With increasing numbers of countries implementing the use of the rotavirus vaccine, rotavirus and acute gastroenteritis hospitalizations and mortalities continue to show a sustained reduction.
Baloxavir inhibits the endonuclease activity of the polymerase acidic protein resulting in inhibition of influenza virus replication.
The incidence of developing tuberculosis is high among exposed infants and young children.
Research results revealed increased risks for cardiovascular disease and insulin resistance among young individuals with HIV.
Dolutegravir (DTG)-based regimen may lead to significant improvement in blood lipid concentration, and no interference on glucose metabolism, but a relevant increase in trunk fat without alterations of body mass index (BMI) and body fat percent among youth with HIV. The results of this research were presented at the virtual Conference on Retroviruses and Opportunistic…
Nasopharyngeal pneumococcal and acute otitis media isolates from children have exhibited reduced susceptibility to several antibiotic classes after the introduction of PCV-13.
A protein epitope targeted by the antibody response in children with Kawasaki disease has been identified.
A rotavirus vaccination program led to significant and sustained reductions in both hospitalizations and emergency department visits across the US.
Implementation of an influenza immunization program increased vaccinations rates from 44% to 57% the following year.
Symtuza is a 4-drug combination of darunavir, an HIV-1 protease inhibitor; cobicistat, a CYP3A inhibitor; and emtricitabine and tenofovir alafenamide.
Less than one-quarter of infants exposed to hepatitis C virus (HCV) receive testing.
The risk of acquiring a sexually transmitted infection (STI) is not higher among adolescents using long-acting reversible contraceptives.
Study shows ST-167, ST-940, and the isolate with an unidentifiable sequence type were cultured from blood and carried the blaNDM-5 gene, conferring phenotypic carbapenem resistance.
Communication between pediatricians and adolescent boys who engage in same-sex sexual intercourse may be a potential avenue to increase HIV testing.
Youth newly diagnosed with HIV are linked to care at similar rates as adults but achieve disproportionately lower rates of viral suppression.
D46/NS2/N/ΔM2-2-HindIII vaccine candidate had excellent infectivity and immunogenicity, and is primed for anamnestic responses.
Prescribing macrolide antibiotics during the first trimester of pregnancy is associated with an increased risk for major fetal malformation.
The CDC continues to recommend influenza vaccination as the best method of protection while the viruses are circulating in the community.
For many PICO questions, the literature review failed to identify sufficient data to develop strong recommendations for children with septic shock or other sepsis-associated organ dysfunction.
One in three children are prescribed antibiotics at children’s hospitals, and 25.9% prescribed antibiotics for infectious use are receiving at least one suboptimal antibiotic