As a ZPIV vaccine had proved to be well tolerated and immunogenic at up to 8 weeks of follow-up, investigators evaluated the safety and immunogenicity of ZPIV at up to 52 weeks of follow-up using a standard or accelerated vaccination schedules.
A high frequency of climate-change associated severe weather events have created an increased human-to-human transmission risk for novel diseases.
Infants exposed to Zika virus commonly had neuroimaging abnormalities on computed tomography and/or magnetic resonance imaging scans.
An investigational mRNA vaccine to prevent Zika virus infection has been granted Fast Track designation by the FDA.
Neurologic manifestations associated with the Zika virus encompass a large group of clinical neurologic manifestations. Researchers found a modified Rankin scale score may help identify the risk for mechanical ventilation in certain patients with the virus.
The CDC has summarized present and updated guidelines on dengue and Zika virus diagnostic testing in patients with a clinically compatible illness who live in or recently traveled to an endemic area.
The performance of 2 commercial serologic tests for diagnosing Zika virus was deemed suboptimal, according to data published in Emerging Infectious Diseases. Investigators evaluated both the Euroimmun and Dia.Pro serologic tests for detection of Zika virus immunoglobulin (Ig)M and IgG using a panel of 199 samples from a flavivirus endemic region, 90 of which were…
Factors found to affect motor function in congenital Zika syndrome were the presence of severe malformations of cortical development and small head circumference at birth.
Pregnant women placed a high premium on clinical evidence when considering whether or not to participate in a hypothetic clinical trial of a Zika virus vaccine.
Engineered mosquitoes may express a polycistronic cluster of synthetic RNA designed to be resistant to the Zika virus genome.
Children with prior dengue virus infection had a decreased risk of being symptomatic when infected with Zika virus.
Researchers examined a full range of data on neurological complications in newborns and infants born to women infected with Zika virus.
The most cost-effective means of decreasing transmission of Zika virus is administration of the vaccine to young adults and women of childbearing age.
Screening the donated blood supply for Zika virus is only cost-effective during the high mosquito season in Puerto Rico, but not in the United States.
Sequential neuroimaging indicated that prenatal and postnatal ultrasonography may identify Zika virus-related brain injury in most patients.
Evidence that hydrocephalus is a complication in at least a proportion of patients with congenital Zika syndrome has been published in JAMA Neurology.
Case-study demonstrates that epithelial cells are susceptible to congenitally acquired Zika virus.
Since 2015, California has seen many travel-related Zika virus cases, and as the population of mosquitos that spread the virus continue to expand across the state, there is a significant risk for new Zika cases.
Approximately 14% of children who were born to mothers with confirmed or possible Zika virus infection during pregnancy were identified during infancy or early childhood as having a Zika-associated birth defect.
In an updated interim guidance, the CDC now recommends that couples wait at least 3 months before attempting to conceive after possible Zika virus exposure in the male.