Countries’ Mitigation Measures Crucial for Containing Spread of COVID-19
The effect of COVID-19 response in China shows that quarantine, social distancing, and isolation of infected persons can contain the epidemic in other countries.
Prevention
Prevention
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20-Valent Pneumococcal Conjugate Vaccine Safe, Immunogenic in Phase 3 Trial
Pfizer announced topline data from one of its phase 3 studies for 20vPnC for the prevention of invasive disease and pneumonia.
Medications for OUD Reduces Rates of Overdose and Endocarditis
Patients with opioid use disorder (OUD) who receive medications for OUD following endocarditis may experience improved health-related outcomes.
Antimalarials May Cut Risk for Type 2 Diabetes in Lupus Patients
Adherence to antimalarials may offer a protective effect against type 2 diabetes mellitus among patients with systemic lupus erythematosus.
Infection Prevention Is Widely Practiced Across Veterans Affairs Hospitals
Veterans Affairs hospitals adopted more infection prevention practices than non-VA hospitals.
Hand-Hygiene Adherence Varies at Critical Points of Care
Healthcare workers were more likely to partake in hand-hygiene protocols after contaminating tasks vs critical tasks and before such tasks.
CMV Exposure at Transplantation Is an Independent Predictor of Thrombotic Events
Donor cytomegalovirus seropositivity at transplantation was associated with an increased risk for thrombotic events post-transplantation.
CMV Vaccine May Prevent Viremia in Hematopoietic Stem Cell Transplant Recipients
Triplex, a modified recombinant attenuated poxvirus vaccine engineered to induce a virus-specific T-cell response to control CMV in recipients of allogeneic hematopoietic stem cell transplant was safe and well tolerated.
Harnessing Key Elements of the Ebola Virus in Animal Models of Glioblastoma
A glycoprotein in Ebola called the mucin-like domain may be of interest in the development of an oncolytic for brain cancer.
Vaccine to Prevent Ricin Intoxication Gets Fast Track Status
The FDA has granted Fast Track designation to RiVax® for the prevention of ricin intoxication.
Coagulation Disorders and Bleeding Risks With Cefoperazone-Sulbactam
Of patients who received cefoperazone-sulbactam, 9.2% reported a coagulation disorder and 15.7% reported a decrease in platelet count.
Hexavalent Vaccine Included in Pediatric Vaccination Program
The DTaP-IPV-Hib-HepB vaccine has safety profile consistent with licensed comparator vaccines and has been included in the federal Vaccines for Children program.
ACIP Updates Recommendations for Tdap Vaccination
Updated recommendations for the use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine have been developed by the Advisory Committee on Immunization Practices (ACIP).
ACIP: 2020 Child and Adolescent Immunization Schedule Updates
The ACIP has released an updated version of the child and adolescent immunization schedule for ages 18 years and younger in the United States.
ACIP: 2020 Adult Immunization Schedule Updates
The ACIP has released an updated version of the adult immunization schedule for ages 19 years and older in the United States.
Bivalent HPV Vaccine Induces Robust Serologic Response Nine Years Postvaccination
In addition to high antibody levels, factors including exposure to the human papillomavirus (HPV) and antibody avidity may be important and necessary to protect against infection.
ACIP: Updated Recommendations for Tdap Vaccination
ACIP has updated recommendations to allow for the use of the Tdap vaccine for the decennial tetanus and diphtheria toxoid booster.
Mandatory Vaccination Increases Prevalence of Vaccine Coverage
Mandatory vaccination is associated with increased vaccination coverage for measles and pertussis as well as reduced measles incidence in Europe.
Microbiologic Failure in the Setting of Clinical Cure of Bacterial Pneumonia
Microbiologic treatment failure was found to be independently associated with recurrent pneumonia or death among patients with bacterial pneumonia after clinical cure.
Mortality Risk Among Patients With Oropharynx Cancer Varies Based on HPV Status
For patients with oropharynx cancer, the rates of head and neck cancer mortality and competing mortality vary depending on HPV status.
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