Nosocomial Infections

Management of <i>Mycobacterium chimaera</i> Outbreak From Heater-Cooler Units

Management of Mycobacterium chimaera Outbreak From Heater-Cooler Units

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There is currently a global outbreak of disseminated Mycobacterium chimaera related to the widely used surgical device LivaNova 3T heater-cooler unit contamination.

Many Linens Delivered To US Hospitals Contaminated With Mucorales Mold

Many Linens Delivered To US Hospitals Contaminated With Mucorales Mold

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A recent microbiological surveillance study found that >10% of linens tested positive for the fungi Mucorales at 20% of the hospitals included in the study.

Emotional Pain Tied to Health Care-Associated Infections

Emotional Pain Tied to Health Care-Associated Infections

Many patients with health care-associated infections concerned about transmission.

Individualized Treatment of Late Acute Prosthetic Joint Infection May Decrease Failure Rate

Individualized Treatment of Late Acute Prosthetic Joint Infection May Decrease Failure Rate

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Treatment strategies for late acute prosthetic joint infections should be individualized according to patients' age, comorbidities, clinical presentation, and microorganism causing the infection.

Decline in Hospital-Acquired Conditions Continues

Decline in Hospital-Acquired Conditions Continues

Drop in adverse drug events, injuries from falls prevented 8,000 deaths, saved 2.9 billion.

Candidemia and <i>Clostridium difficile</i> Coinfection Common in Certain High-Risk Groups

Candidemia and Clostridium difficile Coinfection Common in Certain High-Risk Groups

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Candidemia and Clostridium difficile infection (CDI) are both common healthcare-associated infections with overlapping risk factors, and almost 1 in 10 patients with candidemia are coinfected with CDI.

Time to Blood Culture Positivity Predictive of Mortality in <i> S Aureus </i> Infective Endocarditis

Time to Blood Culture Positivity Predictive of Mortality in S Aureus Infective Endocarditis

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Time to blood culture positivity (TTP) provided reliable information on the risk for infective endocarditis (IE) in patients with Staphylococcus aureus bacteraemia.

Genome Sequencing Traces <i>K pneumoniae</i> Outbreak to Outpatient Clinic

Genome Sequencing Traces K pneumoniae Outbreak to Outpatient Clinic

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An investigation into an outbreak of NDM-producing Klebsiella pneumoniae across 2 Belgian hospitals identified an outpatient clinic as the likely common site of transfer and highlights the importance of infection control measures in outpatient settings.

Identifying the Source of <i>C difficile</i> in Hospitalized Patients

Identifying the Source of C difficile in Hospitalized Patients

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Clostridium difficile is the most common cause of healthcare-associated infections, with as many as 500,000 cases occurring annually in the United States. Efforts to prevent transmission within hospitals typically focus on patients with symptomatic Clostridium difficile infection.

Antimicrobial Lock Solutions Are Cost-Effective for Preventing Central Line-Associated Bloodstream Infections

Antimicrobial Lock Solutions Are Cost-Effective for Preventing Central Line-Associated Bloodstream Infections

Antimicrobial lock solutions are an effective clinical and cost-effective strategy for preventing central line-associated bloodstream infections.

Are Hospital Staff Failing to Practice Transmission-Based Precautions?

Are Hospital Staff Failing to Practice Transmission-Based Precautions?

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Active failures in personal protective equipment use by healthcare personnel may potentially lead to self-contamination.

Post-Endoscopic Infection More Common Than Previously Thought

Post-Endoscopic Infection More Common Than Previously Thought

The rates of post-endoscopic infection within seven days vary from 1.1 per 1,000 procedures for screening colonoscopy to 3 per 1,000 procedures for osophagogastroduodenoscopies.

Sepsis-3 Septic Shock Criteria vs SIRS to Predict Mortality in Hospitalized Patients

Sepsis-3 Septic Shock Criteria vs SIRS to Predict Mortality in Hospitalized Patients

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Although the Systemic Inflammatory Response Syndrome criteria have been used for decades to identify sepsis in patients with suspected infection, they have been re-evaluated in the Third International Consensus Definitions for Sepsis and Septic Shock.

No Clear Exposure-Response Relationship Found for Micafungin in Neonatal Candidiasis

No Clear Exposure-Response Relationship Found for Micafungin in Neonatal Candidiasis

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No clear relationship was found between the average daily area under concentration-time curve and mycologic response for micafungin in neonates.

MRSA- and MSSA-Related Hospitalization Costs Assessed

MRSA- and MSSA-Related Hospitalization Costs Assessed

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Increasing costs associated with hospitalizations involving MSSA infection are expected to surpass national costs for hospitalizations associated with MRSA.

Severe Liver Failure Is Strongest Independent Risk Factor for Mortality in Infectious Endocarditis

Severe Liver Failure Is Strongest Independent Risk Factor for Mortality in Infectious Endocarditis

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Severe liver failure is the strongest predictive factor of mortality related to infectious endocarditis in patients with liver cirrhosis.

Environmental Screening Effective Proxy for Evaluating MRSA and VRE Rate in Nursing Facilities

Environmental Screening Effective Proxy for Evaluating MRSA and VRE Rate in Nursing Facilities

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Researchers assessed the ability of environmental screening as a proxy for patient colonization to reduce transmission of MRSA and VRE in nursing facilities.

<i>Burkholderia cepacia</i> Outbreak Tied to No-Rinse Cleansing Foam

Burkholderia cepacia Outbreak Tied to No-Rinse Cleansing Foam

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As a result of the tests, the FDA is advising consumers and clinicians to avoid using all lots of Remedy Essentials No-Rinse Cleansing Foam.

Military Personnel Remain at Risk for Infection Long After Hospital Discharge

Military Personnel Remain at Risk for Infection Long After Hospital Discharge

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Deployment-related trauma infectious complications continue after initial hospital discharge and into Veterans Affairs healthcare.

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

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Findings do not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods, with third-generation or fourth-generation cephalosporins, piperacillin-tazobactam, and carbapenems reduces the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Drug-Related Endocarditis Cases Up From 2007 to 2015

Drug-Related Endocarditis Cases Up From 2007 to 2015

Over the last 9 years, there was an increase in the number of endocarditis cases, which mirrored the increase in concomitant use of mixed drugs.

Curbing Overuse of Blood Cultures in the Emergency Department

Curbing Overuse of Blood Cultures in the Emergency Department

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Training on adherence to guidelines, the development of guidelines specific to the pediatric population, and the employment of tools and techniques to decrease contamination of blood cultures could decrease the overuse of blood cultures.

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists are increasingly becoming involved in antibiotic surveillance, including e-surveillance methods; formulation of antibiotic-use policies; and day-to-day control of problematic antibiotic use.

<i>Clostridium difficile</i> Infection in the Intensive Care Setting

Clostridium difficile Infection in the Intensive Care Setting

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It is important to understand the relative severity of CDI in patients in the ICU because it effects treatment decisions. However, primary prevention remains a vitally important strategy to limit morbidity and mortality related to CDI in this vulnerable patient population.

Reducing Mortality in Patients With Right-Sided Infective Endocarditis

Reducing Mortality in Patients With Right-Sided Infective Endocarditis

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Optimal management for severely ill patients with right-sided infective endocarditis (RSIE) remains challenging. The goal of this study was to determine outcome and associated prognostic factors in a population of ICU patients with RSIE.

Incidence of Surgical Site Infections Highest in Lower-Income Countries

Incidence of Surgical Site Infections Highest in Lower-Income Countries

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A large proportion of surgical site infections are caused by organisms resistant to prophylactic antibiotics, with the greatest apparent burden in low- and middle-income countries

Vegetation Size May Increase Mortality Risk in Infective Endocarditis

Vegetation Size May Increase Mortality Risk in Infective Endocarditis

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In this systematic review and meta-analysis, patients with infective endocarditis with vegetations greater than 10mm in size had significantly increased risk of systemic embolism and mortality.

FDA: Avycaz Approved for Hospital-Acquired, Ventilator-Associated Pneumonia

FDA: Avycaz Approved for Hospital-Acquired, Ventilator-Associated Pneumonia

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The FDA has approved the use of Avycaz (ceftazidime, avibactam) to treat hospital-acquired bacterial pneumonia.

Prophylactic Antibiotic Does Not Reduce SSI Risk After Orthopedic Implant Removal

Prophylactic Antibiotic Does Not Reduce SSI Risk After Orthopedic Implant Removal

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Although removal of orthopedic implants is considered to be associated with low risk of infection, higher rates of surgical site infection following these procedures have been reported.

Ceftazidime-Avibactam Efficacious in Nosocomial Pneumonia

Ceftazidime-Avibactam Efficacious in Nosocomial Pneumonia

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Results support a role for ceftazidime-avibactam as a potential alternative to carbapenems in patients with nosocomial pneumonia (including ventilator-associated pneumonia) caused by Gram-negative pathogens.

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