Prophylactic Antibiotic Cuts Infection Risk After Operative Vaginal Birth
A single dose of a prophylactic antibiotic is beneficial after operative vaginal birth and reduces the risk for confirmed or suspected maternal infection.
Antibiotics, Antimicrobial Resistance
Antibiotics, Antimicrobial Resistance
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No Improved Outcomes With β-lactam Plus Daptomycin Therapy For S aureus
Treatment of MSSA bacteremia with a combination of β-lactam and daptomycin failed to reduce mortality compared with β-lactam monotherapy.
Macrolide Resistance Against Mycoplasma genitalium Symptomatic Male Urethritis
Mycoplasma genitalium can be the only cause of symptomatic urethritis in men who took ineffective antibiotics.
Long-Term, Prophylactic Antibiotics for UTIs Offer Little Benefit in Children
Long-term antibiotics to prevent recurrent urinary tract infections (UTIs) in children offer a modest benefit but may increase the occurrence of UTIs caused by resistant bacteria.
Procalcitonin-Guided Care as Effective as Guideline-Based Clinical Assessment in CAP
Approaches to emergency department community-acquired pneumonia care can incorporate either guideline-based serial clinical assessment or procalcitonin-driven strategies.
Similar Outcomes From Short- or Long-Course Therapy for Pseudomonal Infections
For patients with uncomplicated Pseudomonas aeruginosa bloodstream infections, the odds of recurrent infection or death within 30 days were similar for long- or short-course therapy.
Effect of Azithromycin Studied in Acute Exacerbation of COPD
Azithromycin leads to significant drops in treatment intensification and step-up in hospital care.
Association Between Antimicrobial Resistance and Climatic Factors in Europe
Climatic factors significantly contribute to the prediction of antimicrobial resistance in different healthcare systems and societies, and climate change may increase the transmission of antimicrobial resistance.
Extended Antibiotic Use Safe, Effective in Joint Infection After Total Knee Arthroplasty
In patients with a TKA periprosthetic joint infection who undergo DAIR, the addition of extended treatment with oral antibiotics appears to be safe and efficacious.
Patient Hand Contamination With Drug-Resistant Organisms Common
Link seen between patient hand contamination with resistant organisms and room surface contamination
Over-Diagnosis of UTI Syndromes in Emergency Department
Patients with suspected urinary tract infection syndromes may be unnecessarily prescribed antibiotics.
OTC Sore Throat Products May Contribute to Antibiotic Resistance
Over-the-counter throat products may be contributing to antibiotic resistance.
Delivery Mode Affects Development of Infant Gut Microbiota
Mode of delivery, independent of maternal antibiotic exposure, plays a major role in infant gut microbiota development.
Recommendations for the Evaluation, Management of Recurrent UTI in Women Released
A new clinical guideline on the diagnosis and treatment of recurrent urinary tract infections in women was released by AUA.
Ceftolozane/Tazobactam Noninferior to Meropenem for Nosocomial Pneumonia
A combination dose of ceftolozane/tazobactam is noninferior to meropenem for treating nosocomial pneumonia.
Low-Level Delamanid and Bedaquiline Resistance in Extensively Drug-Resistant TB
Researchers reported a case of drug resistance against 2 recently approved antitubercular medications: delamanid and bedaquiline.
Longer Duration of Antibiotic Use Tied to Risk for CVD in Women
For women in middle and late adulthood, longer duration of antibiotic use is associated with an increased risk for CVD events.
USPSTF Urges Asymptomatic Bacteriuria Screen in Pregnancy
No evidence seen for benefits of screening nonpregnant women or men for asymptomatic bacteriuria
Minimal Benefit of Prophylactic Antibiotics for Miscarriage Surgery
Antibiotic prophylaxis did not significantly lower the risk of pelvic infection in low- and middle-income countries when administered before miscarriage surgery.
Internet-Based Communication Training May Reduce Antibiotic Prescribing in RTIs
An internet-based training program designed to enhance communication skills in C-reactive protein point of care testing may be helpful in reducing long-term antibiotic prescribing in respiratory tract infections.
Levofloxacin Pharmacokinetics in Children With Drug-Resistant TB Exposure
The dosing recommendations regarding levofloxacin for the treatment and prevention of drug-resistant tuberculosis in children may need to be re-evaluated.
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