Vectors With a Vengeance: How Venezuela’s Political Crisis Opens Doors to Disease
Venezuela has endured a decade of political, economic, and social unrest, which has contributed to regional epidemics of vector-borne illnesses.
Vector-Borne Illnesses
Vector-Borne Illnesses
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Frequent, Repeated Mass Ivermectin Administration Reduces Malaria Transmission
Frequently repeated mass administration of ivermectin during transmission season may reduce the incidence of uncomplicated malaria episodes in children living in endemic regions, according to study results published in the Lancet.1 Since 2017, when researchers at the World Health Organization suggested that the global fight against malaria had stalled,2 novel ways to prevent the transmission…
Reported Cases of Spotted Fever Rickettsiosis Rarely Confirmed
Only 1.0 percent of reported cases of spotted fever rickettsioses (SFR) meet the confirmed case definition.
Guidance Lists New First-Line Treatment for Severe Malaria in the US
The drug artesunate will become the first-line treatment for severe malaira in the US.
No Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention
The addition of azithromycin to seasonal malaria chemoprevention may reduce mortality and morbidity in African children.
Experts Support Malaria Vaccine Trials in Pregnant Women
An expert meeting convened at NIAID, NIH, in Rockville, Maryland, in 2016 to discuss the rationale and design of malaria vaccine trials in pregnant women.
Single-Dose Tafenoquine Effective in Preventing Relapse of P vivax Malaria
Compared with placebo, single-dose tafenoquine significantly lowered risk for Plasmodium vivax malaria relapse at 6 months.
Novel Vaccine for Pregnancy-Associated Malaria Is Well Tolerated
A novel malaria vaccine candidate is well tolerated and induced functionally active antibodies.
Dengue Vaccine Candidate TAK-003 Looks Promising in Phase 3 Trial
The TIDES trial is investigating the safety and efficacy of 2 doses of TAK-003 in preventing dengue fever caused by any of the 4 dengue virus serotypes.
Screening Blood Donations Mitigates Transfusion-Transmitted Babesiosis Risk
Screening blood donations for Babesia microti in endemic areas eliminates transfusion-transmitted babesiosis effectively.
Safety of Escalating Doses of Tribendimidine in Children With Hookworm
Tribendimidine 400 mg has demonstrated efficacy and tolerability in children with mild hookworm infections.
Tafenoquine Appears Safe and Effective for Prevention of Malaria
Chemoprophylaxis with tafenoquine is safe and effective for preventing malaria in healthy non-immune individuals challenged with blood stage P falciparum.
Prenatal Malaria Exposure Modulates Innate Immune Responses at Birth
Placental malaria has a profound effect on the fetal immune system, and prenatal malaria exposure categories may drive heterogeneity to malaria susceptibility.
A Single Triple-Drug Treatment for Lymphatic Filariasis
A single triple-drug treatment for lymphatic filariasis may prove to be more effective and potent than a double-drug regimen.
Early Benznidazole Treatment Improves Outcomes in Chagas Disease
Benznidazole treatment during the early phases of chronic Chagas disease infection reduced parasitemia significantly.
Climate Change Expected to Lead to Rise in Lyme Disease
Rising temperatures contribute to more ticks and greater availability of hosts
Certain Iron Deficiencies May Protect Against Malaria in African Children
Iron deficiency may protect African children against malaria infection when defined using ferritin and transferrin saturation.
CDC: First Case of Rat-Borne Andes Virus Diagnosed in the US
The first confirmed U.S. case of a virus carried by South American rodents occurred earlier this year.
Flea-Borne Typhus Outbreak in Los Angeles County
An outbreak of flea-borne typhus in Los Angeles County has so far resulted in 57 cases, including 20 in Pasadena and nine in downtown Los Angeles.
CYP2D6 Enzymatic Activity May Increase Primaquine Malaria Treatment Efficacy
A natural variability of genotype-determined, CYP2D6-dependent metabolism of primaquine phosphate is associated with an increased risk of failure in the treatment of P vivax malaria.
Short Course Primaquine Regimens for P vivax Malaria Improves Treatment Efficacy
Chloroquine with either 7- or 14-day primaquine regimens provided highly effective radical cure of vivax malaria on the Thailand-Myanmar border.
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