Investigators reported detailed microbiology, risk factors, and outcomes of secondary bloodstream infections in patients with severe COVID-19.
Investigators assessed whether a daily service of infectious disease consultation was more effective than weekly consultation to reduce antibiotic use without worsening clinical outcomes.
Study authors explored the clinical features and outcomes of mixed Candida albicans/bacterial bloodstream infections compared with monomicrobial Candida albicans bloodstream infections in adult patients.
Investigators studied the reactivation of cytomegalovirus in critically ill patients with sepsis and identified measured of CMV reactivation that were associated with worse clinical outcomes.
Study authors assessed the association of piperacillin/tazobactam MIC, meropenem MIC, and beta-lactam resistance genes with mortality in the MERINO trial.
Treatment with beta-blockers vs amiodarone, calcium channel blockers, or digoxin was associated with improved heart control at 1, but not 6 hours in patients with sepsis and atrial fibrillation.
Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.
The incidence of acute kidney injury in patients treated with vancomycin outpatient parenteral antimicrobial therapy was assessed, and risk factors for AKI in this population were identified.
The effect of ticagrelor in addition to cefazolin plus ertapenem for the clearance of S aureus bacteremia was assessed in a case study.
Ertapenem and cefazolin combination therapy was studied to assess use as salvage therapy for persistent bacteremia against a MSSA blood-stream isolate.
Researchers conducted a retrospective cohort analysis to assess the prevalence and effects of inappropriate empirical antibiotic therapy for bloodstream infections.
There is a low incidence of second PJI in patients with bacteremia or hematogenous periprosthetic joint infection with concomitant prosthetic implants.
The new doses of Vanco Ready include 150mL, 250mL, and 350mL premixed bags containing 750mg, 1.25g, and 1.75g of vancomycin, respectively.
Investigators assessed patients who hospitalized with microbial S aureus bacteremia to determine the most meaningful cutoff point to define S aureus persistent bacteremia.
Treatment with daptomycin for bacteremia caused by methicillin-resistant Staphylococcus aureus complicated by septic pulmonary emboli was found to have a success rate comparable to daptomycin-ceftaroline fosamil.
In a population-based study, risk for early-onset neonatal bacterial sepsis among newborns increased with maternal body mass index.
IDSA has outlined several recommendations aimed at reducing the risk forunintended consequences of the Severe Sepsis and Septic Shock Early Management Bundle.
A team of investigators conducted a 2-year prospective cohort study to assess the incidence of and outcomes associated with sepsis in newborns.
In patients with sepsis admitted to the ICU who were classified as obese experienced longer durations of ventilator use and had a higher risk for ARDS compared with patients with a normal BMI.
The Surviving Sepsis Campaign panel has issued recommendations to help support healthcare workers caring for critically ill patients with COVID-19.