There is currently a global outbreak of disseminated Mycobacterium chimaera related to the widely used surgical device LivaNova 3T heater-cooler unit contamination.
A recent microbiological surveillance study found that >10% of linens tested positive for the fungi Mucorales at 20% of the hospitals included in the study.
Many patients with health care-associated infections concerned about transmission.
Treatment strategies for late acute prosthetic joint infections should be individualized according to patients' age, comorbidities, clinical presentation, and microorganism causing the infection.
Drop in adverse drug events, injuries from falls prevented 8,000 deaths, saved 2.9 billion.
Candidemia and Clostridium difficile infection (CDI) are both common healthcare-associated infections with overlapping risk factors, and almost 1 in 10 patients with candidemia are coinfected with CDI.
Time to blood culture positivity (TTP) provided reliable information on the risk for infective endocarditis (IE) in patients with Staphylococcus aureus bacteraemia.
An investigation into an outbreak of NDM-producing Klebsiella pneumoniae across 2 Belgian hospitals identified an outpatient clinic as the likely common site of transfer and highlights the importance of infection control measures in outpatient settings.
Clostridium difficile is the most common cause of healthcare-associated infections, with as many as 500,000 cases occurring annually in the United States. Efforts to prevent transmission within hospitals typically focus on patients with symptomatic Clostridium difficile infection.
Antimicrobial Lock Solutions Are Cost-Effective for Preventing Central Line-Associated Bloodstream InfectionsJuly 20, 2018
Antimicrobial lock solutions are an effective clinical and cost-effective strategy for preventing central line-associated bloodstream infections.
Active failures in personal protective equipment use by healthcare personnel may potentially lead to self-contamination.
The rates of post-endoscopic infection within seven days vary from 1.1 per 1,000 procedures for screening colonoscopy to 3 per 1,000 procedures for osophagogastroduodenoscopies.
Although the Systemic Inflammatory Response Syndrome criteria have been used for decades to identify sepsis in patients with suspected infection, they have been re-evaluated in the Third International Consensus Definitions for Sepsis and Septic Shock.
No clear relationship was found between the average daily area under concentration-time curve and mycologic response for micafungin in neonates.
Increasing costs associated with hospitalizations involving MSSA infection are expected to surpass national costs for hospitalizations associated with MRSA.
Severe liver failure is the strongest predictive factor of mortality related to infectious endocarditis in patients with liver cirrhosis.
Researchers assessed the ability of environmental screening as a proxy for patient colonization to reduce transmission of MRSA and VRE in nursing facilities.
As a result of the tests, the FDA is advising consumers and clinicians to avoid using all lots of Remedy Essentials No-Rinse Cleansing Foam.
Deployment-related trauma infectious complications continue after initial hospital discharge and into Veterans Affairs healthcare.
Findings do not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods, with third-generation or fourth-generation cephalosporins, piperacillin-tazobactam, and carbapenems reduces the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.
Over the last 9 years, there was an increase in the number of endocarditis cases, which mirrored the increase in concomitant use of mixed drugs.
Training on adherence to guidelines, the development of guidelines specific to the pediatric population, and the employment of tools and techniques to decrease contamination of blood cultures could decrease the overuse of blood cultures.
Pharmacists are increasingly becoming involved in antibiotic surveillance, including e-surveillance methods; formulation of antibiotic-use policies; and day-to-day control of problematic antibiotic use.
It is important to understand the relative severity of CDI in patients in the ICU because it effects treatment decisions. However, primary prevention remains a vitally important strategy to limit morbidity and mortality related to CDI in this vulnerable patient population.
Optimal management for severely ill patients with right-sided infective endocarditis (RSIE) remains challenging. The goal of this study was to determine outcome and associated prognostic factors in a population of ICU patients with RSIE.
A large proportion of surgical site infections are caused by organisms resistant to prophylactic antibiotics, with the greatest apparent burden in low- and middle-income countries
In this systematic review and meta-analysis, patients with infective endocarditis with vegetations greater than 10mm in size had significantly increased risk of systemic embolism and mortality.
The FDA has approved the use of Avycaz (ceftazidime, avibactam) to treat hospital-acquired bacterial pneumonia.
Although removal of orthopedic implants is considered to be associated with low risk of infection, higher rates of surgical site infection following these procedures have been reported.
Results support a role for ceftazidime-avibactam as a potential alternative to carbapenems in patients with nosocomial pneumonia (including ventilator-associated pneumonia) caused by Gram-negative pathogens.
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