Plant-Based Vaccine Manufacturing for Influenza, Implications for Future Vaccines
An emerging body of research highlights plant-based vaccine manufacturing as a potential solution to risks posed by traditional egg-based manufacturing.
Influenza
Influenza
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Are Higher Neuraminidase Antibody Concentrations Associated With Decreased Disease Severity in Individuals With Influenza?
Immunity against neuraminidase is important to consider in development of therapeutics and influenza vaccines with improved efficacy and protection.
Ethnic Disparities in Influenza-Associated Hospitalization and Death
Analysis of 10 years of data revealed that racial and ethnic minorities experienced more adverse outcomes from severe influenza.
Outcomes of Neuraminidase, Endonuclease Inhibitors for the Treatment of Patients With Seasonal Influenza
Researchers conducted a systematic review and meta-analysis that compared outcomes of 4 antiviral agents for the treatment of patients with seasonal influenza.
Exposure to Flu-Like Illness in Doctor’s Office Ups Odds of Return Visit
Patients exposed to influenza-like illness in the medical office setting are more likely to return with a similar illness in the following two weeks.
RSV and Parainfluenza Increase Hospitalization Risk in HIV-Exposed Infants
As HIV-exposed, uninfected infants have higher rates of morbidity and mortality than HIV-unexposed uninfected infants, a study was conducted to analyze whether particular infections or immune responses contribute to hospitalization.
Respiratory Virus Detections, Antibiotic Prescribing Rates Decreased During COVID-19 Pandemic
The researchers tested their hypothesis that a decrease in respiratory virus incidence would be associated with a reduction in inappropriate ambulatory antibiotic orders.
Viruses Causing Acute Respiratory Illness During the 2018/19 Influenza Season in Washington
A team of investigators sought to estimate the burden of acute respiratory illness in ambulatory care settings for 12 respiratory viruses in Washington state during the 2018-2019 influenza season.
Flu Vaccine Provides Some Protection Against Hospitalization in Children
Investigators conducted a systematic review and meta-analysis of 37 studies that used a test-negative design to evaluate IVE against influenza-associated hospitalization in children.
Low-Dose Intradermal Flu Vaccine as Effective as Standard Intramuscular Dose
Investigators compared the immunogenicity and safety of the influenza vaccine of different intradermal vaccine doses with a standard intramuscular dose.
Patients of Female Doctors More Likely to Receive Flu Vaccine
Researchers used Medicare claims data to estimate differences in influenza vaccination rates among patients of female vs male physicians.
Repeated Influenza Vaccination Could Reduce Effectiveness
Researchers assessed the impact on pooled adjusted end-season vaccine effectiveness estimates from outpatient test-negative design studies.
Flucelvax Quadrivalent Approval Expanded to Include Younger Patients
Flucelvax Quadrivalent is a subunit influenza vaccine manufactured using cell derived candidate vaccine viruses; it does not contain egg proteins or antibiotics.
Trivalent Adjuvanted, High-Dose Inactivated Influenza Vaccines Safe for Older Adults
Researchers compared safety, reactogenicity, and changes in Health-Related Quality of Life scores of aIIV3 vs HD-IIV3 flu vaccines in older adults.
Burden of Noninfluenza Respiratory Virus Infection Considerable
Researchers analyzed pooled patient data from 2 hospital-based respiratory virus surveillance cohorts to assess the burden of noninfluenza respiratory virus (NIRV) infection.
COVID-19 Precautions Cut Transmission of Other Common Viruses
Researchers compared respiratory viral infections other than severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2020 to corresponding periods in the previous 5 years.
Flu Vaccine Rate Expected to Reach All-Time High for 2020-2021 Season
In December 2020, researchers conducted a survey of 1027 adults to determine percentage of those receiving, or intending to receive, influenza vaccination.
Laws Encouraging Hospital Workers to Vaccinate Reduce Influenza Mortality Rates
The objective of this quasi-experimental observational study was to measure the effect of states’ hospital worker influenza vaccination laws on pneumonia and influenza mortality.
Increasing Age, Immunosuppression Associated With Less Protection By Influenza Vaccine
Study authors evaluated influenza-vaccinated patients hospitalized with an influenza-like illness to identify characteristics associated with being at increased risk for hospitalization with influenza.
AS03-Adjuvanted Flu Vaccine Increases Narcolepsy Incidence, Clinically Similar to Sporadic Cases
The AS03-adjuvanted H1N1 influenza vaccine was linked to an increased narcolepsy incidence, but this narcolepsy did not clinically differ significantly from sporadic cases.
Untreated Obstructive Sleep Apnea Linked to More Influenza Hospitalizations
There may be increased hospitalization risk from influenza infection in patients with obstructive sleep apnea who do not use continuous positive airway pressure.
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