Whole Genome Sequencing Use in Predicting TB Resistance
Whole genome sequencing of M tuberculosis isolates can identify complete drug susceptibility profiles, allowing precise treatment in early TB infection.
Respiratory
Respiratory
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New Scale Helps Identify More Serious Cases of Mononucleosis
Scale identifies college students at increased risk for corticosteroid Rx, chronic fatigue syndrome
Internet-Based Communication Training May Reduce Antibiotic Prescribing in RTIs
An internet-based training program designed to enhance communication skills in C-reactive protein point of care testing may be helpful in reducing long-term antibiotic prescribing in respiratory tract infections.
Cytomegalovirus Linked to Faster Progression of Cystic Fibrosis
Faster progression to end-stage lung disease observed among patients with CMV IgG positivity
QuantiFERON-TB Gold-Plus Performance in Children With Confirmed Tuberculosis
The new interferon-gamma release assay QuantiFERON-TB Gold Plus had good sensitivity in children with pulmonary tuberculosis.
Building a Tuberculosis-Free World
The first-ever UN High-Level Meeting on tuberculosis, in September 2018, resolved that ending the disease is a global priority.
Nasopharyngeal Microbiota Could Help Diagnose Pediatric LRTIs
Nasopharyngeal microbiota seem to serve as a valid proxy for lower respiratory tract microbiota in lower respiratory tract infections in children.
Bronchiolitis Hospitalization in Infancy Predicts More Admissions
More than one in five infants with a bronchiolitis hospital admission will have a subsequent respiratory-related hospital admission by age 5 years.
SynGEM Intranasal Vaccine for RSV Generates Durable Immune Response
SynGEM, an intranasal subunit vaccine that introduces the respiratory syncytial virus (RSV), has demonstrated efficacy in actuating lasting immune responses in humans.
Effect of Vitamin D Supplementation on Sputum Culture Conversion in Tuberculosis
In a subgroup of patients with multidrug-resistant tuberculosis, vitamin D supplementation accelerated sputum culture conversion.
Diagnosing Chronic Pulmonary Aspergillosis in Treated Pulmonary TB
Chronic pulmonary aspergillosis complicates treated pulmonary tuberculosis frequently.
Infection and Infarction: Cause and Effect?
Investigators sought to confirm long-standing hypotheses that acute infections can lead to myocardial infarction.
Diagnostic-Driven Approach to Treatment of Invasive Aspergillosis Effective
Treatment for invasive aspergillosis using diagnostic-driven approach of voriconazole, galactomannan testing led to better outcomes than empiric therapy.
Experimental TB Vaccine Is in Phase 1 Human Trial
A freeze-dried, temperature-stable, experimental tuberculosis vaccine candidate has entered a phase 1 human clinical trial.
Tuberculosis Detection May Be Affected by Blood Draw Method
Tuberculosis screening results may differ depending on blood draw methods.
Deep Learning Algorithm Outperforms Physicians Detecting Active Pulmonary TB
A deep-learning algorithm performed better than radiologists at detecting active pulmonary tuberculosis on chest radiographs.
Pyrosequencing Detects Tuberculosis Drug Resistance and Improves Management
Pyrosequencing may benefit clinical decision making and reduce time to start of effective treatment in patients with drug-resistant tuberculosis.
11th Child Dies in Adenovirus Outbreak at N.J. Care Facility
Child was among 34 youngsters at the care facility who became ill between Sept. 26 and Nov. 12.
Wildfire Respiratory Protection and Preventing Breathing Problems
The California wildfires are on just about everyone’s mind. If you practice near the affected areas or in another location prone to wildfires, take into consideration these wildfire respiratory protection instructions.
Efficacy of M72/AS01E Tuberculosis Vaccine in Phase 2b Controlled Trials
The M72/AS01E tuberculosis vaccine provided 54.0% protection for M tuberculosis-infected adults against active pulmonary tuberculosis disease.
Stratifying by Severity May Allow Shorter TB Tx Regimens
Stratifying tuberculosis patients by disease severity may enable shorter treatment regimens.
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