Cases of Leishmaniasis Increasing in the United States, Vaccine in Development
Leishmaniasis is a neglected tropical disease that is transmitted by phlebotomine sand flies infected with Leishmania parasites.
Vector-Borne Illnesses
Vector-Borne Illnesses
Latest News
Possible Case of Locally Acquired Chagas Disease in Missouri
Findings in a case report in Morbidity and Mortality Weekly Report suggest the possibility that exposure to Trypanosoma cruzi occurred locally in Missouri.
High Number of US Cases of Travel-Linked Dengue Virus From 2010 to 2017
During 2010 to 2017, there were 5,009 travel-associated and 378 locally acquired confirmed or probable dengue virus cases in the United States.
Intradermal Rabies Vaccine Noninferior to Intramuscular Vaccine
Intradermal administration of the rabies vaccine may produce similar antibody titers at a fraction of the intramuscular administration dose.
Genetically Modified Mosquitos Neutralize Dengue Virus
Researchers at the University of California San Diego have identified a target gene in mosquitos that renders the insects completely refractory to all 4 serotypes of the dengue virus and thus, incapable of transmitting the virus to humans, according to study results published in PLoS Pathogens.1 Dengue fever is caused by infection with 1 of…
Antimalarial Drugs May Reduce Polyautoimmunity in Systemic Lupus Erythematosus
Researchers evaluated the frequency of polyautoimmunity and its associated factors in a large retrospective cohort of patients with systemic lupus erythematosus.
Accelerated Dengue/Yellow Fever Vaccine Schedule Noninferior to Conventional Schedule
Study data demonstrates an early benefit to receiving Japanese Encephalitis vaccination prior to CYD-TDV in terms of higher overall anti-dengue virus neutralizing titers, although this benefit appears to wane after several months.
Safety and Effectiveness of Apheresis in Treatment of Several Vector-Borne Illnesses
Apheresis may be a useful adjunct treatment for patients with babesiosis, or loiasis.
Tafenoquine Now Available for Malaria Prevention
Arakoda (tafenoquine; 60 Degrees Pharmaceuticals) has been made available in the US for the prevention of malaria in patients aged ≥18 years.
Diagnosing Tick-Borne Encephalitis With Immunoassays
Diagnosing tick-borne encephalitis with commercial enzyme-linked immunosorbent assay may lack specificity and need confirmatory testing.
Review Indicates Inclusion of Psychiatric Illness Association in Proposed Lyme Disease Guidelines
Researchers reviewed the recently released Lyme disease guidelines and addressed their appropriate inclusion of and association with psychiatric illnesses.
Short-Course, High-Dose Primaquine Effective for Radical Cure of P vivax Malaria
For patients with normal glucose-6-phosphate dehydrogenase activity in malaria-endemic areas where frequent relapsing strains of Plasmodium vivax are prevalent, a 7-day high-dose course of primaquine was noninferior to a 14-day course.
Connecticut Sees First Death This Year From Mosquito-Borne EEE
A Connecticut resident has died from eastern equine encephalitis (EEE), the first such death in the state since 2013.
Two More Cases of EEE Virus Confirmed in Massachusetts
Two new human cases of mosquito-borne Eastern equine encephalitis were confirmed by the Massachusetts Department of Public Health.
Massachusetts Communities at ‘Critical Risk’ for Mosquito-Borne Virus
Dozens of communities at high or moderate risk for Eastern equine encephalitis
Suboptimal Prospects for Severe Malaria Treatment in the United States
Eli Lilly was the only pharmaceutical company providing quinidine gluconate in the United States, but in November 2017 it stopped manufacturing the drug and the remaining supplies expired.
Seven Day Primaquine Treatment Is Safe, Noninferior to 14 Day Course
In patients with malaria who have normal levels of glucose-6-phosphate dehydrogenase, 7-day primaquine was well tolerated and noninferior to 14-day primaquine.
In 2018, 2,813 Cases of Domestic Arbovirus Reported in the United States
A total of 2,813 cases of domestic arboviral disease were identified in 2018, of which 94% were West Nile Virus.
Antimalarial Drug Combination No Longer Effective Against Evolving P falciparum Malaria
Dihydroartemisinin plus piperaquine for treating multidrug-resistant Plasmodium falciparum malaria should no longer be used in southeast Asia as a result of new resistance mutations.
FDA Clears New Testing Algorithm for Lyme Disease Diagnosis
The FDA has cleared for marketing the ZEUS Borrelia Modified Two-Tiered Testing algorithm to help in the diagnosis of Lyme disease.
Should Community Pharmacies Have Prescribing Power for the Treatment of Lyme Disease?
Lyme disease, a vector-borne illness caused by the bacteria Borrelia burgdorferi, is transmitted to humans by deer ticks. It is currently nearing endemic levels of infection in North America; the United States Centers for Disease Control and Prevention (CDC) has reported a 130.6% increase in confirmed cases between 1997 and 2017 (12,801-29,513 cases, respectively)1. Other…
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