Pregnancy

Novel Vaccine for Pregnancy-Associated Malaria Is Well Tolerated

Novel Vaccine for Pregnancy-Associated Malaria Is Well Tolerated

By

A novel malaria vaccine candidate is well tolerated and induced functionally active antibodies.

Adverse Birth Outcomes Up for Women With H1N1 Flu in ICU

Adverse Birth Outcomes Up for Women With H1N1 Flu in ICU

Pregnant women admitted to ICU with flu more likely to deliver preterm infants, low birth-weight infants.

Breast Milk Pasteurization Decreased Postnatal Cytomegalovirus

Breast Milk Pasteurization Decreased Postnatal Cytomegalovirus

By

The short-term pasteurization of breast milk from mothers with CMV significantly decreased such infections in very preterm infants.

Syphilis Rates Increasing in Peripartum Women in the United States

Syphilis Rates Increasing in Peripartum Women in the United States

By

The rate of syphilis has been increasing in peripartum women in the United States.

Sequential Prenatal, Postnatal Neuroimaging in Zika-Exposed Infants

Sequential Prenatal, Postnatal Neuroimaging in Zika-Exposed Infants

By

Sequential neuroimaging indicated that prenatal and postnatal ultrasonography may identify Zika virus-related brain injury in most patients.

Association of Hydrocephalus With Congenital Zika Syndrome

Association of Hydrocephalus With Congenital Zika Syndrome

By

Evidence that hydrocephalus is a complication in at least a proportion of patients with congenital Zika syndrome has been published in JAMA Neurology.

Bacterial Vaginosis Treatment Does Not Reduce Late Miscarriages, Preterm Birth

Bacterial Vaginosis Treatment Does Not Reduce Late Miscarriages, Preterm Birth

By

No evidence for reduction in risk for late miscarriage or spontaneous preterm birth as a result of screening and treatment for bacterial vaginosis.

Prenatal Malaria Exposure Modulates Innate Immune Responses at Birth

Prenatal Malaria Exposure Modulates Innate Immune Responses at Birth

By

Placental malaria has a profound effect on the fetal immune system, and prenatal malaria exposure categories may drive heterogeneity to malaria susceptibility.

Biomarkers Associated With Zika Virus Fetal Abnormalities

Biomarkers Associated With Zika Virus Fetal Abnormalities

By

An analysis of 69 cytokines found 3 specific chemokines that are specifically associated with symptomatic Zika virus infection during pregnancy.

Pregnant Women Commonly Refuse Vaccines

Pregnant Women Commonly Refuse Vaccines

Providers believe stressing fetal protection is most effective strategy against refusal.

Neonatal Antibody Concentration After Third Trimester Tdap Vaccination

Neonatal Antibody Concentration After Third Trimester Tdap Vaccination

By

Immunization of mothers during the 3rd trimester with Tdap vaccine linked with higher neonatal concentrations of pertussis toxin antibodies compared with no immunization.

Labeling for Two HIV Drugs Updated With Safety, PK Data for Pregnant Patients

Labeling for Two HIV Drugs Updated With Safety, PK Data for Pregnant Patients

By

The "8.1 Pregnancy" and "12.3 Pharmacokinetics" sections have been updated with data showing no increase in the risk of overall major birth defects with 1st trimester exposure for rilpivirine.

Optimal Pertussis Toxin Antibodies Achieved With Third Trimester Tdap Vaccination

Optimal Pertussis Toxin Antibodies Achieved With Third Trimester Tdap Vaccination

Immunization with Tdap vaccine during the third trimester of pregnancy resulted in higher concentrations of pertussis toxin antibodies in newborns.

Contraceptive Use Inadequate Among Young Women With HIV

Contraceptive Use Inadequate Among Young Women With HIV

By

Effective contraception, condoms, and dual method use was inadequately low in a cohort of young HIV-positive women.

Sustained Follow-Up Essential for Infants of Women Exposed to Zika Virus

Sustained Follow-Up Essential for Infants of Women Exposed to Zika Virus

By

Approximately 14% of children who were born to mothers with confirmed or possible Zika virus infection during pregnancy were identified during infancy or early childhood as having a Zika-associated birth defect.

CDC Updates Guidance for Post-Zika Virus Exposure Counseling in Males

CDC Updates Guidance for Post-Zika Virus Exposure Counseling in Males

By

In an updated interim guidance, the CDC now recommends that couples wait at least 3 months before attempting to conceive after possible Zika virus exposure in the male.

Safety and Immunogenicity of Tdap Vaccine Immunization During Pregnancy

Safety and Immunogenicity of Tdap Vaccine Immunization During Pregnancy

By

Immunization with Tdap vaccine during pregnancy results in higher levels of antibodies early in infancy but lower levels after the primary vaccine series.

Comparison of Live Attenuated vs Inactive Influenza Vaccine in Nursing Mothers

Comparison of Live Attenuated vs Inactive Influenza Vaccine in Nursing Mothers

By

Both LAIV and IIV are safe for nursing mothers, however, breast milk and serum antibody responses were higher for IIV.

Amniotic Fluid Is Sterile in Uncomplicated Term Pregnancies

Amniotic Fluid Is Sterile in Uncomplicated Term Pregnancies

Fetal development in uncomplicated pregnancies occurs in the absence of amniotic fluid microbiota and offspring microbial colonization starts after uterine contractions and rupture of amniotic membrane.

HSV-1 and HSV-2 Seroprevalence Among Pregnant Women in the United States

HSV-1 and HSV-2 Seroprevalence Among Pregnant Women in the United States

By

Further investigation into new strategies to prevent herpes simplex virus (HSV) acquisition in pregnant women and to prevent HSV transmission from mother to neonate are warranted.

Risk of Adverse Birth Outcomes in Women With HIV Using Tenofovir-Emtricitabine

Risk of Adverse Birth Outcomes in Women With HIV Using Tenofovir-Emtricitabine

By

The number of adverse birth outcomes was not higher with tenofovir, emtricitabine, and ritonavir-boosted lopinavir than with zidovudine, lamivudine, and ritonavir-boosted lopinavir or tenofovir, emtricitabine, and ritonavir-boosted atazanavir in HIV-infected women and their infants in the United States.

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

By

This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.

About Half of Pregnant Women With HIV Have C-Sections

About Half of Pregnant Women With HIV Have C-Sections

About half of pregnant women with HIV infection underwent cesarean delivery between 1998 and 2013.

Risk Factors for Cytomegalovirus Reinfections in Seropositive Women

Risk Factors for Cytomegalovirus Reinfections in Seropositive Women

By

Findings provide an alternative explanation for virus acquisition and shedding in seroimumne pregnant women that contrasts with proposed mechanisms that argue that reactivation of persistent infection in seroimmune women leads to infection and virus shedding.

CDC Recommends Additional Malaria Treatment Option During Pregnancy

CDC Recommends Additional Malaria Treatment Option During Pregnancy

By

Women in the United States with uncomplicated malaria during the first trimester of pregnancy should be treated with the currently recommended options of either mefloquine or quinine plus clindamycin. However, when neither of these options is available, artemether-lumefantrine should be considered for treatment.

HIV-1 Susceptibility Increases in Late Pregnancy and Postpartum Periods

HIV-1 Susceptibility Increases in Late Pregnancy and Postpartum Periods

By

Researchers assessed the differential risk of acquiring HIV-1 infection across reproductive stages by calculating per-coital-act risk for each stage and comparing with nonpregnant times.

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

By

Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Maternal receipt of influenza and tetanus toxoid, reduced diphtheria toxoid, and Tdap vaccines is not associated with infant hospitalization or death.

Chlamydia Infection Not Associated With Adverse Birth Outcomes

Chlamydia Infection Not Associated With Adverse Birth Outcomes

By

A chlamydia infection that has been identified during pregnancy and treated does not appear to result in a substantial increase in the risk of preterm birth compared with the risk in women tested and shown to not have a chlamydia infection.

Antibiotic Prescribing Habits for UTI in Pregnant Women

Antibiotic Prescribing Habits for UTI in Pregnant Women

By

For pregnant women in their first trimester, a 2011 Committee Opinion from the ACOG recommended that sulfonamides and nitrofurantoin may be prescribed only if other antimicrobial therapies are deemed clinically inappropriate.

Sign Up for Free e-newsletters