Four Clinical Phenotypes Identified for Sepsis
Four distinct clinical phenotypes have been identified among patients with sepsis.
Sepsis
Sepsis
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Skin Cultures May Aid in Prediction of Bloodstream Infection Pathogens
Staphylococcus aureus and Pseudomonas aeruginosa skin cultures may help to predictthe pathogens involved in bloodstream infections.
Model Can Predict Sepsis Risk for Emergency Medical Admissions
Computer-aided National Early Warning Score model model accurately predicts sepsis for emergency medical admissions.
What Are the Effects of Culture-Negative vs Culture-Positive Sepsis?
People with culture-negative and culture-positive sepsis had similar characteristics and, after adjusting for illness severity, similar mortality.
Chlorhexidine Bathing Did Not Reduce Infections in Non-ICU Settings
In non-critical care patients, universal chlorhexidine bathing and mupirocin for MRSA carriers did not significantly reduce multidrug-resistant organisms.
Causes of Sepsis Readmission Often Linked to Infectious Etiologies
Patient characteristics and modifiable system-based factors were associated with costly hospital readmission after sepsis.
Prediction Rule for Serious Infection Accurate in Low-Risk Febrile Infants
Study validates accurate prediction rule for identifying febrile infants age <60 days at low risk for serious bacterial infections using urinalysis, absolute neutrophil count, and procalcitonin levels.
Machine-Learning Models Allow Early Detection of Sepsis in the NICU
Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent.
How Preventable Is Sepsis-Associated Death in Hospitalized Adults?
While sepsis was the most common immediate cause of death at 6 US academic and community hospitals, most patients had severe chronic comorbidities.
Hospital-Onset MRSA Decreased From 2002 to 2015
Staphylococcus aureus infections are still a concern in the United States, despite a decline seen in hospital-onset MRSA infections since 2005.
Readmission for Patients With Sepsis Common and Costly
Readmission after sepsis hospitalization is common and is associated with considerable costs.
Machine Learning Model for Early Sepsis Risk Stratification
A new sepsis screening tool developed using machine learning was timelier and more discriminating than several benchmark screening tools.
Experimental Test May Quickly Diagnose Sepsis
A blood test that can quickly diagnose dangerous sepsis infections has been developed.
Pneumococcal Sepsis Risk Remains High in Children After Vaccination
The incidence of pneumococcal sepsis in children remained substantial after the introduction of the pneumococcal conjugate vaccine in Switzerland.
No Association Between LDL Cholesterol Levels and Risk for Sepsis
A low level of LDL cholesterol was initially associated with increased risk for sepsis and admission to the ICU.
Practices Vary in Treating Adult Staphylococcus aureus Bacteremia
Practices vary among clinicians in diagnosing and managing Staphylococcus aureus bacteremia in adults.
Use of Single-Family Rooms Reduces Incidence of Neonatal Sepsis
Using a single-family room setting significantly reduced neonatal sepsis and improved breastfeeding rates at discharge.
Corticosteroid Use Reduces 28-Day Mortality in Sepsis
The administration of corticosteroids in patients with sepsis may be associated with significant improvement in patient outcomes.
Scenario-Based Survey of Empiric Antibiotic Treatment Thresholds
80 to 90% pathogen coverage was acceptable to physicians as a threshold for managing patients with mild and severe sepsis from bacterial infections.
Worse Outcomes in Community-Acquired Pneumonia Linked to Higher FGF21 Levels
Patients diagnosed with community-acquired pneumonia with higher levels of fibroblast growth factor-21 may have higher mortality rates and longer hospitalizations.
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