Sepsis

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Sepsis With Atrial Fibrillation: Effect of Phenylephrine vs Norepinephrine on Heart Rate

By

Pam Brick

In patients with sepsis and atrial fibrillation, how does treatment with phenylephrine vs norepinephrine affect heart rate?

Mortality Increased for Carbapenem-Resistant Infections Diagnosed via Blood Cultures

By

Estie Mermelstein, MSN, FNP-BC

Investigators assessed factors associated with 90- and 365-day mortality among veterans infected carbapenem-resistant Acinetobacter baumanii and carbapenem-resistant Pseudonomas aeruginosa.

Kidney Stress Biomarkers May Improve Severity Grading in Acute Kidney Injury

By

Natasha Persaud

Tissue inhibitor of metalloproteinases 2 (TIMP-2) and insulinlike growth factor binding protein 7 (IGFBP7) could be used for AKI staging.

Intrapartum Antibiotics Led to Increase in Resistant, Late-Onset Group B Streptococcal Disease

By

Jessica Nye, PhD

Researchers assessed the influence of intrapartum antibiotic prophylaxis on the emergence of antimicrobial resistant Group B streptococcal isolates.

COVID-19 Increases Mortality Risk in Patients Hospitalized With Sepsis

By

Estie Mermelstein, MSN, FNP-BC

Researchers compared clinical characteristics and outcomes among patients hospitalized with sepsis who were positive vs negative for COVID-19 infection.

Meropenem Treatment via Intermittent Bolus vs Extended Infusion in Critically ill Children

By

Jessica Nye, PhD

Researchers assessed clinical outcomes among critically ill children who received meropenem treatment via extended infusion vs intermittent bolus.

Sepsis Treatment: Effect of Vitamin C on Patient Outcomes

By

Melissa I. Alvarez

Should enteral or IV vitamin C become standard of care in the treatment of patients with sepsis?

Predictors of Mortality Identified in Patients With Suspected Bacterial Infections

By

Colby Stong

Researchers assessed independent predictors of all-cause mortality within a 2-year period among adult patients admitted to an emergency department with suspected bacterial infections.

Diagnostic Stewardship Reduces Blood Cultures, Antibiotic Use in PICU

In the pediatric intensive care unit, multidisciplinary diagnostic stewardship interventions can reduce blood culture and antibiotic use.

The Increase in Dementia Risk After Bacterial Pneumonia Differs by Causative Pathogen

By

Devon Cimino

Researchers assessed whether the increased risk for dementia observed among older adults diagnosed with bacterial pneumonia differs by causative pathogen.

Antibiotics Within the Same Class May Not Be Ideal in Combination Therapy for Bloodstream Infections

By

Jessica Nye, PhD

Researchers assessed the efficacy and interaction between the 4 most common antibiotic combinations for Escherichia coli bloodstream infections.

Antimicrobial Resistance, Mortality Risk Associated With Specific E coli Isolates in Patients With Bloodstream Infections

By

Shannon Storms

Researchers conducted a study that assessed antimicrobial resistance associated with specific Escherichia coli isolates in patients infected with E coli bacteremia.

Clinical Trial Revisits Vitamin C for Reducing Mortality From Septic Shock

By

Pam Brick

A recent clinical trial sought to confirm whether or not vitamin C monotherapy could reduce mortality in patients with septic shock.

Attributable vs Crude Mortality in Candida Bloodstream Infections

By

Jessica Nye, PhD

Researchers conducted a study that assessed the rate of 90-day all-cause crude mortality vs attributable mortality among patients with candida bloodstream infections.

Association Between Delayed Antibiotic Administration and Risk for Septic Shock

By

Estie Mermelstein, MSN, FNP-BC

Investigators conducted a study to determine whether early antibiotic administration decreases the risk for progression to septic shock among patients with suspected sepsis.

Does Chlorhexidine Cleansing Decrease the Risk for Neonatal Healthcare-Associated Infections?

By

Shannon Storms

Researchers conducted a meta-analysis to determine whether chlorhexidine cleansing effectively decreases the risk for healthcare-associated infections in neonates.

Risk for Early-Onset Sepsis Low for Infants With Low-Risk Delivery

Infants born at all gestational ages with low-risk delivery characteristics have a low risk for EOS and may not require initiation of empiric antibiotic therapy.

The Role of Lactate Dehydrogenase to Albumin Ratio in Patients With Lower Respiratory Tract Infection

By

Jessica Nye, PhD

Researchers conducted a study to determine whether the lactate dehydrogenase to albumin ratio is an independent prognostic factor predictive of in-hospital mortality in patients with lower respiratory tract infection.

Safety and Risks Associated With Midline vs Peripherally Inserted Central Catheters

By

Bradley van Paridon

Researchers conducted a study to compare outcomes among patients who underwent placement of either a midline or peripherally inserted central catheter due to either difficult vascular access or to receive antibiotic therapy.

Safety, Efficacy of Aminoglycosides or Polymyxin Monotherapy for Complicated UTI

By

Bradley van Paridon

Researchers conducted a study to assess the safety and efficacy of aminoglycosides or polymyxin monotherapy for the treatment of adults with complicated urinary tract infections caused by extensively drug-resistant Pseudomonas aeruginosa.