Vectors With a Vengeance: How Venezuela’s Political Crisis Opens Doors to Disease
Venezuela has endured a decade of political, economic, and social unrest, which has contributed to regional epidemics of vector-borne illnesses.
Vector-Borne Illnesses
Vector-Borne Illnesses
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CDC: Wildlife Rabies, Especially in Bats, Poses Risk in US
Seventy percent of rabies infections acquired in the United States attributed to bats
Antiparasitic Ivermectin Has High Mosquitocidal Efficacy
A 3-day course of either 300 mcg/kg/day or 600 mcg/kg/day of ivermectin may have similar mosquitocidal effects for up to 28-days postfeeding via membrane or direct skin feeding.
First Vaccine Approved to Protect Against Dengue in Endemic Areas of the US
The Food and Drug Administration (FDA) has approved Dengvaxia (dengue tetravalent vaccine, live; Sanofi) for the prevention of dengue disease caused by dengue virus serotypes 1, 2, 3 and 4.
Malaria Incidence Higher Among African Travelers Returning to France
Significant changes may have occurred in France, in the population that developed malaria after travel in endemic areas, which implies that preventative strategies need to be adapted.
CDC: First Confirmed ID of ‘Kissing Bug’ in Delaware
The first confirmed identification of the bloodsucking “kissing bug” in Delaware involves one that bit a girl on the face last summer.
Treatment for Severe Malaria Receives Breakthrough Therapy Status
The Food and Drug Administration has granted an investigational treatment for severe malaria Breakthrough Therapy designation.
Malawi First Country to Immunize Children Against Malaria
The vaccine, called Mosquirix, was approved by the European Medicines Agency in 2015
Frequent, Repeated Mass Ivermectin Administration Reduces Malaria Transmission
Frequently repeated mass administration of ivermectin during transmission season may reduce the incidence of uncomplicated malaria episodes in children living in endemic regions, according to study results published in the Lancet.1 Since 2017, when researchers at the World Health Organization suggested that the global fight against malaria had stalled,2 novel ways to prevent the transmission…
Reported Cases of Spotted Fever Rickettsiosis Rarely Confirmed
Only 1.0 percent of reported cases of spotted fever rickettsioses (SFR) meet the confirmed case definition.
Guidance Lists New First-Line Treatment for Severe Malaria in the US
The drug artesunate will become the first-line treatment for severe malaira in the US.
No Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention
The addition of azithromycin to seasonal malaria chemoprevention may reduce mortality and morbidity in African children.
Experts Support Malaria Vaccine Trials in Pregnant Women
An expert meeting convened at NIAID, NIH, in Rockville, Maryland, in 2016 to discuss the rationale and design of malaria vaccine trials in pregnant women.
Single-Dose Tafenoquine Effective in Preventing Relapse of P vivax Malaria
Compared with placebo, single-dose tafenoquine significantly lowered risk for Plasmodium vivax malaria relapse at 6 months.
Novel Vaccine for Pregnancy-Associated Malaria Is Well Tolerated
A novel malaria vaccine candidate is well tolerated and induced functionally active antibodies.
Dengue Vaccine Candidate TAK-003 Looks Promising in Phase 3 Trial
The TIDES trial is investigating the safety and efficacy of 2 doses of TAK-003 in preventing dengue fever caused by any of the 4 dengue virus serotypes.
Screening Blood Donations Mitigates Transfusion-Transmitted Babesiosis Risk
Screening blood donations for Babesia microti in endemic areas eliminates transfusion-transmitted babesiosis effectively.
Safety of Escalating Doses of Tribendimidine in Children With Hookworm
Tribendimidine 400 mg has demonstrated efficacy and tolerability in children with mild hookworm infections.
Tafenoquine Appears Safe and Effective for Prevention of Malaria
Chemoprophylaxis with tafenoquine is safe and effective for preventing malaria in healthy non-immune individuals challenged with blood stage P falciparum.
Prenatal Malaria Exposure Modulates Innate Immune Responses at Birth
Placental malaria has a profound effect on the fetal immune system, and prenatal malaria exposure categories may drive heterogeneity to malaria susceptibility.
A Single Triple-Drug Treatment for Lymphatic Filariasis
A single triple-drug treatment for lymphatic filariasis may prove to be more effective and potent than a double-drug regimen.
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