Noninvasive Biomarker of Variceal Bleeding in HCV Cirrhosis
Although hepatic vein pressure gradient measurement is an accurate method for evaluation of portal HTN, this technique is invasive and not widely available.
Hepatitis
Hepatitis
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Treatment Regimens and Recommendations for HIV/HCV Coinfection
Experts discuss the management of drug-drug interactions in patients receiving treatment for HIV and HCV coinfection. -
The Changing Face of HCV: Role of the Opioid Epidemic
The opioid epidemic has fueled the transmission of HCV, particularly among younger persons, who are often unaware of their risks and prevented from receiving timely treatment due to a variety of care barriers, even in settings ideally suited to identifying and treating HCV. -
Racial Disparities in HCV Incidence and Treatment Outcomes
Racial disparities in HCV treatment outcomes can be partially explained by the differences in underlying immune/genetic characteristics of patients. -
Short-Duration Treatment Regimens for Chronic HCV: Latest Insights
The high cost of DAA-based regimens remains an ethical issue and an obstacle to treatment accessibility. Shorter treatment regimens may offer substantial cost savings, improved treatment adherence, and a reduced rate of side effects.
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Specific Biomarkers of Liver Fibrosis Suboptimal in HIV/HCV Coinfection
APRI and FIB-4 biomarkers may be unsatisfactory for the detection of significant fibrosis and cirrhosis in people with HIV and HCV.
Universal Prenatal Hepatitis C Virus Screening Improves Health Outcomes
Universal prenatal HCV screening was found to be cost-effective and improved health outcomes in women diagnosed with HCV infection and identification of HCV exposure in neonates.
HBV, HCV, and HIV Screening Results of Deceased Solid Organ Donors
Increased risk donors may be significantly more likely to be HCV- and HBV-positive compared with standard risk donors.
Clinical Features and Determinants of Chronic Hepatitis E Infection
The Journal of Viral Hepatitis has published a review of the clinical manifestations of chronic hepatitis E virus.
Many Patients Are Unwilling to Accept Transplantation of an HCV-Positive Organ
The availability of organs that are positive for HCV can potentially decrease the length of time on organ transplantation waitlists.
Sofosbuvir-Velpatasvir Safe and Effective for Some Patients With Chronic HCV
Sofosbuvir-velpatasvir administered for 12 weeks is efficacious and safe for Asian patients with chronic HCV.
Alkaline Phosphatase Threshold Marks Significant Fibrosis in Hepatitis B
Levels of serum alkaline phosphatase above 69.5 IU/L can distinguish significant fibrosis in individuals with chronic HBV who are e-antigen-negative.
Hepatitis A Vaccine Safe in Childhood-Onset SLE
Inactivated hepatitis A vaccine may be safe and well tolerated in childhood-onset systemic lupus erythematosus.
High Hepatitis C Prevalence in Western and Appalachian US States
In the US, the prevalence of HCV is comparatively higher in the western and Appalachian states.
CDC: Proportion of Increased-Risk Deceased Organ Donors on Rise
Increased-risk donors significantly more likely to have positive HBV, HCV screening results.
Hepatitis D Is More Prevalent in US Than Previously Thought
Researchers found that the US population has a higher prevalence of hepatitis D virus, which could be lowered with vaccinations.
Many New Cancer Patients Unaware of Their Hepatitis Status
Large proportion of participants with newly diagnosed cancer learned of infection through study.
Ledipasvir-Sofosbuvir Treatment for Chronic Hepatitis C Virus Infection
Ledipasvir-sofosbuvir treatment for chronic HCV infection may be efficacious, safe, and tolerable for HCV genotype 1 and 4.
Supply Updates Announced for Recombivax HBV Vaccines
The information, posted to the Food and Drug Administration (FDA) website, states that both the Recombivax HB adult (10mcg/mL) and dialysis (40mcg/mL) formulations are not expected to be available in 2019.
Glecaprevir/Pibrentasvir Effective, Well-Tolerated in Older HCV Patients
Due to the limited amount of published literature analyzing treatment options for older chronic HCV infection patients, the study authors aimed to determine the efficacy and tolerability of glecaprevir/pibrentasvir in this population.
FDA: Chocolates, Candies May Be Contaminated With Hepatitis A
Worker at Bauer’s Candies facility in Kentucky tested positive for hepatitis A.
USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit
The USPSTF recommends hepatitis B virus (HBV) infection screening in pregnant women at their first prenatal visit.
Population Based Screening Crucial for Early Diagnosis/Treatment of STIs
Adopting suitable protocols for the early diagnosis of STIs is necessary to allow implementation of prevention measures that will safeguard public health.
Temporary Decline in CD4 T-Cell Count After Hepatitis C Infection in PLWHIV
When hepatitis C is acquired in patients with HIV infection, CD4 T-cell counts temporarily decline after HCV seroconversion.
Tenofovir Disoproxil Fumarate Approved for Use in Younger Patients With HBV
The Indication section has been revised to state that Viread is intended for use in the treatment of chronic hepatitis B in adults and pediatric patients 2 years of age and older weighing at least 10kg.
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