Pneumonia prevention interventions such as proper oral care, head-of-bed elevation, and incentive spirometry, are not being provided to most patients outside the ICU, leading to greater than two-thirds of hospital-acquired pneumonia.
Researchers conducted a study to determine whether a prolonged infusion time increases the efficacy of meropenem for the treatment of patients hospitalized with severe pneumonia.
Researchers conducted a study to assess the effect of doxycycline treatment on the risk for 30 and 90-day all-cause mortality in older adults hospitalized with community-acquired pneumonia.
Researchers conducted a study to determine the association between the detection of bacteria in the upper respiratory tract and the risk for acute lower respiratory tract infection in young children.
In this fifth update to the living guidelines on drugs for the treatment of COVID-19, the World Health Organization analyzed results of clinical trials that assessed the effects of casirivimab-imdevimab and corticosteroids in patients with severe and non-severe disease.
Bacterial superinfection at time of intubation occurred in <25 percent of patients; reduced antibiotic use seen with bronchoalveolar lavage-based management versus current guidelines.
The study found prenatal exposure to carbon monoxide in household air pollution was a risk factor for early pneumonia, a leading global cause of death for children younger than 5 years.
Members of the PRISM trial group investigated whether CPAP administered immediately after major abdominal surgery could prevent postoperative morbidity.
Investigators conducted a quasi-experimental, retrospective study of adult patients with COVID-19 pneumonia to evaluate antibiotic use for community-acquired bacterial pneumonia following the release of guidelines.
Researchers compared trends in antibiotic prescription rates during the period preceding the pneumococcal conjugate vaccine (PCV), as well as the early and late PCV periods, among Jewish vs Bedouin children.
Researchers assessed antibiotic de-escalation practices across hospitals and their associations with outcomes in hospitalized patients with pneumonia who have negative cultures.
The vaccine contains capsular polysaccharide conjugates for 7 additional serotypes (8, 10A, 11A, 12F, 15B, 22F and 33F) that cause invasive pneumococcal disease.
