Researchers compared the efficacy and safety of cefiderocol vs high-dose, extended-infusion meropenem for adults with nosocomial pneumonia.
Investigators assessed the risk factors, prevalence, and epidemiology of carbapenemase-producing Enterobacteriacea in high-risk patients from ICU and HSCT wards.
The efficacy, immunogenicity, and safety of a Clostridioides difficile toxoid vaccine candidate was assessed.
Findings from a study published in JAMA Network Open suggest that rigorous infection control measures may be associated with minimized risk and provide reassurance to patients concerned about contracting COVID-19 in hospitals.
There is a low incidence of second PJI in patients with bacteremia or hematogenous periprosthetic joint infection with concomitant prosthetic implants.
The use of prophylactic oral antibiotic in the day prior to elective colon surgery is associated with a reduced incidence of surgical-site infections.
Investigators assessed patients who hospitalized with microbial S aureus bacteremia to determine the most meaningful cutoff point to define S aureus persistent bacteremia.
Investigators analyzed a potential link between community-acquired Staphylococcus aureus bloodstream infection and increased short-term risk for myocardial infarction, which is associated with subsequent mortality.
Patients who received more than 3 types of antibiotics in the year prior to C diff onset were more likely to experience a reoccurrence of C diff infection.
Genomically-confirmed assessments of the risk for CDI found that asymptomatic carriers serve as viral reservoirs in clinical settings.
Research results underscore the importance of understanding the characteristics of Legionnaires’ disease and the need for early diagnosis.
Children with GII.4 type norovirus had more severe symptoms and required more medical care.
Four medical societies have come together to publish an updated consensus guideline on dosing and monitoring vancomycin for the treatment of serious MRSA infections.
In immunocompromised adults, community-acquired pneumonia should be treated by a multidisciplinary team of physicians.
Treatment with daptomycin for bacteremia caused by methicillin-resistant Staphylococcus aureus complicated by septic pulmonary emboli was found to have a success rate comparable to daptomycin-ceftaroline fosamil.
According to Mylan, the administration of the recalled product may lead to “serious adverse events including, but not limited to, local irritation, vasculitis/phlebitis, antigenic or allergic reactions, and microvascular obstruction, including pulmonary embolism.”
Upon starting methotrexate treatment, LDH and albumin levels may be signals for AKIs in patients with hematologic malignancies.
A retrospective study of CMV-seropositive adults receiving allogeneic HCT and CMV-seronegative HLA-matched sibling donors found that vancomycin exposure before HCT increased the risk for CMV reactivation.
A post hoc analysis was conducted to assess the efficacy of bezlotoxumab in a subgroup of participants from the MODIFY I and II trials.
An interactive, in-person barrier identification and mitigation tool can ensure safe administration of home-based outpatient parenteral antimicrobial therapy.