Pneumonia

Benzodiazepine Use May Increase Risk for Pneumonia

Benzodiazepine Use May Increase Risk for Pneumonia

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Patients who either are currently or have recently taken benzodiazepines may have an increased risk for pneumonia.

Bacterial Pneumonia-Complicating Influenza: Risks, Morbidity, and Mortality

Bacterial Pneumonia-Complicating Influenza: Risks, Morbidity, and Mortality

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Diagnosing coinfection in pneumonia can be challenging because of timing of the sample collection and false-negative results when the viruses replicate in the lower respiratory tract.

Worse Outcomes in Community-Acquired Pneumonia Linked to Higher FGF21 Levels

Worse Outcomes in Community-Acquired Pneumonia Linked to Higher FGF21 Levels

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Patients diagnosed with community-acquired pneumonia with higher levels of fibroblast growth factor-21 may have higher mortality rates and longer hospitalizations.

Trial Results Affected by Heterogeneous CAP Inclusion Criteria

Trial Results Affected by Heterogeneous CAP Inclusion Criteria

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The diagnostic criteria for community acquired pneumonia within randomized controlled trials are highly heterogeneous.

Rx Opioids Up Pneumonia Risk in Patients With, Without HIV

Rx Opioids Up Pneumonia Risk in Patients With, Without HIV

Risk greatest with higher-dose opioids and opioids with immunosuppressive properties

Child Pneumonia Rate Dropped Globally From 2000 to 2015

Child Pneumonia Rate Dropped Globally From 2000 to 2015

Number of clinical pneumonia episodes in children 5 years reduced 22 percent in developing countries.

Influenza Seroconversion Risk Factors in Adults Hospitalized for Pneumonia

Influenza Seroconversion Risk Factors in Adults Hospitalized for Pneumonia

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Adults hospitalized for pneumonia who received an influenza vaccination during their stay were less likely to seroconvert if they had diabetes, bacterial detection, baseline seropositive titers for influenza B, or influenza vaccination in the previous season.

Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals

Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals

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Compared with those at children's hospitals, children receiving CAP care at other hospital types are less likely to be treated as per national guidelines.

Pneumococcal Vaccine May Reduce Resistant <i>Streptococcus Pneumoniae</i> Carriage

Pneumococcal Vaccine May Reduce Resistant Streptococcus Pneumoniae Carriage

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A marked and rapid reduction in PCV13 serotype, the most common antibiotic-nonsusceptible S pneumoniae, carriage was observed in both ethnic populations included in this study.

Worse Outcomes From <i>Legionella</i> Pneumonia in Individuals With Advanced HIV

Worse Outcomes From Legionella Pneumonia in Individuals With Advanced HIV

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Previous results stated that Legionella pneumonia characteristics may not differ between individuals with HIV and individuals who do not have HIV.

Combining Corticosteroids and Antibiotics May Be Cost-Effective in CAP

Combining Corticosteroids and Antibiotics May Be Cost-Effective in CAP

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Treating severe community-acquired pneumonia with a combination of corticosteroids and antibiotics may be a cost-effective strategy.

<i>Klebsiella pneumoniae</i> With PKS Gene Cluster Increases 30-Day Mortality

Klebsiella pneumoniae With PKS Gene Cluster Increases 30-Day Mortality

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Results showed pks carriage by a causative strain was an independent risk factor for 30-day mortality in patients with K pneumoniae bloodstream infections, especially when accompanied by MDR.

Invasive Pneumococcal Disease Risk Higher in Premature Infants

Invasive Pneumococcal Disease Risk Higher in Premature Infants

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Invasive pneumococcal disease was significantly higher in premature infants than in infants born at term.

Guideline Adoption for Childhood Community-Acquired Pneumonia

Guideline Adoption for Childhood Community-Acquired Pneumonia

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Recommendations in line with the current national guidelines for childhood CAP were found to be supported at pediatric primary care practices.

PCV13 Vaccine Protects Against Serotype 3 Invasive Pneumococcal Disease in Children

PCV13 Vaccine Protects Against Serotype 3 Invasive Pneumococcal Disease in Children

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A meta-analysis of case-control studies supports the use of the 13-valent pneumococcal conjugate vaccine in children as it protects against serotype 3.

IDSA/ATS CAP Guidelines Have Poor Specificity/Sensitivity for Some Bacteria

IDSA/ATS CAP Guidelines Have Poor Specificity/Sensitivity for Some Bacteria

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Recommended indications for Streptococcus pneumoniae and Legionella pneumophila antigen testing for CAP have poor sensitivity and specificity for identifying patients to screen.

Pneumococcal Vaccine Recommendations Cause Confusion Among Physicians

Pneumococcal Vaccine Recommendations Cause Confusion Among Physicians

While primary care physicians overwhelmingly recommend pneumococcal vaccines, there is a gap in their knowledge of how to implement related vaccine recommendations.

Epidemiology of <i>K pneumoniae</i> Carbapenemase-Producing Enterobacteriaceae Infections in Children

Epidemiology of K pneumoniae Carbapenemase-Producing Enterobacteriaceae Infections in Children

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Patients with Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae infections have multisystem disease and exposure to carbapenems and aminoglycosides.

Risk Factors for Multidrug-Resistant Pathogens in Pneumonia

Risk Factors for Multidrug-Resistant Pathogens in Pneumonia

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Previous antibiotic use and mechanical invasive ventilation were risk factors for multidrug-resistant pathogens in hospital-associated or ventilator-associated pneumonia.

Pneumococcal <i>H Influenzae</i> Protein D Conjugate Vaccine Effective in Children

Pneumococcal H Influenzae Protein D Conjugate Vaccine Effective in Children

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The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.

Antipseudomonal Monotherapy Efficacious in Pneumonia

Antipseudomonal Monotherapy Efficacious in Pneumonia

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Antipseudomonal combination therapy has shown poorer efficacy than antipseudomonal monotherapy in individuals with suspected pseudomonal pneumonia.

PCV13 in Young Adults With Diabetes Could Avert Pneumonia Hospitalizations

PCV13 in Young Adults With Diabetes Could Avert Pneumonia Hospitalizations

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PCV13 in adults age <65 years with diabetes could reduce a substantial number of pneumonia hospitalizations.

Omadacycline Approved for  Community-Acquired Bacterial Pneumonia, Skin Infections

Omadacycline Approved for Community-Acquired Bacterial Pneumonia, Skin Infections

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The approval was based on Phase 3 data from 2 studies in ABSSSI, where treatment with Nuzyra was compared with linezolid, and 1 study in CABP comparing Nuzyra with moxifloxacin. Across all 3 trials, Nuzyra was found to be effective and generally safe and well-tolerated.

Antibiotic Stewardship May Aid Stepdown Therapies for Community-Acquired Pneumonia

Antibiotic Stewardship May Aid Stepdown Therapies for Community-Acquired Pneumonia

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The use of fluoroquinolones in stable patients with community-acquired pneumonia can be reduced with stewardship programs that share antibiotic use data and provide guidance for step-down therapy.

Improving Rates of Combination Pneumococcal Vaccination in Patients With SLE

Improving Rates of Combination Pneumococcal Vaccination in Patients With SLE

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Pneumococcal vaccination rates in patients with systemic lupus erythematosus improved significantly after the implementation of a multifaceted intervention at a rheumatology practice.

Chest Radiograph Effective for Excluding Pediatric Pneumonia

Chest Radiograph Effective for Excluding Pediatric Pneumonia

A negative chest radiograph accurately excludes pneumonia in the majority of children.

Positive Results for Ceftolozane/Tazobactamin Phase 3 Study of Ventilated HABP, VABP Patients

Positive Results for Ceftolozane/Tazobactamin Phase 3 Study of Ventilated HABP, VABP Patients

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The full findings from the study will be presented at a future scientific conference; Merck plans to include the data in a supplemental New Drug Application for Zerbaxa which will be submitted to the Food and Drug Administration.

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

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Influenza proved to be an independent risk factor for invasive pulmonary aspergillosis.

Therapeutic Algorithm May Guide Empiric Therapy in Pneumonia

Therapeutic Algorithm May Guide Empiric Therapy in Pneumonia

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An algorithm based on risk factors for resistant pathogens and illness severity can simplify pneumonia treatment, improve the accuracy of empiric therapy, reduce mortality, and help avoid overusing broad spectrum therapy in some patients.

Long-Term PPI Use Linked to Pneumonia Risk in Older Adults

Long-Term PPI Use Linked to Pneumonia Risk in Older Adults

Rate of incident pneumonia increased in second year after initiating treatment with proton pump inhibitors

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