Prescribing macrolide antibiotics during the first trimester of pregnancy is associated with an increased risk for major fetal malformation.
The CDC continues to recommend influenza vaccination as the best method of protection while the viruses are circulating in the community.
For many PICO questions, the literature review failed to identify sufficient data to develop strong recommendations for children with septic shock or other sepsis-associated organ dysfunction.
One in three children are prescribed antibiotics at children’s hospitals, and 25.9% prescribed antibiotics for infectious use are receiving at least one suboptimal antibiotic
In pediatric patients, the duration of antibiotic treatment for uncomplicated UTI was not significantly associated with UTI recurrence.
4CMedB, a new multi-antigen vaccine designed to control group B meningococcal disease, had no effect on carriage of disease-causing meningococci in adolescents.
Antibiotics do not appear to be associated with childhood obesity.
Early initiation of antiretroviral therapy (ART) prevents disease progression and shortens time to viral suppression in infants with HIV.
During the period from 2010 to 2016, parents of children from low-income households were more likely to report recent childhood GI and respiratory illnesses than parents with a higher income.
The DTaP-IPV-Hib-HepB vaccine has safety profile consistent with licensed comparator vaccines and has been included in the federal Vaccines for Children program.
Updated recommendations for the use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine have been developed by the Advisory Committee on Immunization Practices (ACIP).
Nebulized normal saline, which is often used as a placebo in clinical trials evaluating therapies for acute viral bronchiolitis, may be an active treatment for this condition.
There are no major differences in pregnancy outcomes for women with HIV related to receipt of protease inhibitors, non-nucleoside reverse transcriptase inhibitors, or integrase strand transfer inhibitors.
The ACIP has released an updated version of the child and adolescent immunization schedule for ages 18 years and younger in the United States.
The prevalence of neural tube defects (NTDs) in births to mothers with HIV from 2013 to 2017 was estimated to be 7.0 per 10,000 live births.
Both the Revogene GBS LB and GeneXpert GBS LB assays perform well for the detection of Group B Streptococcal (GBS) infections in pregnant women.
The FDA has approved fidaxomicin for the treatment of Clostridioides difficile-associated diarrhea in adult and pediatric patients aged 6 months and older.
The outpatient antibiotic prescribing rate for children was 1,165 per 1,000 in Tennessee in 2016.
Over a 2-year period, roughly half of positive cases of rotavirus in infants were the result of vaccine-related viral shedding.
In an observational cohort study, details are presented for an outbreak of enterovirus A71 (EV-A71) neurological disease in children who presented to a Colorado hospital for treatment.