Pregnancy

About Half of Pregnant Women With HIV Have C-Sections

About Half of Pregnant Women With HIV Have C-Sections

About half of pregnant women with HIV infection underwent cesarean delivery between 1998 and 2013.

Risk Factors for Cytomegalovirus Reinfections in Seropositive Women

Risk Factors for Cytomegalovirus Reinfections in Seropositive Women

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Findings provide an alternative explanation for virus acquisition and shedding in seroimumne pregnant women that contrasts with proposed mechanisms that argue that reactivation of persistent infection in seroimmune women leads to infection and virus shedding.

CDC Recommends Additional Malaria Treatment Option During Pregnancy

CDC Recommends Additional Malaria Treatment Option During Pregnancy

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Women in the United States with uncomplicated malaria during the first trimester of pregnancy should be treated with the currently recommended options of either mefloquine or quinine plus clindamycin. However, when neither of these options is available, artemether-lumefantrine should be considered for treatment.

HIV-1 Susceptibility Increases in Late Pregnancy and Postpartum Periods

HIV-1 Susceptibility Increases in Late Pregnancy and Postpartum Periods

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Researchers assessed the differential risk of acquiring HIV-1 infection across reproductive stages by calculating per-coital-act risk for each stage and comparing with nonpregnant times.

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

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Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.

No difference between tenofovir and placebo in reducing perinatal transmission of hepatitis B

Hepatitis B e-antigen positive mothers receiving tenofovir daily from 28-weeks gestation to 2 months postpartum did not show significant reductions in HBV transmission rates compared to placebo treated participants.

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Maternal receipt of influenza and tetanus toxoid, reduced diphtheria toxoid, and Tdap vaccines is not associated with infant hospitalization or death.

Maternal vaccination during pregnancy not associated with infant hospitalization, mortality

No significant association was identified between maternal intrapartum vaccination with the influenza or tetanus, diphtheria, and acellular pertussis (Tdap) vaccine and infant hospitalization or mortality.

Chlamydia Infection Not Associated With Adverse Birth Outcomes

Chlamydia Infection Not Associated With Adverse Birth Outcomes

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A chlamydia infection that has been identified during pregnancy and treated does not appear to result in a substantial increase in the risk of preterm birth compared with the risk in women tested and shown to not have a chlamydia infection.

Antibiotic Prescribing Habits for UTI in Pregnant Women

Antibiotic Prescribing Habits for UTI in Pregnant Women

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For pregnant women in their first trimester, a 2011 Committee Opinion from the ACOG recommended that sulfonamides and nitrofurantoin may be prescribed only if other antimicrobial therapies are deemed clinically inappropriate.

Tenofovir Use Safe During Pregnancy

Tenofovir Use Safe During Pregnancy

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Further research on longer-term effects of maternal prenatal TDF use is important given the majority of HIV-infected women are prescribed a TDF-containing prevention of mother-to-child transmission regimen.

New Recommendations for Managing Hepatitis C Infection During Pregnancy

New Recommendations for Managing Hepatitis C Infection During Pregnancy

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The recommendations will be published in the November issue of the American Journal of Obstetrics and Gynecology.

New ART Recommendations for Pregnant Women With HIV

New ART Recommendations for Pregnant Women With HIV

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The GRADE framework recommendations provide guidance for combination treatment regimens based on 2 systemic reviews, patient considerations, fetal outcomes, and practical issues.

Link Between Influenza Vaccine, Spontaneous Abortion Further Clarified

Link Between Influenza Vaccine, Spontaneous Abortion Further Clarified

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Pregnant women who received vaccines containing the pH1N1 antigen for 2 consecutive influenza seasons may have increased risk for spontaneous abortion 28 days postvaccination.

HPV Vaccine Does Not Increase Risk for Adverse Maternal, Infant Outcomes

HPV Vaccine Does Not Increase Risk for Adverse Maternal, Infant Outcomes

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Inadvertent administration of the quadrivalent HPV vaccine during periconception or pregnancy was not associated with additional risk to mothers and their infants.

Viral Load Rebound Seen After HIV Suppression in Pregnancy

Viral Load Rebound Seen After HIV Suppression in Pregnancy

Women achieving HIV viral suppression in pregnancy can experience viral load rebound predelivery.

Risk of Congenital Malformations With Gestational Antibiotic Use

Risk of Congenital Malformations With Gestational Antibiotic Use

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The use of specific antibiotics during pregnancy may be associated with increased risk for major congenital malformations.

Prior Maternal Flu Vaccination Does Not Affect Newborn Antibody Titers

Prior Maternal Flu Vaccination Does Not Affect Newborn Antibody Titers

Prior influenza vaccination predicts higher baseline antibody titers and decreased peak antibody responses against all influenza strains in pregnant women.

Influenza Vaccination During Pregnancy Reduces Infant Risk for Acute Lower Respiratory Infection

Influenza Vaccination During Pregnancy Reduces Infant Risk for Acute Lower Respiratory Infection

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Influenza vaccination during pregnancy decreases infant hospitalizations for all-cause acute lower respiratory tract infection during the first 3 months of life.

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

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Cytomeglovirus infection is associated with a range of diagnostic and treatment challenges and a relatively high transmission rate from the mother to the fetus.

Telbivudine During Early Pregnancy Prevents HBV Transmission

Telbivudine During Early Pregnancy Prevents HBV Transmission

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A study showed that telbivudine administered during early and middle pregnancy prevented transmission of hepatitis B virus infection from mother to infants in all participants receiving antiviral treatment.

Can Testing Placental Tissue Confirm Zika Infection?

Can Testing Placental Tissue Confirm Zika Infection?

Zika infection can be ruled out or confirmed by testing fetal and placental tissue according to a study published in Morbidity and Mortality Weekly Report.

No Elevated Malformations Risk, Low Birth Weight With Maternal Dengue

No Elevated Malformations Risk, Low Birth Weight With Maternal Dengue

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Epidemiological study finds reassuring outcomes for Brazilian babies born to mothers with symptomatic dengue during pregnancy.

Rate of Birth Defects Nearly 5% With Zika Confirmed Pregnancies

Rate of Birth Defects Nearly 5% With Zika Confirmed Pregnancies

About 1 in 20 women in the US territories who were infected with Zika during pregnancy had babies with possible Zika-associated birth defects.

Placental Malaria and Risk of Malaria Infection in Childhood

Placental Malaria and Risk of Malaria Infection in Childhood

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Placental malaria during pregnancy may raise the risk of malaria infection in childhood by promoting maternal microchimerism, in which the fetus acquires noninherited maternal cells during pregnancy. Maternal microchimerism may be the mechanism by which the fetus develops tolerance to malaria antigens, leading to an impaired malaria-specific immune response.

 Knowledge of HCV Transmission in Opioid-Dependent Pregnant Women

Knowledge of HCV Transmission in Opioid-Dependent Pregnant Women

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Most opioid-dependent pregnant patients understand that intravenous drug use is a major transmission modality of hepatitis C virus.

Potential Exposure of Zika Infection Low in Pregnant Women

Potential Exposure of Zika Infection Low in Pregnant Women

US women traveling to active Zika virus areas may be less likely to get infected than expected.

Tenofovir During Pregnancy Prevents Prenatal Transmission of HBV

Tenofovir During Pregnancy Prevents Prenatal Transmission of HBV

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Women with a high hepatitis B viral load who receive tenofovir during pregnancy have a significantly reduced risk for passing on the virus to their child, without an increase in the risk of adverse events.

HIV Transmission Through Breastfeeding: New Review and Expert Interview

HIV Transmission Through Breastfeeding: New Review and Expert Interview

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Mother-to-child HIV transmission rates are low in the presence of antiretroviral therapy but increase once ART stops at 6 months postpartum.

Increase Risk of Spontaneous Abortion With Antibiotic Use

Increase Risk of Spontaneous Abortion With Antibiotic Use

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Using certain antibiotics during early pregnancy increases the risk of spontaneous abortion.

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