Fecal Microbiota Transplantation Superior to Fidaxomicin for Recurrent C Difficile Infection
Data from a study presents compelling evidence for the superiority of FMT in multiply recurrent CDI.
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Revised Clostridioides difficile Practice Guidelines Had Significant Effect on Treatment Decisions
Publication of the revised clinical practice guidelines for Clostridioides difficile infection was followed by significant increases in use of oral vancomycin and fidaxomicin, and a significant decrease in use of oral metronidazole.
Good Prognosis for Patients with Inflammatory Bowel Disease and COVID-19
Patients with inflammatory bowel disease (IBD) who tested positive for SARS-CoV-2 had a good overall prognosis, despite IBD maintenance treatment.
Conservative Management of Pneumonia and Upper GI Bleeding in Patients with COVID-19 Successful Without Endoscopy
Researchers showed that the management of symptoms in patients with COVID-19 pneumonia with upper GI bleeding was possible without endoscopy.
Changes to Normal Gastrointestinal Care During the COVID-19 Pandemic
The COVID-19 pandemic has caused physicians in the New York area to reevaluate how they care for patients with gastrointestinal (GI) diseases.
Microbiome-Based Therapy Looks Promising for Recurrent C Difficile Infection
“These positive preliminary findings represent a major step forward towards bringing an innovative, non-antibiotic option to patients that may help restore their gut microbiome,” said Per Falk, Ferring’s President and Chief Science Officer.
Are Patients with Inflammatory Bowel Diseases More Susceptible to COVID-19?
Inflammatory bowel diseases are known to be associated with changes in the body’s defense.
Statin Use and Acute Liver Injury Among Veterans With and Without HCV, HIV
Patients using statins had a lower risk for any acute liver injury outcome within 18 months compared with non-users, regardless of HIV and/or hepatitis C virus (HCV) status.
RHB-105 Effective for Eradication of Helicobacter pylori in Adults
A novel rifabutin-based triple therapy (RHB-105) is effective for eradication of Helicobacter pylori, with eradication rates unaffected by resistance to clarithromycin or metronidazole.
Personalized Prophylaxis for Patients With ESBL Carriage Reduces Surgical Site Infection Risk
Screening for extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) carriage before and personalizing prophylaxis for carriers after elective colorectal surgery reduces the risk of surgical site infections.
Incidence of Enteric Infections Due to Pathogens Increased or Stable
In 2019, the incidence of enteric infections caused by eight pathogens increased or remained stable.
National Burden of C difficile Infection Decreased From 2011 Through 2017
As a result of a decline in healthcare–associated infections, the estimated burden of Clostridioides difficile infection in the United States decreased by an adjusted 24% from 2011 through 2017.
MDRO Colonization Risk Increased With Gastric Acid Suppressant Use
The use of acid suppressants increases the odds of multidrug-resistant microorganisms (MDROs).
Diarrheagenic E coli Increases Risk for Reactive Arthritis and Musculoskeletal Symptoms Among Travelers
Researchers evaluated the association between diarrheagenic E coli and development of reactive arthritis and musculoskeletal symptoms among international travelers.
Pharmacokinetic Analysis of an Extended-Pulsed Fidaxomicin Regimen
Extended-pulsed fidaxomicin regimen for treatment of C difficile infection maintained fidaxomicin stool concentrations above the minimum inhibitory concentration required to inhibit the growth of 90% of organisms for 26 days.
Probiotics May Help Reduce Mild-to-Moderate Acne Symptoms
The use of probiotics as either an oral or topical treatment adjunct therapy may help in the management of acne vulgaris.
Rotavirus Vaccination Reduces Children Hospitalizations and Deaths
With increasing numbers of countries implementing the use of the rotavirus vaccine, rotavirus and acute gastroenteritis hospitalizations and mortalities continue to show a sustained reduction.
HPV Biomarkers, Survival Linked to High-Grade Esophageal Dysplasia, Adenocarcinoma
Low expression of the HPV-related marker cyclin D1 appears to be an independent prognostic marker in Barrett high-grade dysplasia and esophageal adenocarcinoma.
C difficile Risk and Antibiotic Prescription Choices
Large variations in Clostridioides difficile infection risk resulting from antibiotic courses used for the same indications were identified.
Rotavirus Vaccination Program Linked to Sustained Reduction in Healthcare Resource Utilization
A rotavirus vaccination program led to significant and sustained reductions in both hospitalizations and emergency department visits across the US.
Decreasing Prevalence of H pylori and Associated Gastric and Duodenal Ulcers
The prevalence of H pylori infection continues to fall in the general population with only 16% of all gastric and 25% of all duodenal patients with ulcer harboring H pylori.
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