Whole Genome Sequencing Use in Predicting TB Resistance
Whole genome sequencing of M tuberculosis isolates can identify complete drug susceptibility profiles, allowing precise treatment in early TB infection.
Respiratory
Respiratory
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SynGEM Intranasal Vaccine for RSV Generates Durable Immune Response
SynGEM, an intranasal subunit vaccine that introduces the respiratory syncytial virus (RSV), has demonstrated efficacy in actuating lasting immune responses in humans.
Effect of Vitamin D Supplementation on Sputum Culture Conversion in Tuberculosis
In a subgroup of patients with multidrug-resistant tuberculosis, vitamin D supplementation accelerated sputum culture conversion.
Diagnosing Chronic Pulmonary Aspergillosis in Treated Pulmonary TB
Chronic pulmonary aspergillosis complicates treated pulmonary tuberculosis frequently.
Infection and Infarction: Cause and Effect?
Investigators sought to confirm long-standing hypotheses that acute infections can lead to myocardial infarction.
Diagnostic-Driven Approach to Treatment of Invasive Aspergillosis Effective
Treatment for invasive aspergillosis using diagnostic-driven approach of voriconazole, galactomannan testing led to better outcomes than empiric therapy.
Experimental TB Vaccine Is in Phase 1 Human Trial
A freeze-dried, temperature-stable, experimental tuberculosis vaccine candidate has entered a phase 1 human clinical trial.
Tuberculosis Detection May Be Affected by Blood Draw Method
Tuberculosis screening results may differ depending on blood draw methods.
Deep Learning Algorithm Outperforms Physicians Detecting Active Pulmonary TB
A deep-learning algorithm performed better than radiologists at detecting active pulmonary tuberculosis on chest radiographs.
Pyrosequencing Detects Tuberculosis Drug Resistance and Improves Management
Pyrosequencing may benefit clinical decision making and reduce time to start of effective treatment in patients with drug-resistant tuberculosis.
11th Child Dies in Adenovirus Outbreak at N.J. Care Facility
Child was among 34 youngsters at the care facility who became ill between Sept. 26 and Nov. 12.
Wildfire Respiratory Protection and Preventing Breathing Problems
The California wildfires are on just about everyone’s mind. If you practice near the affected areas or in another location prone to wildfires, take into consideration these wildfire respiratory protection instructions.
Efficacy of M72/AS01E Tuberculosis Vaccine in Phase 2b Controlled Trials
The M72/AS01E tuberculosis vaccine provided 54.0% protection for M tuberculosis-infected adults against active pulmonary tuberculosis disease.
Stratifying by Severity May Allow Shorter TB Tx Regimens
Stratifying tuberculosis patients by disease severity may enable shorter treatment regimens.
Homeopathy No Better Than Placebo for Respiratory Infections in Children
When compared to placebo, homeopathic medicines do not provide any additional benefit to children with acute respiratory tract infections.
Seven Dead in Adenovirus Outbreak at Care Facility
Seven deaths, at least six of which were of children, have been associated with a current outbreak of infections with adenovirus serotype 7 at a New Jersey facility.
Limited Evidence for OTC Preps to Treat Nasal Symptoms of Colds
Limited evidence is available for OTC treatments for nasal symptoms of the common cold.
Severity of Acute Respiratory Infections in Children Affected by Viral Etiology
Viral etiology plays a significant role in symptom severity in children with acute respiratory infections, and associated with an enhanced risk for acquiring subsequent acute respiratory infections.
Prescribing Antibiotics Shortens Telemedicine Visits for Respiratory Tract Infections
These findings may highlight physician difficulty explaining to patients why antibiotics are not required.
New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance
Xpert MTB/RIF may be helpful for confirming a diagnosis of extrapulmonary tuberculosis and can accurately detect resistance to rifampicin.
Patient Develops Rare Extrapulmonary Manifestation of Tuberculosis
The patient, a 42-year-old female with systemic lupus erythematosus treated with mycophenolate mofetil and prednisone, reported swelling and pain in the fifth finger of her left hand for about 1-week.
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