Persistent Inflammation After Sepsis Linked With Higher Mortality
About two-thirds of patients who survive hospitalization for sepsis have persistent elevation of inflammation and immunosuppression biomarker.
Sepsis
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High Prevalence of Infective Endocarditis in E faecalis Bacteremia
Data published in the Journal of the American College of Cardiology showed a high prevalence of definite infective endocarditis (IE) in patients with Enterococcus faecalis bacteremia (26%), suggesting that echocardiography should be considered in patients with E faecalis infection. A multicenter study using echocardiography was conducted from January 2014 to December 2016 in 344 consecutive…
Surviving Sepsis Campaign: 2018 Guidelines May Lead to Overdiagnosis, Overtreatment
The updated 1-hour sepsis care bundle is based on 2016 guidelines and recommends a specific set of treatments that should begin within 1 hour of sepsis recognition.
Safety Practice Violations Identified in Septic Arthritis Outbreak
Breaches of recommended infection prevention practices have been identified in an outbreak of septic arthritis cases after intra-articular injections performed in a private outpatient facility.
Predictors of Low-Risk Invasive Bacterial Infection in Febrile Infants
Infants have a low probability of invasive bacterial infection if they are ≤60 days old with a fever by history only and have a normal urinalysis result.
Accuracy of Rapid MALDI-TOF Bacterial Identification for Bloodstream Infections
The MALDI-TOF (Vitek MS, bioMérieux) assay demonstrated accuracy in the rapid identification of the most commonly isolated strains of Enterobacteriaceae, Staphylococcus aureus, and coagulase-negative staphylococci from colonies isolated from positive blood cultures, according to data presented at American Society of Microbiology (ASM) Microbe 2019, held June 20-24 in San Francisco, California. To test the accuracy…
Four Clinical Phenotypes Identified for Sepsis
Four distinct clinical phenotypes have been identified among patients with sepsis.
Skin Cultures May Aid in Prediction of Bloodstream Infection Pathogens
Staphylococcus aureus and Pseudomonas aeruginosa skin cultures may help to predictthe pathogens involved in bloodstream infections.
Model Can Predict Sepsis Risk for Emergency Medical Admissions
Computer-aided National Early Warning Score model model accurately predicts sepsis for emergency medical admissions.
What Are the Effects of Culture-Negative vs Culture-Positive Sepsis?
People with culture-negative and culture-positive sepsis had similar characteristics and, after adjusting for illness severity, similar mortality.
Chlorhexidine Bathing Did Not Reduce Infections in Non-ICU Settings
In non-critical care patients, universal chlorhexidine bathing and mupirocin for MRSA carriers did not significantly reduce multidrug-resistant organisms.
Causes of Sepsis Readmission Often Linked to Infectious Etiologies
Patient characteristics and modifiable system-based factors were associated with costly hospital readmission after sepsis.
Prediction Rule for Serious Infection Accurate in Low-Risk Febrile Infants
Study validates accurate prediction rule for identifying febrile infants age <60 days at low risk for serious bacterial infections using urinalysis, absolute neutrophil count, and procalcitonin levels.
Machine-Learning Models Allow Early Detection of Sepsis in the NICU
Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent.
How Preventable Is Sepsis-Associated Death in Hospitalized Adults?
While sepsis was the most common immediate cause of death at 6 US academic and community hospitals, most patients had severe chronic comorbidities.
Hospital-Onset MRSA Decreased From 2002 to 2015
Staphylococcus aureus infections are still a concern in the United States, despite a decline seen in hospital-onset MRSA infections since 2005.
Readmission for Patients With Sepsis Common and Costly
Readmission after sepsis hospitalization is common and is associated with considerable costs.
Machine Learning Model for Early Sepsis Risk Stratification
A new sepsis screening tool developed using machine learning was timelier and more discriminating than several benchmark screening tools.
Experimental Test May Quickly Diagnose Sepsis
A blood test that can quickly diagnose dangerous sepsis infections has been developed.
Pneumococcal Sepsis Risk Remains High in Children After Vaccination
The incidence of pneumococcal sepsis in children remained substantial after the introduction of the pneumococcal conjugate vaccine in Switzerland.
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