E. coli

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Antibiotics, Antimicrobial Resistance

Antibiotics Within the Same Class May Not Be Ideal in Combination Therapy for Bloodstream Infections

By

Jessica Nye, PhD

Researchers assessed the efficacy and interaction between the 4 most common antibiotic combinations for Escherichia coli bloodstream infections.

Sexually Transmitted Diseases

Carriage of Extended-Spectrum β-lactamase-Producing Enterobacterales Associated With Number of Sexual Partners

By

Jessica Nye, PhD

Researchers conducted a study to determine whether the risk for extended-spectrum -lactamase-producing enterobacterales is associated with number of sexual partners and increased sexual activity.

Antibiotics, Antimicrobial Resistance

Antimicrobial Resistance, Mortality Risk Associated With Specific E coli Isolates in Patients With Bloodstream Infections

By

Shannon Storms

Researchers conducted a study that assessed antimicrobial resistance associated with specific Escherichia coli isolates in patients infected with E coli bacteremia.

General Infectious Disease

Packaged Salads Tied to E. Coli Outbreak in 6 States

More than a dozen people have been infected by a strain of Escherichia coli in 6 US states.

Pediatric Illnesses

Outcomes of Children With Acute Diarrhea Treated With Azithromycin

By

Bradley van Paridon

Researchers conducted a study to determine whether the addition of azithromycin to standard care decreases the risk of mortality among children with acute watery diarrhea.

Antibiotics, Antimicrobial Resistance

Changes in Antimicrobial Susceptibility Patterns Vary by Type of Species and Specimen

By

Estie Mermelstein, MSN, FNP-BC

Investigators conducted a study to assess the frequency at which changes in antimicrobial susceptibility patterns occur among bacterial species isolated from the same patient.

Nosocomial Infections

Risk Factors, Hospital Interventions Associated With Hospital-Acquired Bacteremia

By

Jessica Nye, PhD

Researchers conducted a study to determine the relationship between hospital interventions and the risk for hospital-acquired bacteremia.

GI Illness

Postinfectious IBS: What to Look For

By

C. Andrew Kistler, MD, PharmD

Given the overall prevalence of irritable bowel syndrome, it is important for clinicians to be able to distinguish postinfectious irritable bowel syndrome from its other subtypes.

Nosocomial Infections

Risk Factors for Surgical Site Infections Following Total Hip, Knee Replacement

By

Bradley van Paridon

Researchers conducted a study to determine the risk factors associated with postoperative surgical site infection in patients who underwent total hip or knee replacements.

Antibiotics, Antimicrobial Resistance

Insights Revealed on Antimicrobial-Resistant Bacteria Characteristics in Intensive Care Patients

By

Estie Mermelstein, MSN, FNP-BC

Investigators conducted a prospective genomic surveillance study of gut-colonizing third-generation cephalosporin-resistant Gram-negative organisms and vancomycin-resistant enterococci to improve infection prevention efforts in high-risk settings.

Genitourinary

UTI Study Maps Escherichia coli Antimicrobial Resistance Trends in the United States

By

Estie Mermelstein, MSN, FNP-BC

Investigators evaluated resistance to fluoroquinolones, nitrofurantoin, and trimethoprim-sulfamethoxazole in patients with uncomplicated urinary tract infection.

Antibiotics, Antimicrobial Resistance

Invasive E coli Infections Cause Significant Burden on US Healthcare Systems

By

Jessica Nye, PhD

Study authors conducted a retrospective, observational study to assess the prevalence and risk of recurrence of extraintestinal invasive E coli infections in the United States.

Sepsis

MERINO Trial, Post-Hoc Analysis: Relationship Between MIC and 30-Day Mortality

By

Bradley van Paridon

Study authors assessed the association of piperacillin/tazobactam MIC, meropenem MIC, and beta-lactam resistance genes with mortality in the MERINO trial.

Antibiotics, Antimicrobial Resistance

Antibiotic Resistance Not Found to Contribute to Mortality Associated With E coli Bloodstream Infection

By

Zahra Masoud

The SEPTICOLI study was conducted to determine the effect of host characteristics, bacterial virulence, and antibiotic resistance on the outcomes of patients with E coli bloodstream infections.

E. coli

Case Highlights Need for Adequate Neutrophil Count and Function in the Clearance of E coli Bacteremia

By

Sweta Gupta

Study shows ST-167, ST-940, and the isolate with an unidentifiable sequence type were cultured from blood and carried the blaNDM-5 gene, conferring phenotypic carbapenem resistance.

E. coli

Dynamics of Gut Amyloid-Producing E coli May Play a Role in T1D Onset

By

Sweta Gupta

There is a correlation between a high level of amyloid-producing Escherichia coli in the intestines, followed by their depletion due to prophage induction and the initiation of autoimmunity and type 1 diabetes (T1D) progression, according to research findings presented at the American Society for Microbiology (ASM) Microbe 2019, held June 20-24, 2019 in San Francisco,…

Antibiotics, Antimicrobial Resistance

Susceptibility of Urinary E coli Isolates to Prescribed Oral Antimicrobials

By

Bradley van Paridon

Data on the in vitro susceptibility of urinary isolates of Escherichia coli to first- and second-line empirically prescribed oral antimicrobials were published in the International Journal of Antimicrobial Agents.

GI Illness

CDC: Still No Source As E coli Outbreak Grows to 96 Cases

US health officials say an outbreak of E coli illness from an unknown source has risen to 96 cases across five Eastern states.

E. coli

Novel H pylori Eradication Therapy Effective in Phase 3 Trial

By

Steve Duffy

The ERADICATE Hp2 trial enrolled 455 dyspepsia patients at 55 sites across the US and randomized them to receive 4 capsules, 3 times daily, of either Talicia or the active comparator, for 14 days.

Antibiotics, Antimicrobial Resistance

Relationships Between Prescribing for UTI, E coli Bacteremia, Resistance

By

Bradley van Paridon

New data suggest an association between general practitioners’ prescribing habits for urinary tract infections and UTI-related E coli bacteremia incidence.