Investigational Zika Vaccine Gets Fast Track Status
An investigational mRNA vaccine to prevent Zika virus infection has been granted Fast Track designation by the FDA.
Zika Virus
Zika Virus
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Characterization of Neurologic Manifestations in Zika Virus Infection
Neurologic manifestations associated with the Zika virus encompass a large group of clinical neurologic manifestations. Researchers found a modified Rankin scale score may help identify the risk for mechanical ventilation in certain patients with the virus.
Diagnostics in Patients At Risk for Both Dengue and Zika Infection
The CDC has summarized present and updated guidelines on dengue and Zika virus diagnostic testing in patients with a clinically compatible illness who live in or recently traveled to an endemic area.
Suboptimal Performance of Two Commercial Zika Diagnostic Tests
The performance of 2 commercial serologic tests for diagnosing Zika virus was deemed suboptimal, according to data published in Emerging Infectious Diseases. Investigators evaluated both the Euroimmun and Dia.Pro serologic tests for detection of Zika virus immunoglobulin (Ig)M and IgG using a panel of 199 samples from a flavivirus endemic region, 90 of which were…
Factors Associated With Poor Motor Function in Congenital Zika Syndrome
Factors found to affect motor function in congenital Zika syndrome were the presence of severe malformations of cortical development and small head circumference at birth.
Examining Pregnant Women’s Attitudes Toward a Zika Vaccine Trial
Pregnant women placed a high premium on clinical evidence when considering whether or not to participate in a hypothetic clinical trial of a Zika virus vaccine.
Engineered Resistance to Zika Virus in Transgenic Mosquitoes
Engineered mosquitoes may express a polycistronic cluster of synthetic RNA designed to be resistant to the Zika virus genome.
Prior Dengue Infection May Protect Against Symptomatic Zika in Children
Children with prior dengue virus infection had a decreased risk of being symptomatic when infected with Zika virus.
Neurologic and Ocular Malformations Associated With Zika Virus Infection
Researchers examined a full range of data on neurological complications in newborns and infants born to women infected with Zika virus.
Zika Vaccine Cost-Effective for Young Adults and Childbearing-Age Women
The most cost-effective means of decreasing transmission of Zika virus is administration of the vaccine to young adults and women of childbearing age.
Targeted Blood Donor Screening for Zika More Cost Effective vs Universal
Screening the donated blood supply for Zika virus is only cost-effective during the high mosquito season in Puerto Rico, but not in the United States.
Sequential Prenatal, Postnatal Neuroimaging in Zika-Exposed Infants
Sequential neuroimaging indicated that prenatal and postnatal ultrasonography may identify Zika virus-related brain injury in most patients.
Association of Hydrocephalus With Congenital Zika Syndrome
Evidence that hydrocephalus is a complication in at least a proportion of patients with congenital Zika syndrome has been published in JAMA Neurology.
Evidence of Zika Congenital Syndrome in Pre-Term Newborn
Case-study demonstrates that epithelial cells are susceptible to congenitally acquired Zika virus.
Threat of Zika Virus Still Significant in California
Since 2015, California has seen many travel-related Zika virus cases, and as the population of mosquitos that spread the virus continue to expand across the state, there is a significant risk for new Zika cases.
Sustained Follow-Up Essential for Infants of Women Exposed to Zika Virus
Approximately 14% of children who were born to mothers with confirmed or possible Zika virus infection during pregnancy were identified during infancy or early childhood as having a Zika-associated birth defect.
CDC Updates Guidance for Post-Zika Virus Exposure Counseling in Males
In an updated interim guidance, the CDC now recommends that couples wait at least 3 months before attempting to conceive after possible Zika virus exposure in the male.
Zika Virus, West Nile Virus Cases Reported in Alabama
Multiple reports of Zika virus and West Nile virus are being investigated by Alabama health officials.
Neurodevelopmental Anomalies, Birth Defects Linked to Zika ID’d
Many children of mothers with evidence of confirmed or possible Zika virus infection during pregnancy do not undergo all recommended evaluations.
Zika Virus and Dengue Fever May Be Distinguished by Select Clinical Indicators
Diagnostic indicators including conjunctivitis, platelet count, and monocyte count can be used to reliably distinguish between Zika virus and dengue fever.
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