Rates of HIV-associated dementia have decreased from approximately 50% in the pre-cART era to 2% currently. However, roughly 50% of patients treated with cART have the milder forms of HIV-associated neurocognitive disorder (HAND).
A scientific statement from the American Heart Association was published in Circulation, with the purpose of providing a thorough review of available evidence on HIV-associated cardiovascular disease.
This article describes the populations at high risk for HIV infection and reports the results of a collaborative, multifaceted educational intervention designed to reduce the documented disparities related to HIV care and prevention.
Treatment with cotrimoxazole in infants exposed to HIV but uninfected (HEU) increases resistance gene prevalence and α-diversity and decreases microbial taxonomic, functional pathway, and resistance gene β-diversity.
The prevalence of neural tube defects is 7.0 per 10,000 live births in HIV-exposed pregnancies, which is similar to the prevalence in the general population.
Data published in JAMA Network Open suggest that prescribing practices of antiretroviral therapy (ART) in pregnant women living with HIV in the United States do not align optimally with national guidelines. In this prospective cohort study including data from 1867 pregnancies in 1582 women living with HIV, 49.5% were associated with prescribed ART designated as…
Starting antiretroviral therapy (ART) for HIV-infected infants within hours of birth does not seem to result in a higher proportion of infants who attain and sustain viral suppression on ART.
The researchers suggest including information about bone-healthy lifestyle in the management of PLWHIV, as well as earlier initiation of osteoporosis prophylaxis and treatment.
An evaluation of the FDA program to review antiretroviral drugs for use in low-resource settings, conducted by the PEPFAR, showed that the FDA’s efforts have made many HIV drugs available for use globally.
The implications of expanding HIV pre-exposure prophylaxis coverage in men who have sex with men on sexually transmitted infection epidemics vary depending on the benefit to the individual or the population.
Study authors highlighted that while diagnostic associations are helpful in suggesting diagnostic possibilities, they must be supported by clinical correlation of characteristic clinical features.
Diastolic dysfunction was associated with multiple alterations in cardiac structure and function in a contemporary HIV-positive population receiving antiretroviral therapy.
Compared with injectable contraceptive norethisterone enanthate and combined oral contraceptive pills, contraceptive vaginal ring lowered cervical frequencies of Th17 cells, which may affect HIV risk stratification.
The gold salt auranofin may be a promising addition to antiretroviral therapy (ART) to target individuals categorized as latent viral reservoirs of HIV-1.
Although the prevalence of distal sensory peripheral neuropathy decreased following initiation of cART in people living with in resource-limiting settings, better strategies are needed.
