Nosocomial Infections

Feature Article

Identifying the Source of C difficile in Hospitalized Patients

Identifying the Source of C difficile in Hospitalized Patients

Clostridium difficile is the most common cause of healthcare-associated infections, with as many as 500,000 cases occurring annually in the United States. Efforts to prevent transmission within hospitals typically focus on patients with symptomatic Clostridium difficile infection.

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Emotional Pain Tied to Health Care-Associated Infections

Emotional Pain Tied to Health Care-Associated Infections

Many patients with health care-associated infections concerned about transmission.

Decline in Hospital-Acquired Conditions Continues

Decline in Hospital-Acquired Conditions Continues

Drop in adverse drug events, injuries from falls prevented 8,000 deaths, saved 2.9 billion.

Time to Blood Culture Positivity Predictive of Mortality in  S Aureus  Infective Endocarditis

Time to Blood Culture Positivity Predictive of Mortality in S Aureus Infective Endocarditis

Time to blood culture positivity (TTP) provided reliable information on the risk for infective endocarditis (IE) in patients with Staphylococcus aureus bacteraemia.

Genome Sequencing Traces K pneumoniae Outbreak to Outpatient Clinic

Genome Sequencing Traces K pneumoniae Outbreak to Outpatient Clinic

An investigation into an outbreak of NDM-producing Klebsiella pneumoniae across 2 Belgian hospitals identified an outpatient clinic as the likely common site of transfer and highlights the importance of infection control measures in outpatient settings.

Antimicrobial Lock Solutions Are Cost-Effective for Preventing Central Line-Associated Bloodstream Infections

Antimicrobial Lock Solutions Are Cost-Effective for Preventing Central Line-Associated Bloodstream Infections

Antimicrobial lock solutions are an effective clinical and cost-effective strategy for preventing central line-associated bloodstream infections.

Are Hospital Staff Failing to Practice Transmission-Based Precautions?

Are Hospital Staff Failing to Practice Transmission-Based Precautions?

Active failures in personal protective equipment use by healthcare personnel may potentially lead to self-contamination.

Post-Endoscopic Infection More Common Than Previously Thought

Post-Endoscopic Infection More Common Than Previously Thought

The rates of post-endoscopic infection within seven days vary from 1.1 per 1,000 procedures for screening colonoscopy to 3 per 1,000 procedures for osophagogastroduodenoscopies.

Sepsis-3 Septic Shock Criteria vs SIRS to Predict Mortality in Hospitalized Patients

Sepsis-3 Septic Shock Criteria vs SIRS to Predict Mortality in Hospitalized Patients

Although the Systemic Inflammatory Response Syndrome criteria have been used for decades to identify sepsis in patients with suspected infection, they have been re-evaluated in the Third International Consensus Definitions for Sepsis and Septic Shock.

No Clear Exposure-Response Relationship Found for Micafungin in Neonatal Candidiasis

No Clear Exposure-Response Relationship Found for Micafungin in Neonatal Candidiasis

No clear relationship was found between the average daily area under concentration-time curve and mycologic response for micafungin in neonates.

MRSA- and MSSA-Related Hospitalization Costs Assessed

MRSA- and MSSA-Related Hospitalization Costs Assessed

Increasing costs associated with hospitalizations involving MSSA infection are expected to surpass national costs for hospitalizations associated with MRSA.

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