Endogenous Klebsiella pneumoniae Cases Increasing in Australia

HealthDay News — Increasing trends of endogenous Klebsiella pneumoniae endophthalmitis (EKPE) have been reported in Australia, according to research published online August 26 in Clinical & Experimental Ophthalmology.

Capucine Odouard, MBBS, from Sydney Hospital & Sydney Eye Hospital, and colleagues conducted a retrospective observational case study and case series involving 4 cases of EKPE.

The researchers noted rising trends of EKPE in major centers in Australia. From January 2011 to December 2015, 6 eyes of 4 patients with EKPE were reported (bilateral involvement for 2 patients). Systemic symptoms were reported up to 10 days before ocular symptoms. In all cases the source of sepsis was a hepatic abscess. Two of the patients had diabetes mellitus. On presentation, 5 eyes had hypopyon panuveitis. Vitrectomy was performed on all eyes. Enucleation after globe perforation was performed for the patient with the most delayed presentation. In 1 patient with bilateral EKPE, the final best corrected visual acuity (BCVA) was light perception only; the other 3 patients had BCVA in at least 1 eye of at least 6/24.

“EKPE is an emerging condition in Australia. Although rare, EKPE is a sight-threatening and potentially life-threatening emergency that can initially present to ophthalmologists,” the authors write. “One should suspect EKPE in septic patients with a B-scan showing a vitreous or retinal abscess.”

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  1. Odouard C, Ong D, Shah PR, et al. Rising trends of endogenous Klebsiella pneumoniae endophthalmitis in Australia. Clin Exp Ophthalmol. 2016; doi: 10.1111/ceo.12827