GBS infections in infants, cellulitis and necrotizing fasciitis, although uncommon in infants, requires swift treatment with antibiotics and occasionally surgical debridement.
Investigators sought to determine whether the use of ivermectin in patients with scabies leads to improved clinical and safety outcomes compared with permethrin.
Antibiotic prophylaxis did not significantly lower the risk of pelvic infection in low- and middle-income countries when administered before miscarriage surgery.
The Area, Systemic features, Swelling, Eye, Tenderness Score shows reliability, and applicability for use of IV antibiotics in a child with cellulitis.
Data limited the number of simple clinical characteristics that appear to identify skin and soft tissue infections that require high-level care in patient services
Mechanical bowel preparation with oral antibiotics may be the best approach to reduce surgical site infections in patients undergoing colorectal surgery.
Treatment with intravenous and oral delafloxacin, a fluoroquinolone antibiotic with gram-negative and gram-positive activity, was comparable to vancomycin/aztreonam in improving clinical signs and symptoms in acute bacterial and skin structure infections.
The approval was based on Phase 3 data from 2 studies in ABSSSI, where treatment with Nuzyra was compared with linezolid, and 1 study in CABP comparing Nuzyra with moxifloxacin. Across all 3 trials, Nuzyra was found to be effective and generally safe and well-tolerated.
A 9-point risk assessment (IVAT) identified persons with a history of injection drug use (IDU) safe for discharge and reduced the mean length of hospital stay (ALOS) by 20 days and total direct cost by 33%.
