Rates of HIV-associated dementia have decreased from approximately 50% in the pre-cART era to 2% currently. However, roughly 50% of patients treated with cART have the milder forms of HIV-associated neurocognitive disorder (HAND).
A scientific statement from the American Heart Association was published in Circulation, with the purpose of providing a thorough review of available evidence on HIV-associated cardiovascular disease.
This article describes the populations at high risk for HIV infection and reports the results of a collaborative, multifaceted educational intervention designed to reduce the documented disparities related to HIV care and prevention.
Researchers assessed the characteristics of children who tested positive for HIV diagnosed with HIV infection at the primary healthcare level, across all provinces of South Africa, their attendance at study-specific exit interviews, and their reported uptake of HIV-related care.
Investigators compared a dolutegravir-based regimen with an EFV400-based reference regimen in adults in Cameroon infected with HIV-1, considering viral suppression at week 48, in particular.
The FDA has approved Descovy for HIV-1 PrEP in at-risk adults and adolescents (≥35kg) to reduce the risk of sexually acquired HIV-1 infection, excluding individuals at-risk from receptive vaginal sex.
A new treatment-decision score for the diagnosis of TB in children with HIV performed well, and when used in an algorithm may facilitate prompt treatment decision making for children at a high risk for mortality.
HIV treatment and virologic failure, and sustained viral response at week 12 or 24 were not different among patients who did or did not undergo a switch in their antiretroviral therapy regimen prior to DAA treatment.
Approximately 1 in 5 people with HIV also has prevalent DM, and control of hemoglobin A1c levels in these patients may have a beneficial effect on CD4 counts.
Switching antiretroviral therapy in virologically suppressed patients provides a robust option for preserving bone health while continuing suppressive HIV treatment.
Patients infected with HIV and taking tenofovir disoproxil fumarate as antiretroviral therapy have a greater risk for estimated glomerular filtration rate reduction if they have a lower body weight.
HIV testing in South African emergency departments shows a high prevalence and incidence of HIV, as well as significant attrition along the HIV care cascade for HIV-positive individuals.
Polymorphisms could represent markers of immunodiscordant response in patients with HIV starting combination antiretroviral therapy with low CD4 counts.
Results from an umbrella review of observational studies showed highly suggestive or suggestive evidence for HIV and the presence of several physical health outcomes.
