Respiratory

Latest News

Respiratory Droplets From a Person Walking Downstairs Increases Risk for Infection

By

Estie Mermelstein, MSN, FNP-BC

Investigators conducted a study that compared the risk for infection from the dispersion of respiratory droplets from a person walking downstairs vs upstairs.

Interventions to Promote Physical Activity May Benefit Asthma Patients

Interventions that promote physical activity have significant benefits in terms of increasing physical activity, decreasing sedentary time, and improving quality of life in patients with asthma.

Combustion-Related Nitrogen Dioxide Contributes to Pediatric Asthma

Combustion-related nitrogen dioxide (NO2) accounted for 1.85 million new pediatric asthma cases worldwide in 2019.

Oral vs IV Antibiotics for Pseudomonas aeruginosa Infection in Patients With Cystic Fibrosis

By

Estie Mermelstein, MSN, FNP-BC

Researchers conducted a study to compare the effects of intravenous vs oral antibiotics therapy in patients with a pulmonary infection caused by Pseudomonas aeruginosa secondary to cystic fibrosis.

The Role of Lactate Dehydrogenase to Albumin Ratio in Patients With Lower Respiratory Tract Infection

By

Jessica Nye, PhD

Researchers conducted a study to determine whether the lactate dehydrogenase to albumin ratio is an independent prognostic factor predictive of in-hospital mortality in patients with lower respiratory tract infection.

SGLT2i Use Has Lower Pneumonia Risk vs DPP4i in Type 2 Diabetes

By

Colby Stong

People with type 2 diabetes have a high risk of catching pneumonia. Researchers sought to discover which drugs made people more susceptible to this serious lung infection.

Regular Physical Activity Can Help Cut Pneumonia Risk

Regular physical activity is associated with lower pneumonia risk in the general population.

Efficacy of a Prolonged Infusion of Meropenem in Patients Hospitalized With Severe Pneumonia

By

Bradley van Paridon

Researchers conducted a study to determine whether a prolonged infusion time increases the efficacy of meropenem for the treatment of patients hospitalized with severe pneumonia.

Effects of β-Lactam Plus Doxycycline in Older Adults With Community-Acquired Pneumonia

By

Jessica Nye, PhD

Researchers conducted a study to assess the effect of doxycycline treatment on the risk for 30 and 90-day all-cause mortality in older adults hospitalized with community-acquired pneumonia.

Shorter, Low-Dose Amoxicillin Feasible for Pediatric Community-Acquired Pneumonia

Amoxicillin 35 to 50 mg/kg per day noninferior to 70 to 90 mg/kg per day; three days noninferior to seven days for duration.

Assessing Lung Function Using Peripheral O2 Saturation in Suspected Sepsis

By

Virginia A. Schad, PharmD, RPh

Can peripheral oxygen saturation levels be used instead of arterial blood gas analysis to calculate SOFA scores in patients with suspected sepsis?

Comparing Testing Methods for Latent Tuberculosis Among Diverse High-Risk Populations

By

Jessica Nye, PhD

Researchers assessed and compared 3 tests for latent tuberculosis infection among high-risk individuals in the US.

Exposure to Inhaled Corticosteroids Increases Risk for Nontuberculous Mycobacterial Lung Disease

By

Jessica Nye, PhD

Researchers conducted a meta-analysis to assess the risk for nontuberculous mycobacterial lung disease in patients who use inhaled corticosteroids.

Ethnic Disparities in Influenza-Associated Hospitalization and Death

By

Bryant Moeller

Analysis of 10 years of data revealed that racial and ethnic minorities experienced more adverse outcomes from severe influenza.

Outcomes of Neuraminidase, Endonuclease Inhibitors for the Treatment of Patients With Seasonal Influenza

By

Jessica Nye, PhD

Researchers conducted a systematic review and meta-analysis that compared outcomes of 4 antiviral agents for the treatment of patients with seasonal influenza.

Real-World Study Compares 2 Long-Acting β2-Agonists for Asthma Control

By

Bryant Moeller

A large, retrospective study compared the asthma control effectiveness of once-daily fluticasone furoate/vilanterol vs twice-daily budesonide/formoterol.

Combined Antibiotic Dry Powder Inhaler Offers Some Relief for Pulmonary TB

By

Brandon May

A recent trial compared the efficacy of standard oral therapy for pulmonary TB with a dry powder inhaler containing fixed doses of isoniazid, rifampicin, pyrazinamide, and levofloxacin.

Omadacycline Gets Orphan Drug Status for Nontuberculous Mycobacteria Infections

By

Brian Park, PharmD

The Company is evaluating oral omadacycline in approximately 75 adults with NTM pulmonary disease caused by MABc in an ongoing phase 2b study.

FDA Grants Fast Track Status to mRNA Respiratory Syncytial Virus Vaccine Candidate

By

Brian Park, PharmD

mRNA-1345 is a vaccine candidate against RSV that utilizes the same lipid nanoparticle as Moderna’s authorized COVID-19 vaccine.

No Benefit From Continuous Positive Airway Pressure After Elective Major Intraperitoneal Surgery

By

Jessica Nye, PhD

Members of the PRISM trial group investigated whether CPAP administered immediately after major abdominal surgery could prevent postoperative morbidity.