Compared with intravenous treatment, oral antimicrobial therapy reduced hospital stays for patients with acute pyelonephritis caused by extended-spectrum, β-lactamase-producing Enterobacteriales.
Most office-based physicians who provide STI services report not having on-site access to the recommended injectable medications for same-day treatment of gonorrhea and syphilis.
The FDA’s Antimicrobial Drugs Advisory Committee voted in favor of approval of cefiderocol for the treatment of complicated UTIs including pyelonephritis.
As a result of retrospective identification of inappropriate use of antibiotics, antimicrobial stewardship is a growing area of concern and research in medicine. This was clearly demonstrated via a plethora of poster presentations on this topic at IDWeek 2019.
A shorter course of antibiotic treatment for uncomplicated gram-negative bloodstream infections appears to be as effective as long-course antibiotic treatment.
A new scoring system for Drug Resistance in Pneumonia (DRIP) has demonstrated efficacy in improving pneumonia-related prescription trends, including a significant drop in broad-spectrum antibiotic prescriptions.
Ceftazidime-avibactam was highly active against a large collection of gram-negative bacteria isolated from patients with complicated urinary tract infections.
Researchers conducted a Phase 3 trial of patients with community acquired bacterial pneumonia and diabetes to compare delafloxacin treatment with moxiflocacin.
Researchers found data from a 10-year retrospective cohort study that showed azithromycin therapy for children with asthma was not associated with hospital readmission or length of stay.
A small but clinically significant portion of Staphylococcus aureus isolates with reduced vancomycin susceptibility also demonstrated reduced susceptibility to telavancin and daptomycin.
Healthcare professionals may inappropriately order urine cultures for patients with catheters, on the basis of subjective signs rather than evidence-based guidelines.
Researchers have developed a clinical prediction tool to estimate the probabilities of third-generation cephalosporin-resistant Enterobacteriaceae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa.
