Machine-Learning Models Allow Early Detection of Sepsis in the NICU
Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent.
Sepsis
Sepsis
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How Preventable Is Sepsis-Associated Death in Hospitalized Adults?
While sepsis was the most common immediate cause of death at 6 US academic and community hospitals, most patients had severe chronic comorbidities.
Hospital-Onset MRSA Decreased From 2002 to 2015
Staphylococcus aureus infections are still a concern in the United States, despite a decline seen in hospital-onset MRSA infections since 2005.
Readmission for Patients With Sepsis Common and Costly
Readmission after sepsis hospitalization is common and is associated with considerable costs.
Machine Learning Model for Early Sepsis Risk Stratification
A new sepsis screening tool developed using machine learning was timelier and more discriminating than several benchmark screening tools.
Experimental Test May Quickly Diagnose Sepsis
A blood test that can quickly diagnose dangerous sepsis infections has been developed.
Pneumococcal Sepsis Risk Remains High in Children After Vaccination
The incidence of pneumococcal sepsis in children remained substantial after the introduction of the pneumococcal conjugate vaccine in Switzerland.
No Association Between LDL Cholesterol Levels and Risk for Sepsis
A low level of LDL cholesterol was initially associated with increased risk for sepsis and admission to the ICU.
Practices Vary in Treating Adult Staphylococcus aureus Bacteremia
Practices vary among clinicians in diagnosing and managing Staphylococcus aureus bacteremia in adults.
Use of Single-Family Rooms Reduces Incidence of Neonatal Sepsis
Using a single-family room setting significantly reduced neonatal sepsis and improved breastfeeding rates at discharge.
Corticosteroid Use Reduces 28-Day Mortality in Sepsis
The administration of corticosteroids in patients with sepsis may be associated with significant improvement in patient outcomes.
Scenario-Based Survey of Empiric Antibiotic Treatment Thresholds
80 to 90% pathogen coverage was acceptable to physicians as a threshold for managing patients with mild and severe sepsis from bacterial infections.
Worse Outcomes in Community-Acquired Pneumonia Linked to Higher FGF21 Levels
Patients diagnosed with community-acquired pneumonia with higher levels of fibroblast growth factor-21 may have higher mortality rates and longer hospitalizations.
Risk Factors for Repeat Surgery Identified in Septic Arthritis of the Hip
Investigators identified risk factors for repeat surgical intervention after initial arthrotomy for presumed septic arthritis of the hip.
Early IV Fluids Linked to Lower Mortality in Some Patients With Sepsis
Early administration of IV fluids by paramedics to patients with sepsis was linked with lower mortality, but only in patients with low initial systolic BP.
Emergency Department Overcrowding Associated With Delayed Antibiotics in Patients With Sepsis
Crowding in the emergency department was associated with the timely administration of antibiotics for patients presenting with sepsis.
Polymyxin B Hemoperfusion Does Not Change Mortality Rate in Septic Shock
For patients with septic shock and high circulating endotoxin levels, adding polymyxin B hemoperfusion treatment did not improve 28-day mortality rate.
Large Numbers of Negative Trial Results Impede Progress in Critical Care Medicine
Excessive numbers of negative clinical trials — many of which may be false-negative trials — are a major impediment to the advancement of critical care medicine.
Sepsis Can Affect Long Term Neurocognitive Dysfunction in Children With ALL
Sepsis associated with treatment for acute lymphoblastic leukemia in pediatric patients can affect long-term neurocognitive function.
Prehospital Advanced Life Support Shortens Antibiotic Wait Times in Sepsis
Antibiotic treatment started sooner in individuals with sepsis treated with advanced life support who did not have hypotension.
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