H1N1/H3N2 Influenza Variants With Reduced Susceptibility to Baloxavir
The PA-I38 mutations were noted frequently in influenza A/H3N2 viruses compared with A/H1N1pdm or influenza B viruses.
Influenza
Influenza
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Cell-Cultured Superior to Egg-Derived Influenza Vaccine
Cell-cultured quadrivalent influenza vaccines may have greater effectiveness compared with standard, egg-derived quadrivalent influenza vaccines.
Influenza Vaccine Not Linked to Decrease in Hospitalizations or Mortality Among Elderly
Targeting the elderly (individuals aged 65 years) for influenza vaccination may not decrease hospitalization or mortality rates in this population.
Poorer Clinical Outcomes in COVID-19 Driven by Comorbidities
In laboratory-confirmed cases of COVID-19, patients with any comorbidities have experienced poorer clinical outcomes compared with those without comorbidities.
COVID-19 vs H1N1 Influenza: A Clinical Characteristic Comparison
Hospitalized patients withCOVID-19 had higher proportions of nonproductive cough, fatigue, and gastrointestinal symptoms as well as lower severity of illness scores compared with patients with H1N1 influenza.
Contribution of Leaky Vaccine Effect to Influenza Effectiveness
The observed intra-seasonal decreases of measured influenza vaccine effectiveness was only partially accounted for by leaky vaccine bias.
Face Masks Offer Slight Protective Effect From Flu-Like Illness
Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact.
Frequency and Factors Associated With Hospital Readmissions Due to Influenza
Hospitalization due to influenza leads to a high likelihood of readmission within 30 days and 1 year with cardiovascular, respiratory, and infectious etiologies being the most common.
Universal FLU-v Influenza Vaccine, Immunogenic and Warrants Further Testing
The adjuvanted, broad-spectrum influenza vaccine FLU-v was found to be immunogenic and merits phase 3 development to explore efficacy.
Does Seasonal Influenza Vaccine Increase Risk for Guillain-Barré Syndrome?
Researchers determined the risk for Guillain-Barré Syndrome following seasonal influenza vaccination in a real-world study.
FDA to Review Baloxavir for Pediatric Use, Postexposure Prophylaxis of Influenza
Baloxavir inhibits the endonuclease activity of the polymerase acidic protein resulting in inhibition of influenza virus replication.
Addressing Parents’ Concerns Improves Influenza Immunization Rates
Implementation of an influenza immunization program increased vaccinations rates from 44% to 57% the following year.
Neuraminidase Inhibitor Treatment for Influenza B-Related Pneumonia
Early neuraminidase inhibitor therapy may result in better outcomes in patients hospitalized with influenza B-related pneumonia.
Fluad Quadrivalent Influenza Vaccine Approved for Older Adults
The FDA has approved Fluad Quadrivalent for active immunization in patients 65 years of age and older against influenza disease caused by influenza virus subtypes A and types B contained in the vaccine.
Oseltamivir Not Linked to Increase Risk for Neuropsychiatric Events
No difference was seen in the risk for serious neuropsychiatric events in patients who received oseltamivir in the 30 days after influenza diagnosis compared with those who did not.
Evaluation of Trivalent vs Quadrivalent Inactivated Vaccine for Influenza B
Despite the higher effectiveness of the quadrivalent inactivated influenza vaccine against the added B virus lineage, trivalent inactivated influenza vaccine.
Antibiotic and Antiviral Combination to Treat Influenza
Compared with patients prescribed only an antiviral, patients who are prescribed both an antiviral and antibiotic have a lower risk for 3-day respiratory hospitalization.
Influenza Vaccine Effectiveness for 2019-2020 Season Assessed
The CDC continues to recommend influenza vaccination as the best method of protection while the viruses are circulating in the community.
Does Race Affect Peripheral Tfh Cells After Influenza Vaccination Among PLWHIV?
Black people who are HIV-positive may have a decreased ratio of influenza-specific IgG vs IgM after influenza vaccination.
Double-Dose Influenza Vaccine Doses May Not Benefit Pregnant Women With HIV
A double-dose of inactivated influenza vaccine may not increase the immunogenicity of the vaccine among pregnant women with HIV.
Audenz, an H5N1 Influenza Vaccine, Gets FDA Approval
The FDA has approved influenza A [H5N1] monovalent vaccine for active immunization for the prevention of disease in patients 6 months of age and older at increased risk of exposure to the influenza A H5N1 virus subtype contained in the vaccine.
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