Respiratory

Latest News

Comparing Testing Methods for Latent Tuberculosis Among Diverse High-Risk Populations

By

Jessica Nye, PhD

Researchers assessed and compared 3 tests for latent tuberculosis infection among high-risk individuals in the US.

Exposure to Inhaled Corticosteroids Increases Risk for Nontuberculous Mycobacterial Lung Disease

By

Jessica Nye, PhD

Researchers conducted a meta-analysis to assess the risk for nontuberculous mycobacterial lung disease in patients who use inhaled corticosteroids.

Ethnic Disparities in Influenza-Associated Hospitalization and Death

By

Bryant Moeller

Analysis of 10 years of data revealed that racial and ethnic minorities experienced more adverse outcomes from severe influenza.

Outcomes of Neuraminidase, Endonuclease Inhibitors for the Treatment of Patients With Seasonal Influenza

By

Jessica Nye, PhD

Researchers conducted a systematic review and meta-analysis that compared outcomes of 4 antiviral agents for the treatment of patients with seasonal influenza.

Real-World Study Compares 2 Long-Acting β2-Agonists for Asthma Control

By

Bryant Moeller

A large, retrospective study compared the asthma control effectiveness of once-daily fluticasone furoate/vilanterol vs twice-daily budesonide/formoterol.

Combined Antibiotic Dry Powder Inhaler Offers Some Relief for Pulmonary TB

By

Brandon May

A recent trial compared the efficacy of standard oral therapy for pulmonary TB with a dry powder inhaler containing fixed doses of isoniazid, rifampicin, pyrazinamide, and levofloxacin.

Omadacycline Gets Orphan Drug Status for Nontuberculous Mycobacteria Infections

By

Brian Park, PharmD

The Company is evaluating oral omadacycline in approximately 75 adults with NTM pulmonary disease caused by MABc in an ongoing phase 2b study.

FDA Grants Fast Track Status to mRNA Respiratory Syncytial Virus Vaccine Candidate

By

Brian Park, PharmD

mRNA-1345 is a vaccine candidate against RSV that utilizes the same lipid nanoparticle as Moderna’s authorized COVID-19 vaccine.

No Benefit From Continuous Positive Airway Pressure After Elective Major Intraperitoneal Surgery

By

Jessica Nye, PhD

Members of the PRISM trial group investigated whether CPAP administered immediately after major abdominal surgery could prevent postoperative morbidity.

Respiratory Virus Detections, Antibiotic Prescribing Rates Decreased ‪‬During COVID-19 Pandemic

By

Sweta Gupta

The researchers tested their hypothesis that a decrease in respiratory virus incidence would be associated with a reduction in inappropriate ambulatory antibiotic orders.

Sex Differences in Mortality After Tuberculosis Treatment

By

Sweta Gupta

Researchers studied patients with pulmonary tuberculosis to better understand the impact of sex on mortality and sputum microbiological status after treatment initiation.

Effectiveness of Antipseudomonal Antibiotics for Pulmonary Exacerbation of Cystic Fibrosis

By

Jessica Nye, PhD

Researchers compared clinical outcomes of single vs double antipseudomonal antibiotics used to treat pulmonary exacerbations in patients with cystic fibrosis.

Pneumococcal Vaccine Associated With Steep Decline in Antibiotic Use Among Young Children in Israel

By

Sweta Gupta

Researchers compared trends in antibiotic prescription rates during the period preceding the pneumococcal conjugate vaccine (PCV), as well as the early and late PCV periods, among Jewish vs Bedouin children.

Extended Amoxicillin-Clavulanate Not Curative for Suspected Protracted Bacterial Bronchitis Among Children

By

Jessica Nye, PhD

Researchers conducted a randomized controlled trial to determine the effectiveness of a 4-week course of oral amoxicillin-clavulanate in children with suspected protracted bacterial bronchitis.

Study Finds 4-Month Tuberculosis Treatment Noninferior to Standard of Care

By

Sweta Gupta

Researchers conducted a phase 3 trial to ascertain whether treatment regimens including rifapentine with or without moxifloxacin can provide a lasting cure for drug-susceptible pulmonary tuberculosis in 4 months vs 6 months of standard therapy.

Prevalence of E-Cigarette Use High Among US Students

Current electronic cigarette use, frequent use, and flavored e-cigarette use is high among high school and middle school students in the United States.

FDA Approves 20-Valent Pneumococcal Conjugate Vaccine Prevnar 20

By

Diana Ernst, RPh

The vaccine contains capsular polysaccharide conjugates for 7 additional serotypes (8, 10A, 11A, 12F, 15B, 22F and 33F) that cause invasive pneumococcal disease.

Suvratoxumab Not Effective at Reducing Staphylococcus aureus Pneumonia in the Intensive Care Unit Setting

By

Jessica Nye, PhD

Researchers report findings from SAATELLITE, a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial that assessed the safety and efficacy of suvratoxumab for Staphylococcus aureus pneumonia.

Lower Respiratory Specimens Optimal for Accurate Psittacosis Detection

By

Estie Mermelstein, MSN, FNP-BC

A case study published in the Morbidity and Mortality Weekly Report describes an outbreak of Chlamydia psittaci among works at chicken slaughter plants in the southeast United States.

Low-Dose Amikacin as Alternative Treatment for Multidrug-Resistant Tuberculosis

By

Joyce Lee, PharmD, RPh

A retrospective cohort study was conducted to assess tolerability, side effects, and outcomes following treatment with low-dose amikacin in patients with multidrug-resistant tuberculosis.