H pylori Recurrence Low One Year After Eradication

HealthDay News — The recurrence of Helicobacter pylori infection one year after eradication is low, according to a study published in the Journal of Digestive Diseases.

Li Ya Zhou, from the Peking University Third Hospital in Beijing, and colleagues assessed the recurrence rate of H pylori infection among 827 patients receiving successful H pylori eradication in a previous randomized controlled trial. A 13C-urea breath test was administered one year after eradication therapy.

The researchers found that based on an 89.8% follow-up rate (743 patients), the annual recurrence rate of H pylori infection was 1.75% (13 patients). Questionnaires completed by 692 patients (13 recurrence and 679 non-recurrence) showed that peptic ulcer disease (odds ratio [OR], 3.385), contact with other individuals with H pylori infection (OR, 4.231), and hospitalization (OR, 9.302) were independent risk factors for H pylori infection recurrence.

“The recurrence of H pylori infection one year after eradication is low in urban population of China,” the authors write.

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Zhou LY, Song ZQ, Xue Y, Li X, Li YQ, Qian JM. Recurrence of Helicobacter pylori infection and the affecting factors: a follow-up study [published online December 27, 2016]. J Dig Dis. doi: 10.1111/1751-2980.12440