Neurocognitive Conditions Among People Living With HIV
Neurologic conditions associated with HIV remain major contributors to morbidity and mortality, and are increasingly recognized in the aging population of individuals living with HIV.
HIV/AIDS
HIV/AIDS
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An Overview of HIV-Associated Neurocognitive Disorder
Rates of HIV-associated dementia have decreased from approximately 50% in the pre-cART era to 2% currently. However, roughly 50% of patients treated with cART have the milder forms of HIV-associated neurocognitive disorder (HAND). -
AHA Guidelines for Prevention and Management of Cardiovascular Disease in HIV
A scientific statement from the American Heart Association was published in Circulation, with the purpose of providing a thorough review of available evidence on HIV-associated cardiovascular disease. -
Improving HIV Prevention for Underserved, At-Risk Populations
This article describes the populations at high risk for HIV infection and reports the results of a collaborative, multifaceted educational intervention designed to reduce the documented disparities related to HIV care and prevention. -
HIV Control Criteria: Overview & Expert Roundtable
Although the overall number of new HIV infections has declined worldwide, it is estimated that 5000 new infections occur each day.
Latest News
Variation in Assays that Identify Early HIV Antibody Seroconversion
A study evaluated 5 commercially available assays that are approved for HIV seropositivity confirmation and could be readily performed in clinical laboratories.
CDC: HIV Testing Occurs at <1% of Physician Visits
HIV testing occurs at less than 1 percent of physician office and emergency department visits and at less than 3 percent of community health center (CHC) visits.
Factors Contributing to Poor ART Adherence, HIV-1 Drug Resistance Explored
HIV-positive patients in the United States face significant challenges associated with poor adherence to antiretroviral therapy (ART) and HIV-1 drug resistance, according to a study published in AIDS and Behavior.
Similar Risk for COVID-19 in HIV-Infected Individuals, General Population
Investigators conducted a study at a Spanish hospital to identify characteristics of COVID-12 infection in individuals with HIV.
Prevalence of Hepatic Steatosis in HIV-infected Individuals
A team of investigators from Denmark sought to determine the prevalence of hepatic steatosis in people with HIV vs those without the infection.
Efficacy of Dolutegravir vs Efavirenz ART in Late Pregnancy
Initiation of dolutegravir-based antiretroviral therapy in the third trimester of pregnancy was associated with a greater number of women having a viral load <50 copies/mL at the time of delivery as compared with efavirenz-based therapy.
PrEP Awareness and Engagement Lowest in Adolescents With Greatest Risk for HIV
The uptake rate of pre-exposure prophylaxis (PrEP) for HIV prevention has remained low, especially among at-risk adolescents.
Latent Tuberculosis Associated With Higher Alcohol Use in Adults With HIV
Very high alcohol use is associated with latent tuberculosis infection (LTBI) among adults living with HIV in Uganda.
HIV Not Linked to Increased Risk for Severe COVID-19
Patients who are HIV-positive with a probable or proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may not be at a greater risk for severe disease or death compared with patients who are HIV-negative,
Specificities and Sensitivities of OSA Screening Tools for People With HIV
In terms of screening for obstructive sleep apnea in people living with HIV, the STOP-BANG questionnaire had good sensitivity, whereas the Berlin questionnaire and the Epworth Sleepiness Scale demonstrated good specificity.
Pediatric HIV Exposure or Infection Linked to S pneumoniae and P jirovecii Carriage Prevalence, Density
Pediatric HIV infection and HIV exposure without infection both had an association with carriage prevalence and densities for Streptococcus pneumoniae and Pneumocystis jirovecii.
Genital Shedding of HIV When Plasma RNA Is Undetectable
In people with HIV and plasma HIV RNA below the limit-of-quantification, discordant shedding of HIV RNA and DNA sequences from the genital tract was inferred to be from the proliferation of infected cells with virion production.
Men With HIV Are Not Receiving STD Testing, Prevention Services
Many sexually active men who have sex with men (MSM) do not receive recommended prevention services and sexually transmitted disease (STD) testing when receiving care for HIV infection.
Statin Use and Acute Liver Injury Among Veterans With and Without HCV, HIV
Patients using statins had a lower risk for any acute liver injury outcome within 18 months compared with non-users, regardless of HIV and/or hepatitis C virus (HCV) status.
HIV-1 Salvage Therapy Can Omit NRTIs and Remain Efficacious and Safe
People with HIV-1 infection who have virologic failure can safely omit nucleoside reverse transcriptase inhibitors (NRTIs) in new regimens that include > 2 active drugs.
Children With HIV Receiving ART May Have Deficits in Bone Architecture and Strength
Children living with HIV demonstrate deficits in bone architecture and reductions in bone strength, compared with children without HIV.
Health Benefit of Newer HIV PrEP Do Not Outweigh Cost Effectiveness of Older Formulation
Although tenofovir alafenamide coformulated with emtricitabine has a marginally more benign side effect profile compared with tenofovir disoproxil fumarate coformulated with emtricitabine the additional cost of the newer HIV PrEP is not justifiable.
Darunavir/Ritonavir With Rifampicin May Be Hepatotoxic
Darunavir/ritonavir administered with rifampicin causes hepatotoxicities in people living with HIV.
Higher Rate of Dyslipidemia Among Women Living With HIV
Despite relatively young ages, a significantly greater percentage of women living with HIV had dyslipidemia than did controls.
Expansion of PrEP Coverage Decreases HIV Diagnosis Rates
Expanding daily oral antiretroviral pre-exposure prophylaxis to persons at high risk for HIV may accelerate the reductions in new HIV diagnoses in the United States.
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