Clinicians should consider these findings when using atypical antipsychotics in patients at risk for pneumonia.
Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.
In the LEAP 2 study (N=738), patients with moderate CABP received either oral lefamulin 600mg every 12 hours for 5 days or oral moxifloxacin 400mg once daily for 7 days.
Study showed that DTPa-HBV-IPV/Hib and PHiD-CV coadministered with MenACWY-TT in infants and toddlers were immunogenic with an acceptable reactogenicity profile.
Low-dose computed tomography may assist clinicians in modifying diagnosis of elderly patients who are admitted with suspected pneumonia.
Clinical presentation and outcomes in HIV-infected patients with Legionella pneumonia did not differ from patients without HIV infection.
In this whole-population study, researchers demonstrated a 22% vaccine effect of the 10-valent pneumococcal conjugate vaccine on all-cause acute otitis media.
Deployment-related trauma infectious complications continue after initial hospital discharge and into Veterans Affairs healthcare.
In this review, David C. Helfgott, MD, editorial advisory board member for Infectious Disease Advisor, focuses on infectious complications from the use of monoclonal antibodies for malignancy.
A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.
The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.
Researchers found increased myocardial infarction rates during the week after Streptococcus pneumoniae and influenza infections.
Differences in serum inflammatory markers may exist between patients with community-acquired pneumonia who present within the first 48 hours of symptom onset vs those who present later.
Adults with community-acquired pneumonia that is visualized on CT scan but not on concurrent chest radiograph have similar pathogens, disease severity, and outcomes as patients who had pneumonia confirmed via chest radiograph.
Omadacycline met all required FDA and European Medicines Agency primary endpoints in each study and demonstrated a generally safe and well-tolerated profile.
Researchers retrospectively analyzed data from patients hospitalized with pneumococcal community-acquired pneumonia to determine risk factors for pneumococcal bacteremia.
Researchers assessed the timing of azithromycin administration for pediatric community-acquired pneumonia to determine its effectiveness in the setting of macrolide resistance.
Community-acquired pneumonia and other acute infections can cause or exacerbate cardiovascular complications.
Use of prophylactic antimicrobial therapy was not associated with a reduction in mortality or transfer to critical care compared with patients managed with supportive care only.
Researchers investigated the prognostic and pathogenetic effect of angiopoietins in regulating pulmonary vascular barrier function and inflammation in bacterial pneumonia.
In protecting senior Veterans Health Administration patients against influenza- or pneumonia-associated hospitalization, high-dose influenza vaccine was more effective than standard-dose vaccine.
The utilization of this tool could prevent severe complications secondary to delayed pneumonia diagnosis and treatment.
MRSA nares screening can be a stewardship tool to streamline empiric antibiotic therapy among those not nares colonized with MRSA.
This will be the first systematic review and meta-analysis on risk factors for pneumonia among neonates in India.
Patients admitted to hospitals with severe CAP who subsequently required invasive mechanical ventilation had a higher mortality risk.
Opioid use is associated with elevated risk of invasive pneumococcal disease.
Researchers found a strong link between prescription opioid use and the risk for invasive pneumococcal disease (IPD). The strongest link was present in individuals using formulations of opioids that were long-acting, highly potent, or utilized at a high dose.
The FDA has approved the use of Avycaz (ceftazidime, avibactam) to treat hospital-acquired bacterial pneumonia.
Study analyzed the trends of nasopharyngeal carriage and antibiotic resistance of Streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrhalis isolated from young children with acute otitis media during a 16-year period.
A single dose of PCV13 was found to be effective in generating a small, temporary reduction in vaccine-type nasopharyngeal pneumococcal carriage in older, community-dwelling residents.
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Infectious Disease Advisor Articles
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