Respiratory

Latest News

Risk of Aortic Aneurysm, Dissection With Fluoroquinolones Examined

By

Cassandra Pardini, PharmD

The observational study aimed to determine the association between fluoroquinolone use and the risk of aortic aneurysm or aortic dissection while taking into account potential confounding.

Respiratory, Lung Cancer Death Up Even With Low-Intensity Smoking

Current low-intensity smokers have an increased risk for respiratory and lung cancer mortality.

H1N1 Vaccine Exposure During Fetal Life Not Associated With Autism Spectrum Disorder

By

Sweta Gupta

Fetal exposure to the H1N1 vaccine is not associated with an increased risk for autism spectrum disorder or autistic disorder in children.

Evaluating Replication Competence and Immune Response to Adenovirus Type 7 In Pediatric Populations

By

Bradley van Paridon

Researchers compared HAdV-3 with HAdV-7 replication kinetics and host response in ex vivo human lung tissue cultures.

High Rates of Acute Cardiovascular Events Among Hospitalized Patients With Influenza

By

Brandon May

The rate of acute cardiovascular events was found to be high in adults hospitalized with influenza.

In-Hospital Heart Failure Deaths Down With Routine Vaccinations

For patients with heart failure, influenza and pneumococcal vaccinations are associated with lower in-hospital mortality.

Pimodivir Influenza Development Program Discontinued

By

Brian Park, PharmD

The efficacy and safety of pimodivir, an inhibitor of influenza virus polymerase basic protein 2, was being investigated in two phase 3 studies.

Asthma Does Not Appear to Affect COVID-19 Hospitalization Outcomes

By

Bryant Moeller

Younger patients with asthma who were hospitalized with COVID-19 did not have worse outcomes than patients hospitalized with COVID-19 without asthma.

Invasive Potential of Pneumococcal Serotypes Post-PCV13 Implementation

By

Bradley van Paridon

The aim of this study was to evaluate the invasive disease potential of non-PCV13 serotypes after implementation of this vaccine.

Honey Beats Usual Care for Upper Respiratory Tract Infections

For upper respiratory tract infections (URTIs), honey seems superior to usual care.

Safety, Immunogenicity of Investigational Inactivated Whole-Virus COVID-19 Vaccine

By

Marissa Purdy

An investigational inactivated whole-virus COVID-19 vaccine has demonstrated safety and immunogenicity, according to an interim analysis.

ACIP: Influenza Vaccination Recommendations for 2020-2021

By

Diana Ernst, RPh

Influenza vaccination should occur by the end of October, if possible.

CFHealthHub Criteria May Be Useful to Diagnose P Aeruginosa in Cystic Fibrosis

By

Virginia A. Schad, PharmD, RPh

Preliminary evidence suggests that the CFHealthHub criteria are valid and useful in diagnosing chronic Pseudomonas aeruginosa in adults with cystic fibrosis.

Early Data Suggest Tradipitant May Accelerate Recovery in COVID-19 Pneumonia

By

Brian Park, PharmD

The ODYSSEY study is evaluating the efficacy and safety of tradipitant in adults with neurogenic inflammation of the lung secondary to COVID-19 infection.

Underutilization of Influenza Vaccination in Populations at High-Risk for Complications

By

Jessica Nye, PhD

Influenza vaccinations were found to be underutilized among groups who are considered to be at high risk for complications from infection.

Vitamin D Supplementation Does Not Lower Risk for Primary Tuberculosis Infection

By

Sweta Gupta

A team of investigators conducted a phase 3, double-blind trial to assess the impact of vitamin D supplementation on risk of tuberculosis infection in public schoolchildren in Mongolia.

Legionella Bacteria Forces CDC Office Closures

The U.S. Centers for Disease Control and Prevention informed employees that office space it rents in the Atlanta area would be closed after Legionella, the bacteria that causes legionnaires disease, was found in the buildings.

Subclinical Bacteria in Home May Contribute to Poor Asthma Control

By

Brandon May

Subclinical bacteria in the home environment likely influence the airway microbiome and contribute to poor asthma control in patients with refractory asthma.

Sisunatovir Fast-Tracked for Serious RSV Infection

By

Brian Park, PharmD

Sisunatovir is an orally administered RSV fusion inhibitor that binds to RSV-F protein on the viral surface inhibiting RSV replication.

ICD-9 Diagnosis Codes May Not Accurately Capture Pneumonia Etiology

By

Sheila Jacobs

ICD-9 organism-specific administrative codes for pneumonia appear to underestimate the prevalence of specific disease-associated pathogens in hospitalized patients.