Influenza

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N95 Respirators vs Surgical Masks for Protection Against Viral Respiratory Illnesses

By

Bradley van Paridon

Researchers conducted a meta-analysis to determine the effectiveness of N95 respirators vs surgical masks in protecting against viral respiratory illness transmission.

Influenza Infection Linked to Long-Term Increased Risk for Parkinson Disease

By

Amit Akirov, MD

Researchers sought to examine whether prior influenza or other infections are associated with Parkinson disease more than 10 years after infection.

Efficacy of a Cell-Based Quadrivalent Inactivated Influenza Vaccine (IIV4c) in Children, Adolescents

By

Estie Mermelstein, MSN, FNP-BC

Investigators conducted a study to assess the efficacy of a cell-based quadrivalent inactivated influenza vaccine (IIV4c) in preventing influenza virus infection in adolescents and children.

Prevnar 20 Coadministered With Flu Vaccine Immunogenic, Safe in Older Adults

By

Brian Park, PharmD

The randomized, double-blind trial enrolled a total of 1796 participants, of which 1727 completed the study.

Prevalence and Outcomes of Patients With COVID-19 and Influenza Co-Infection

By

Jessica Nye, PhD

Researchers conducted a study that compared the prevalence of COVID-19 with influenza co-infection among the general population vs hospitalized patients, as well as outcomes associated with both infections vs COVID-19 alone.

Outcomes of SARS-CoV-2 vs Other Respiratory Infections in Solid Organ Transplant Recipients

By

Infectious Disease Advisor Contributing Writer

Study finds that patients with SARS-CoV-2 infection who are solid organ transplant recipients are at increased risk for intensive care unit admission, invasive mechanical ventilation, and mortality.

Relative Effectiveness of Egg- vs Cell-Based Quadrivalent Influenza Vaccines in Periods of Increased Influenza Activity

By

Jessica Nye, PhD

Researchers conducted a study to compare the relative effectiveness of egg-based vs cell-based quadrivalent influenza vaccines in decreasing hospitalizations and emergency department admissions during influenza season.

Association Between Antimicrobial-Resistant Pathogens and Seasonal Influenza Infection Rates

By

Jessica Nye, PhD

Researchers sought to determine whether there is a correlation between antimicrobial-resistant pathogens and influenza infection rates that occur during influenza season in ambulatory and inpatient settings.

Are Higher Neuraminidase Antibody Concentrations Associated With Decreased Disease Severity in Individuals With Influenza?

By

Estie Mermelstein, MSN, FNP-BC

Immunity against neuraminidase is important to consider in development of therapeutics and influenza vaccines with improved efficacy and protection.

Ethnic Disparities in Influenza-Associated Hospitalization and Death

By

Bryant Moeller

Analysis of 10 years of data revealed that racial and ethnic minorities experienced more adverse outcomes from severe influenza.

Outcomes of Neuraminidase, Endonuclease Inhibitors for the Treatment of Patients With Seasonal Influenza

By

Jessica Nye, PhD

Researchers conducted a systematic review and meta-analysis that compared outcomes of 4 antiviral agents for the treatment of patients with seasonal influenza.

Exposure to Flu-Like Illness in Doctor’s Office Ups Odds of Return Visit

Patients exposed to influenza-like illness in the medical office setting are more likely to return with a similar illness in the following two weeks.

RSV and Parainfluenza Increase Hospitalization Risk in HIV-Exposed Infants

By

Estie Mermelstein, MSN, FNP-BC

As HIV-exposed, uninfected infants have higher rates of morbidity and mortality than HIV-unexposed uninfected infants, a study was conducted to analyze whether particular infections or immune responses contribute to hospitalization.

Respiratory Virus Detections, Antibiotic Prescribing Rates Decreased ‪‬During COVID-19 Pandemic

By

Sweta Gupta

The researchers tested their hypothesis that a decrease in respiratory virus incidence would be associated with a reduction in inappropriate ambulatory antibiotic orders.

Viruses Causing Acute Respiratory Illness During the 2018/19 Influenza Season in Washington

By

Sweta Gupta

A team of investigators sought to estimate the burden of acute respiratory illness in ambulatory care settings for 12 respiratory viruses in Washington state during the 2018-2019 influenza season.

Flu Vaccine Provides Some Protection Against Hospitalization in Children

By

Sweta Gupta

Investigators conducted a systematic review and meta-analysis of 37 studies that used a test-negative design to evaluate IVE against influenza-associated hospitalization in children.

Low-Dose Intradermal Flu Vaccine as Effective as Standard Intramuscular Dose

By

Sweta Gupta

Investigators compared the immunogenicity and safety of the influenza vaccine of different intradermal vaccine doses with a standard intramuscular dose.

Patients of Female Doctors More Likely to Receive Flu Vaccine

Researchers used Medicare claims data to estimate differences in influenza vaccination rates among patients of female vs male physicians.

Repeated Influenza Vaccination Could Reduce Effectiveness

By

Bradley van Paridon

Researchers assessed the impact on pooled adjusted end-season vaccine effectiveness estimates from outpatient test-negative design studies.

Flucelvax Quadrivalent Approval Expanded to Include Younger Patients

By

Brian Park, PharmD

Flucelvax Quadrivalent is a subunit influenza vaccine manufactured using cell derived candidate vaccine viruses; it does not contain egg proteins or antibiotics.