Among patients with sepsis and acute respiratory distress syndrome, administration of high-dose vitamin C via intravenous infusion does not significantly reduce organ failure.
The involvement of the biliary tract in bacteremia caused by Staphylococcus aureus may be more likely to develop in certain patients and aggressive treatment should be considered.
Bloodstream infections are common in patients who have received a solid organ transplants.
A shorter course of antibiotic treatment for uncomplicated gram-negative bloodstream infections appears to be as effective as long-course antibiotic treatment.
Cardiac implantable electronic device-related infective endocarditis is diagnosed in a third of patients with implantable device related infections.
When empirical antimicrobial therapy is initiated in patients with severe manifestations of sepsis, the sensitivity of blood cultures drawn shortly after treatment initiation is reduced.
About two-thirds of patients who survive hospitalization for sepsis have persistent elevation of inflammation and immunosuppression biomarker.
Data published in the Journal of the American College of Cardiology showed a high prevalence of definite infective endocarditis (IE) in patients with Enterococcus faecalis bacteremia (26%), suggesting that echocardiography should be considered in patients with E faecalis infection. A multicenter study using echocardiography was conducted from January 2014 to December 2016 in 344 consecutive…
The updated 1-hour sepsis care bundle is based on 2016 guidelines and recommends a specific set of treatments that should begin within 1 hour of sepsis recognition.
Breaches of recommended infection prevention practices have been identified in an outbreak of septic arthritis cases after intra-articular injections performed in a private outpatient facility.
Infants have a low probability of invasive bacterial infection if they are ≤60 days old with a fever by history only and have a normal urinalysis result.
The MALDI-TOF (Vitek MS, bioMérieux) assay demonstrated accuracy in the rapid identification of the most commonly isolated strains of Enterobacteriaceae, Staphylococcus aureus, and coagulase-negative staphylococci from colonies isolated from positive blood cultures, according to data presented at American Society of Microbiology (ASM) Microbe 2019, held June 20-24 in San Francisco, California. To test the accuracy…
Four distinct clinical phenotypes have been identified among patients with sepsis.
Staphylococcus aureus and Pseudomonas aeruginosa skin cultures may help to predictthe pathogens involved in bloodstream infections.
Computer-aided National Early Warning Score model model accurately predicts sepsis for emergency medical admissions.
People with culture-negative and culture-positive sepsis had similar characteristics and, after adjusting for illness severity, similar mortality.
In non-critical care patients, universal chlorhexidine bathing and mupirocin for MRSA carriers did not significantly reduce multidrug-resistant organisms.
Patient characteristics and modifiable system-based factors were associated with costly hospital readmission after sepsis.
Study validates accurate prediction rule for identifying febrile infants age <60 days at low risk for serious bacterial infections using urinalysis, absolute neutrophil count, and procalcitonin levels.
Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent.