Nosocomial Infections

Sepsis-3 Septic Shock Criteria vs SIRS to Predict Mortality in Hospitalized Patients

Sepsis-3 Septic Shock Criteria vs SIRS to Predict Mortality in Hospitalized Patients

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Although the Systemic Inflammatory Response Syndrome criteria have been used for decades to identify sepsis in patients with suspected infection, they have been re-evaluated in the Third International Consensus Definitions for Sepsis and Septic Shock.

No Clear Exposure-Response Relationship Found for Micafungin in Neonatal Candidiasis

No Clear Exposure-Response Relationship Found for Micafungin in Neonatal Candidiasis

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No clear relationship was found between the average daily area under concentration-time curve and mycologic response for micafungin in neonates.

MRSA- and MSSA-Related Hospitalization Costs Assessed

MRSA- and MSSA-Related Hospitalization Costs Assessed

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Increasing costs associated with hospitalizations involving MSSA infection are expected to surpass national costs for hospitalizations associated with MRSA.

Severe Liver Failure Is Strongest Independent Risk Factor for Mortality in Infectious Endocarditis

Severe Liver Failure Is Strongest Independent Risk Factor for Mortality in Infectious Endocarditis

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Severe liver failure is the strongest predictive factor of mortality related to infectious endocarditis in patients with liver cirrhosis.

Environmental Screening Effective Proxy for Evaluating MRSA and VRE Rate in Nursing Facilities

Environmental Screening Effective Proxy for Evaluating MRSA and VRE Rate in Nursing Facilities

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Researchers assessed the ability of environmental screening as a proxy for patient colonization to reduce transmission of MRSA and VRE in nursing facilities.

<i>Burkholderia cepacia</i> Outbreak Tied to No-Rinse Cleansing Foam

Burkholderia cepacia Outbreak Tied to No-Rinse Cleansing Foam

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As a result of the tests, the FDA is advising consumers and clinicians to avoid using all lots of Remedy Essentials No-Rinse Cleansing Foam.

Military Personnel Remain at Risk for Infection Long After Hospital Discharge

Military Personnel Remain at Risk for Infection Long After Hospital Discharge

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Deployment-related trauma infectious complications continue after initial hospital discharge and into Veterans Affairs healthcare.

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

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Findings do not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods, with third-generation or fourth-generation cephalosporins, piperacillin-tazobactam, and carbapenems reduces the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Drug-Related Endocarditis Cases Up From 2007 to 2015

Drug-Related Endocarditis Cases Up From 2007 to 2015

Over the last 9 years, there was an increase in the number of endocarditis cases, which mirrored the increase in concomitant use of mixed drugs.

Curbing Overuse of Blood Cultures in the Emergency Department

Curbing Overuse of Blood Cultures in the Emergency Department

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Training on adherence to guidelines, the development of guidelines specific to the pediatric population, and the employment of tools and techniques to decrease contamination of blood cultures could decrease the overuse of blood cultures.

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists are increasingly becoming involved in antibiotic surveillance, including e-surveillance methods; formulation of antibiotic-use policies; and day-to-day control of problematic antibiotic use.

Reducing Mortality in Patients With Right-Sided Infective Endocarditis

Reducing Mortality in Patients With Right-Sided Infective Endocarditis

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Optimal management for severely ill patients with right-sided infective endocarditis (RSIE) remains challenging. The goal of this study was to determine outcome and associated prognostic factors in a population of ICU patients with RSIE.

Incidence of Surgical Site Infections Highest in Lower-Income Countries

Incidence of Surgical Site Infections Highest in Lower-Income Countries

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A large proportion of surgical site infections are caused by organisms resistant to prophylactic antibiotics, with the greatest apparent burden in low- and middle-income countries

Vegetation Size May Increase Mortality Risk in Infective Endocarditis

Vegetation Size May Increase Mortality Risk in Infective Endocarditis

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In this systematic review and meta-analysis, patients with infective endocarditis with vegetations greater than 10mm in size had significantly increased risk of systemic embolism and mortality.

FDA: Avycaz Approved for Hospital-Acquired, Ventilator-Associated Pneumonia

FDA: Avycaz Approved for Hospital-Acquired, Ventilator-Associated Pneumonia

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The FDA has approved the use of Avycaz (ceftazidime, avibactam) to treat hospital-acquired bacterial pneumonia.

Prophylactic Antibiotic Does Not Reduce SSI Risk After Orthopedic Implant Removal

Prophylactic Antibiotic Does Not Reduce SSI Risk After Orthopedic Implant Removal

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Although removal of orthopedic implants is considered to be associated with low risk of infection, higher rates of surgical site infection following these procedures have been reported.

Ceftazidime-Avibactam Efficacious in Nosocomial Pneumonia

Ceftazidime-Avibactam Efficacious in Nosocomial Pneumonia

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Results support a role for ceftazidime-avibactam as a potential alternative to carbapenems in patients with nosocomial pneumonia (including ventilator-associated pneumonia) caused by Gram-negative pathogens.

Nonventilator Hospital-Acquired Pneumonia Highly Prevalent in Acute Care

Nonventilator Hospital-Acquired Pneumonia Highly Prevalent in Acute Care

Nonventilator hospital-acquired pneumonia is a significant burden in US acute care hospitals and poses a risk to nonelderly, non-intensive unit patients.

SHEA Releases Contact Precaution Guidelines for Multidrug-Resistant Infections

SHEA Releases Contact Precaution Guidelines for Multidrug-Resistant Infections

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A new expert guidance concerning contact precautions for multidrug resistant bacteria has been released.

Delaying Rotavirus Vaccination Until Discharge Leads to Missed Opportunities

Delaying Rotavirus Vaccination Until Discharge Leads to Missed Opportunities

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Study found that many hospitalized infants did not receive rotavirus vaccination before discharge and were no longer age-eligible for vaccination after discharge from the hospital.

Prevalence of MRSA in ICU Patients After State-Mandated Surveillance

Prevalence of MRSA in ICU Patients After State-Mandated Surveillance

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The prevalence of methicillin-resistant Staphylococcus aureus colonization did not decline after implementation of state-legislated active surveillance among critically ill adults.

Reducing Surgical Site Infections Using Telehealth Electronic Monitoring

Reducing Surgical Site Infections Using Telehealth Electronic Monitoring

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Following vascular reconstruction, patients will receive postdischarge care that includes telehealth electronic monitoring.

Antibiotics, Mechanical Bowel Preparation Associated With Reduced SSIs

Antibiotics, Mechanical Bowel Preparation Associated With Reduced SSIs

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Oral antibiotics combined with mechanical bowel preparation should be considered for all patients undergoing left-sided colorectal cancer resections.

Treatment of Neurologic Complications in Infective Endocarditis

Treatment of Neurologic Complications in Infective Endocarditis

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Mortality rates associated with infective endocarditis range from 16% to 25%, with the highest rates observed among patients with nosocomial healthcare-associated infective endocarditis.

Reported Penicillin Allergy Increases Risk of Surgical Site Infections

Reported Penicillin Allergy Increases Risk of Surgical Site Infections

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Penicillin allergy may compromise receipt of recommended antibiotic prophylaxis intended to prevent surgical site infections.

Enteral Gram-Negative Colonization Associated With New ICU Infections

Enteral Gram-Negative Colonization Associated With New ICU Infections

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Researchers concluded that risk of ICU acquired Gram-negative bacteria was low in mechanically ventilated patients receiving selective digestive tract decontamination.

Claims-Based Estimates Not Accurate for Sepsis Analysis

Claims-Based Estimates Not Accurate for Sepsis Analysis

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The study includes a large number of diverse hospitals which account for approximately 10% of all acute care hospitalizations in the United States in 2014.

Antibiotic Prophylaxis After C-Section Reduces Surgical Site Infections

Antibiotic Prophylaxis After C-Section Reduces Surgical Site Infections

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A study conducted at the University of Cincinnati Medical Center compares antibiotic prophylaxis treatment after cesarean section in 403 obese women.

Conjunctivitis More Common in Adult Women Than Men

Conjunctivitis More Common in Adult Women Than Men

Adult women have a higher prevalence of conjunctivitis than men.

Methicillin-Susceptible <i>Staphyloccocus aureus</i> Carriers Unlikely to Acquire MRSA

Methicillin-Susceptible Staphyloccocus aureus Carriers Unlikely to Acquire MRSA

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Study results can be used to support an antimicrobial stewardship policy discouraging empiric coverage for MRSA infections in a population of MSSA carriers.

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