Influenza

High-Dose Influenza Vaccination May Benefit Transplant Recipients

High-Dose Influenza Vaccination May Benefit Transplant Recipients

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Double-dose influenza vaccine is safe and may increase antibody response in solid-organ transplant recipients

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Statins Increase Risk for Medically Attended Acute Respiratory Illness

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Elderly patients who have been inoculated with the influenza vaccine and who also use a statin are at a greater risk for medically attended acute respiratory illness.

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

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Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.

Three-Quarters of Health Care Workers Got Flu Shot Last Year

Three-Quarters of Health Care Workers Got Flu Shot Last Year

Just over three-quarters of health care personnel received a flu vaccine last season.

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

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NasoVAX, an adenovirus-based intranasal flu vaccine, shows tolerability, safety, and higher cellular immune response compared to an injectable vaccine.

Baloxavir Marboxil Safe and Effective for High-Risk Influenza Patients

Baloxavir Marboxil Safe and Effective for High-Risk Influenza Patients

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When compared to placebo, baloxavir marboxil was associated with reduced risk of influenza complications and faster recovery.

80,000 Americans Died From Influenza Over Last Year

80,000 Americans Died From Influenza Over Last Year

2017 to 2018 flu strains affect the very young and elderly especially signifantly; poor vaccine/strain match-up

Is Mandatory Genetic Testing for Influenza Infection Variants Ethical?

Is Mandatory Genetic Testing for Influenza Infection Variants Ethical?

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Mandatory genetic testing may also constitute an undue threat to employee autonomy and privacy.

Active Choice Intervention Tied to Increase in Flu Shot Rates

Active Choice Intervention Tied to Increase in Flu Shot Rates

An active choice intervention is associated with an increase in influenza vaccination rates.

Baloxavir Marboxil, Safe and Effective in Treatment of Uncomplicated Influenza

Baloxavir Marboxil, Safe and Effective in Treatment of Uncomplicated Influenza

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A single dose of baloxavir marboxil was superior to placebo in controlling influenza symptoms in patients with uncomplicated disease.

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

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Influenza proved to be an independent risk factor for invasive pulmonary aspergillosis.

AAP Updates Recommendations for Pediatric Flu Vaccination

AAP Updates Recommendations for Pediatric Flu Vaccination

All children and adolescents are advised to undergo annual influenza immunization, ideally with an inactivated influenza vaccine.

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

The mysterious illness that kept a plane away from the terminal after some passengers reported feeling sick has been confirmed as the flu.

AAP Issues Updated Influenza Vaccine Recommendations

AAP Issues Updated Influenza Vaccine Recommendations

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According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

Immune Cells' Gene Expression May Predict Flu Susceptibility

Immune Cells' Gene Expression May Predict Flu Susceptibility

KLRD1-expressing natural killer cells may be a biomarker for influenza susceptibility.

China Withholding H7N9 Bird Flu Virus Samples From the United States

China Withholding H7N9 Bird Flu Virus Samples From the United States

Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.

Obesity May Increase Duration of Influenza A Virus Shedding in Adults

Obesity May Increase Duration of Influenza A Virus Shedding in Adults

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Obesity may play an important role in influenza transmission, highlighting the importance of working toward controlling and preventing the obesity epidemic.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

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In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

Patients with rheumatoid arthritis, particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality.

Comparison of Live Attenuated vs Inactive Influenza Vaccine in Nursing Mothers

Comparison of Live Attenuated vs Inactive Influenza Vaccine in Nursing Mothers

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Both LAIV and IIV are safe for nursing mothers, however, breast milk and serum antibody responses were higher for IIV.

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

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Immune priming with seasonal H1N1 viruses earlier in life and egg-adaptation in vaccines can impact antibody responses following influenza vaccination.

Predictors of Influenza Vaccine Acceptance in Inflammatory Rheumatic Diseases

Predictors of Influenza Vaccine Acceptance in Inflammatory Rheumatic Diseases

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A direct recommendation from physicians had the greatest effect on patients' positive vaccination status.

Mucus Protects Airborne Flu Virus at All Humidities

Mucus Protects Airborne Flu Virus at All Humidities

Influenza virus aerosols remain infectious at all humidity levels.

Influenza-MRSA Co-Infection May Require Vancomycin Plus Second Antibiotic

Influenza-MRSA Co-Infection May Require Vancomycin Plus Second Antibiotic

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The early addition of a second anti-MRSA antibiotic to vancomycin may reduce mortality in severe cases of influenza-MRSA co-infection in children.

Priority Review Granted to Novel Oral Influenza Treatment

Priority Review Granted to Novel Oral Influenza Treatment

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Baloxavir marboxil, an investigational, oral treatment for acute uncomplicated influenza in those aged ≥12 years has been granted Priority Review by the FDA.

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

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The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.

Mandatory Influenza Vaccination Advised for Healthcare Personnel in VA, Non-VA Hospitals

Mandatory Influenza Vaccination Advised for Healthcare Personnel in VA, Non-VA Hospitals

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A national survey was conducted to assess influenza prevention practices in Veterans Affairs and non-Veterans Affairs hospitals in the United States.

Increase in Requirement for Influenza Vaccinations at Non-VA Hospitals

Increase in Requirement for Influenza Vaccinations at Non-VA Hospitals

At non VA hospitals, but not in VA hospitals, there was an increase in mandatory influenza vaccination requirements for health care personnel from 2013 to 2017.

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

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The advisory comes early as physicians are currently placing vaccine orders.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

Even relatively low-efficacy influenza vaccines can have a high impact, especially with optimal distribution across age groups.

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