COVID-19: Atypical GI Presentations
There are increasing data to support that many patients with COVID-19 can develop a myriad of gastrointestinal symptoms, which include mild diarrhea, nausea, vomiting and abdominal pain.
GI Illness
GI Illness
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Gastrointestinal Infections May Be Associated With Weakened Lung Immunity
Investigators sought to better understand the immunologic mechanisms behind increased susceptibility to secondary respiratory infections.
Impact of Clostridioides difficile Infections in Hospitalized Pediatric Oncology Patients
A team of investigators sought to assess the impact of Clostridioides difficile infection on outcomes in pediatric patients with cancer.
Repeated Fecal Microbiota Transplantations in Patients With Obesity and Diabetes
Researchers studied whether combining FMT with lifestyle modifications could enhance the engraftment of favorable microbiota in patients with obesity and T2DM.
High-Dose Dual Therapy vs Bismuth Quadruple Therapy for Helicobacter pylori Eradication
Researchers compared the efficacy, adverse events, and compliance of HDDT vs BQT as first-line or rescue regimens and investigated factors contributing to H pylori eradication.
Prediction Model May Offer Better Intervention for CRE Infection After Liver Transplantation
Investigators conducted a retrospective, multinational cohort study with the intent to develop a prediction model for carbapenem-resistant Enterobacteriaceae infection after liver transplantation.
Small Intestinal Bacterial Overgrowth Linked to Poor Outcomes in Patients With Heart Failure
Investigators sought to determine the prevalence of small intestinal bacterial overgrowth and establish its prognostic value in patients with heart failure.
Leukocytosis Is Not an Independent Predictor of Clostridium Difficile
Researchers reviewed data of 16,568 consecutive patients from 4 hospitals over 4 years to determine if leukocytosis correlated with a positive C difficile NAAT results.
COVID-19 Pandemic Leads to Decrease in GI Patient Encounters and New Diagnoses of GI Cancers and Procedures
Investigators analyzed the impact of the COVID-19 pandemic on number of GI procedures performed and new cancer diagnoses.
Association Between Helicobacter pylori Infection and Chronic Kidney Disease
Investigators evaluated the relationship among Helicobacter pylori infection, atrophic gastritis, and chronic kidney disease.
Assessment of Helicobacter pylori Antibody Type on Serum Gastric Function
Researchers assessed the effects of different H pylori infections on distribution of histopathological characteristics and items of serum gastric function.
Socioeconomics, Not Pathogens, Responsible for Children’s Neurodevelopment
The investigators hypothesized that pathogens that cause diarrhea would be negatively associated with both growth and neurodevelopment.
Overcoming Current Challenges in the Development of Microbiome Drugs
To develop microbiome drugs, scientists will need to address challenges in safety, uniformity, and delivery.
High Prevalence of HCV Infection in MSM Regardless of HIV Status
The researchers’ objective was to determine the prevalence of HCV antibodies among MSM with and without HIV, as well as factors associated with HCV infection among MSM.
Extreme Gradient Boosting Shows Promise for Predicting Risk for Gastric Cancer Development After Helicobacter pylori Eradication
A team of investigators explored the ability of different machine learning models to predict the risk of gastric cancer development in patients who had undergone eradication of Helicobacter pylori infection.
Helicobacter pylori Eradication Associated With Reduced Risk of Dyslipidemia
A team of investigators conducted a large retrospective, cohort study to assess whether a longitudinal link exists between H pylori infection and the risk of developing dyslipidemia.
Hepatic Steatosis Associated With Lower Risks in Chronic Hepatitis B
This study’s goal was to study the effect of fatty liver on the incidence of cirrhosis, hepatocellular carcinoma, and HBsAg seroclearance in patients with chronic hepatitis B.
Rate of Severe GI Complications Found to Be Low in Patients Hospitalized With COVID-19
Investigators assessed the rate of severe gastrointestinal complications in patients hospitalized with COVID-19 across 36 medical centers in the United States and Canada.
Significant Decline in IBD Diagnoses and Related Procedures Seen During COVID-19 Pandemic in the Netherlands
Investigators compared the rates of inflammatory bowel disease (IBD) diagnoses made and IBD-related procedures performed during the COVID-19 pandemic with pre-pandemic rates.
Severity Score for Pediatric Shigellosis and Implications for Vaccine Trials
Study authors compared characteristics of moderate to severe diarrhea between children with culture positive Shigella and culture-negative, qPCR-attributable Shigella and derived a new clinical severity score.
No Clinical Benefit With Double Anaerobic Therapy for Intra-Abdominal Infections
Double anaerobic therapy with piperacillin/tazobactam plus metronidazole was compared to piperacillin/tazobactam alone to manage patients with intra-abdominal infections.
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