Rates of HIV-associated dementia have decreased from approximately 50% in the pre-cART era to 2% currently. However, roughly 50% of patients treated with cART have the milder forms of HIV-associated neurocognitive disorder (HAND).
This article describes the populations at high risk for HIV infection and reports the results of a collaborative, multifaceted educational intervention designed to reduce the documented disparities related to HIV care and prevention.
HIV-positive patients in the United States face significant challenges associated with poor adherence to antiretroviral therapy (ART) and HIV-1 drug resistance, according to a study published in AIDS and Behavior.
Initiation of dolutegravir-based antiretroviral therapy in the third trimester of pregnancy was associated with a greater number of women having a viral load <50 copies/mL at the time of delivery as compared with efavirenz-based therapy.
Patients who are HIV-positive with a probable or proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may not be at a greater risk for severe disease or death compared with patients who are HIV-negative,
In terms of screening for obstructive sleep apnea in people living with HIV, the STOP-BANG questionnaire had good sensitivity, whereas the Berlin questionnaire and the Epworth Sleepiness Scale demonstrated good specificity.
In people with HIV and plasma HIV RNA below the limit-of-quantification, discordant shedding of HIV RNA and DNA sequences from the genital tract was inferred to be from the proliferation of infected cells with virion production.
Although tenofovir alafenamide coformulated with emtricitabine has a marginally more benign side effect profile compared with tenofovir disoproxil fumarate coformulated with emtricitabine the additional cost of the newer HIV PrEP is not justifiable.