Treatment with beta-blockers vs amiodarone, calcium channel blockers, or digoxin was associated with improved heart control at 1, but not 6 hours in patients with sepsis and atrial fibrillation.
Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.
The incidence of acute kidney injury in patients treated with vancomycin outpatient parenteral antimicrobial therapy was assessed, and risk factors for AKI in this population were identified.
Ertapenem and cefazolin combination therapy was studied to assess use as salvage therapy for persistent bacteremia against a MSSA blood-stream isolate.
Researchers conducted a retrospective cohort analysis to assess the prevalence and effects of inappropriate empirical antibiotic therapy for bloodstream infections.
There is a low incidence of second PJI in patients with bacteremia or hematogenous periprosthetic joint infection with concomitant prosthetic implants.
Investigators assessed patients who hospitalized with microbial S aureus bacteremia to determine the most meaningful cutoff point to define S aureus persistent bacteremia.
Treatment with daptomycin for bacteremia caused by methicillin-resistant Staphylococcus aureus complicated by septic pulmonary emboli was found to have a success rate comparable to daptomycin-ceftaroline fosamil.
IDSA has outlined several recommendations aimed at reducing the risk forunintended consequences of the Severe Sepsis and Septic Shock Early Management Bundle.
In patients with sepsis admitted to the ICU who were classified as obese experienced longer durations of ventilator use and had a higher risk for ARDS compared with patients with a normal BMI.
For many PICO questions, the literature review failed to identify sufficient data to develop strong recommendations for children with septic shock or other sepsis-associated organ dysfunction.
Among recipients of allogeneic hematopoietic cell transplantation (allo-HCT), gram-negative intestinal colonization is highly predictive of bloodstream infections.
