteristics, bacterial virulence, and antibiotic resistance on the outcomes of patients with E coli bloodstream infections.
Patients treated with hydroxychloroquine alone or in combination with azithromycin for pneumonia associated with COVID-19 were found to be at increased risk for corrected QT interval prolongation.
The concern for development of new resistance to central lines coated with antimicrobial combinations was not validated by current clinical and experimental evidence.
Screening for extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) carriage before and personalizing prophylaxis for carriers after elective colorectal surgery reduces the risk of surgical site infections.
Linezolid use in combination therapy is effective and as safe as other firstline treatments for moderate to severe nocardiosis.
The use of acid suppressants increases the odds of multidrug-resistant microorganisms (MDROs).