Helicobacter pylori Infection Linked to Gallbladder Diseases

gallbladder lining
gallbladder lining
Study aimed to clarify the prevalence of gallbladder diseases, and factors related to gallbladder diseases, and relationships between H pylori infection, gallstones, cholecystitis, and cholecystic polypus.

HealthDay News — Gallstones are less common with Helicobacter pylori infection among a Chinese population, according to a study published in the Journal of Gastroenterology & Hepatology.

Mei-Yan Xu, from the Aerospace Center Hospital in Beijing, and colleagues assessed the relationship between H pylori infection and gallbladder diseases among 17,971 healthy participants.

The researchers found that 43.4% of participants had H pylori infection, 5.5% had gallstones, 1.2% had cholecystitis, and 5.6% had cholecystic polyps.

Among participants ≤45 years in the H pylori-positive group, the prevalence of gallstones was lower than in the H pylori-negative group (odds ratio, 0.653).

In the H pylori-positive group, the prevalence of cholecystic polyps was significantly higher than that seen in the H pylori-negative group (odds ratio, 1.160).

H pylori infection is found to be related to cholecystic polyps and gallstones,” the authors write.

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Xu MY, Ma JH, Yuan BS, et al. Association between helicobacter pylori infection and gallbladder diseases: a retrospective study [published online November 27, 2017]. J Gastroenterol Hepatol. doi: 10.1111/jgh.14054.