Merck has provided several updates regarding supply issues surrounding its hepatitis B vaccine, Recombivax HB (hepatitis B surface antigen vaccine [recombinant]; Merck).

The information, posted to the Food and Drug Administration (FDA) website, states that both the Recombivax HB adult (10mcg/mL) and dialysis (40mcg/mL) formulations are not expected to be available in 2019. Recombivax HB is a vaccine indicated for prevention of infection caused by all known subtypes of hepatitis B virus. It is approved for use in individuals of all ages. Recombivax HB Dialysis Formulation is approved for use in predialysis and dialysis patients 18 years of age and older.

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As for the pediatric/adolescent formulation (5mcg/0.5mL), the Company states that the vaccine will not be distributed through the second quarter of 2019. To address the gap in pediatric hepatitis B vaccine supply, GlaxoSmithKline will increase production of both single-component vaccine (Engerix-B) and combination vaccine (Pediarix). Guidance for completing the hepatitis B series during the Recombivax HB shortage can be found here.

For more information visit FDA.gov.

This article originally appeared on MPR