The 13-valent pneumococcal conjugate vaccine prevents acute otitis media caused by Streptococcus pneumoniae.
The early addition of a second anti-MRSA antibiotic to vancomycin may reduce mortality in severe cases of influenza-MRSA co-infection in children.
Circumcision was associated with decreased risk of UTI in boys with hydronephrosis.
Although Epstein-Barr virus (EBV) acquisition in childhood is preferable to adolescence in terms of illness severity, early HBV infection may increase the risk of developing chronic EBV-related diseases.
Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.
Accurate and rapid diagnostics methods are needed to inform initial clinical decision making for patients with hip monoarthritis.
Investigators retrospectively reviewed the patients' medical records and MRI images and assessed the associations between the MRI findings and neurologic outcomes, specifically neurodevelopmental achievement, epilepsy, and sensorineural hearing loss.
Study showed that DTPa-HBV-IPV/Hib and PHiD-CV coadministered with MenACWY-TT in infants and toddlers were immunogenic with an acceptable reactogenicity profile.
In this whole-population study, researchers demonstrated a 22% vaccine effect of the 10-valent pneumococcal conjugate vaccine on all-cause acute otitis media.
The UTICalc calculator can be used to guide testing and treatment in children with suspected urinary tract infection.
A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.
The sBLA included clinical data from a Phase 4 study that enrolled nearly 2000 children and assessed the safety and immunogenicity of the 0.5mL dose.
Researchers found being born in an odd calendar year, especially in the winter or fall seasons, emerged as a risk factor for rotavirus in the postvaccine era in the United States.
A series of reported cases shows that the range of associated clinical manifestations is heterogeneous in chronic nonbacterial osteomyelitis or chronic recurrent multifocal osteomyelitis.
Cross-sectional survey represents the first assessment of antimicrobial prescription practices for prophylaxis in pediatric patients hospitalized worldwide.
The FDA has granted Breakthrough Therapy designation to Trumenba for immunization caused by Neisseria meningitidis group B in children.
The model developed accurately predicted which patients may need further testing based on clinical variables, and who may need antibiotics therapy based on urine analysis supplement.
MF59 adjuvanted, quadrivalent influenza vaccine (aQIV) was found to be more efficacious in preventing influenza than a non-adjuvanted conventional influenza vaccine in children aged 6 through 23 months.
The morphology of the lesions included erythematous papules, pseudovesicles, and plaques, with associated pain in 2 and pruritus in 3 patients; systemic symptoms ranged from none to low‐grade fevers, upper respiratory symptoms, and joint pain.
Findings provide an alternative explanation for virus acquisition and shedding in seroimumne pregnant women that contrasts with proposed mechanisms that argue that reactivation of persistent infection in seroimmune women leads to infection and virus shedding.
Compared with the general population, children with autism spectrum disorder and their younger siblings are undervaccinated.
Study evaluated the immunogenicity and safety of 1 and 2 doses of the quadrivalent meningococcal serogroups A, C, W, Y tetanus toxoid-conjugate vaccine in individuals with functional or anatomic asplenia.
Implementation of the sepsis calculator in daily clinical decision-making may be feasible in conjunction with existing protocols, with high adherence.
Use of oseltamivir does not appear to increase the risk of suicide in pediatric patients.
Infantile immunization rates were higher among children whose caregivers received compliance-linked incentives when compared to those who received only mobile phone reminders and those who received no intervention.
Investigators assessed the need for conducting routine voiding cystourethrograms in infants diagnosed with urinary tract infection.
As long-term neurocognitive deficits can occur as a result of severe malaria, researchers assessed the potential neuroprotective effect of inhaled nitric oxide on children with the infection.
This will be the first systematic review and meta-analysis on risk factors for pneumonia among neonates in India.
Newborns receiving the oral human neonatal rotavirus vaccine (RV3-BB) with the first dose occurring either at birth or at 8 weeks experienced fewer cases of severe rotavirus gastroenteritis than those treated with placebo.
In the overall comparative meta-analyses, the multicomponent meningococcal serogroup B vaccine had increased immunogenicity (short-term and persistent) compared with recombinant meningococcal serogroup B vaccine against strain NZ98/254.
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Infectious Disease Advisor Articles
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- PCV13 Prevents Acute Otitis Media Caused by S pneumoniae in Children
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- Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy
- Mosaic HIV-1 Vaccine Induces Responses in Humans and Monkeys
- FDA Announces New Drug Shortages Task Force