Sepsis and septic shock are common oncologic emergencies that require vigilant, timely diagnosis and intervention. Timely and effective detection and treatment of these conditions are key to patient survival.
The researchers’ objective was to determine whether machine learning-derived estimated individual corticosteroid therapy effect yields better results than treat all or treat no one strategies in adult patients with septic shock.
Light sedation with dexmedetomidine does not lead to more days alive without acute brain dysfunction compared with propofol in mechanically ventilated adults with sepsis.
Danish researchers looked into whether hospital-diagnosed and community-treated infections are important risk factors for GBS by examining the magnitude and duration of associated GBS risk.
Study authors sought to determine whether hospital outcomes in childhood severe sepsis were influenced by race, ethnicity, or insurance status, which are proxies for socioeconomic positions.
For light sedation of mechanically ventilated adults with sepsis, outcomes do not differ significantly for those receiving dexmedetomidine or propofol.
Investigators assessed whether a daily service of infectious disease consultation was more effective than weekly consultation to reduce antibiotic use without worsening clinical outcomes.
Study authors explored the clinical features and outcomes of mixed Candida albicans/bacterial bloodstream infections compared with monomicrobial Candida albicans bloodstream infections in adult patients.
Investigators studied the reactivation of cytomegalovirus in critically ill patients with sepsis and identified measured of CMV reactivation that were associated with worse clinical outcomes.
Study authors assessed the association of piperacillin/tazobactam MIC, meropenem MIC, and beta-lactam resistance genes with mortality in the MERINO trial.
Treatment with beta-blockers vs amiodarone, calcium channel blockers, or digoxin was associated with improved heart control at 1, but not 6 hours in patients with sepsis and atrial fibrillation.
Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.
The incidence of acute kidney injury in patients treated with vancomycin outpatient parenteral antimicrobial therapy was assessed, and risk factors for AKI in this population were identified.
