Prevention

WHO Issues Position Paper for Typhoid Fever Vaccine

WHO Issues Position Paper for Typhoid Fever Vaccine

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The World Health Organization recommends vaccination in cases of confirmed outbreaks of typhoid fever, although data on the use of vaccines in controlling outbreaks are very limited and research to assess the value of vaccination in these cases is strongly recommended.

MenACWY-TT Vaccine Can Be Effectively Coadministered With Routine Pediatric Immunizations

MenACWY-TT Vaccine Can Be Effectively Coadministered With Routine Pediatric Immunizations

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Study showed that DTPa-HBV-IPV/Hib and PHiD-CV coadministered with MenACWY-TT in infants and toddlers were immunogenic with an acceptable reactogenicity profile.

HPV Vaccination May Offer Protection Against Cervical Precancer

HPV Vaccination May Offer Protection Against Cervical Precancer

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The authors concluded, "There is high-certainty evidence that HPV vaccines protect against cervical precancer in adolescent girls and young women aged 15 to 26," while also indicated that future studies should have long-term follow-up.

Risk of Developing Multiple Sclerosis After HPV Vaccination

Risk of Developing Multiple Sclerosis After HPV Vaccination

Investigators sought to determine the link between HPV vaccination and the risk of developing multiple sclerosis.

The 'Attitude Roots' Underlying Antivaccination Beliefs

The 'Attitude Roots' Underlying Antivaccination Beliefs

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Although efforts to debunk antivaccination beliefs often rely on fact-based strategies, emerging evidence suggests it may be more effective to target the psychological roots of these beliefs.

Are Vaccines Associated With Multiple Sclerosis Relapse?

Are Vaccines Associated With Multiple Sclerosis Relapse?

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Researchers found there are no associations between vaccinations and multiple sclerosis relapse flares.

Season and Year of Birth an Emergent Risk Factor for Rotavirus

Season and Year of Birth an Emergent Risk Factor for Rotavirus

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Researchers found being born in an odd calendar year, especially in the winter or fall seasons, emerged as a risk factor for rotavirus in the postvaccine era in the United States.

MenB Vaccine Gets Breakthrough Therapy Designation for Children Ages 1-9 Years

MenB Vaccine Gets Breakthrough Therapy Designation for Children Ages 1-9 Years

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The FDA has granted Breakthrough Therapy designation to Trumenba for immunization caused by Neisseria meningitidis group B in children.

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists are increasingly becoming involved in antibiotic surveillance, including e-surveillance methods; formulation of antibiotic-use policies; and day-to-day control of problematic antibiotic use.

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed

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From January to March 2017, the researchers distributed a cross-sectional online survey to all physicians in the Division of General Internal Medicine and Clinical Innovation at NYULH, across 5 different practice settings. A total of 138 (out of 530) responded (26%).

Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

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The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

Vaccine Lessens Incidence of Herpes Zoster Complications in Immuncompetent Older Adults

Vaccine Lessens Incidence of Herpes Zoster Complications in Immuncompetent Older Adults

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Researchers reviewed clinical trial data to evaluate the efficacy of herpes zoster subunit vaccine in preventing complications, hospitalizations, and deaths.

Respiratory Syncytial Virus Prevention and Asthma in Preterm Infants

Respiratory Syncytial Virus Prevention and Asthma in Preterm Infants

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Researchers assessed the relationship between prevention of RSV in preterm infants and the frequency of subsequent wheeze in childhood.

1980 to 2014 Saw Decrease in US Mortality From Infectious Diseases

1980 to 2014 Saw Decrease in US Mortality From Infectious Diseases

There were declines in mortality from most categories of infectious diseases, with large differences among US counties. However, over this time there was an increase in mortality for diarrheal diseases.

Oral Bivalent Whole-Cell Cholera Vaccine Efficacy Over 5 Years

Oral Bivalent Whole-Cell Cholera Vaccine Efficacy Over 5 Years

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Researchers found that oral cholera vaccine efficacy was statistically significantly higher when administered to children 5 and older compared with children younger than 5, a difference that had been suspected but not conclusively demonstrated in previous trials.

Inactivity, Prolonged Sitting Tied to Urinary Tract Infections in Men

Inactivity, Prolonged Sitting Tied to Urinary Tract Infections in Men

Result supports the importance of both reducing sitting time and promoting physical activity for preventing lower urinary tract symptoms.

Rotavirus Vaccines Reduce Hospitalizations of Low Birth Weight Infants

Rotavirus Vaccines Reduce Hospitalizations of Low Birth Weight Infants

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Rotavirus vaccines are effective in reducing rates of acute gastroenteritis and rotavirus hospitalizations among low birth weight and very low birth weight children.

Vaccine-Derived Immune Protection Against Mumps Wanes

Vaccine-Derived Immune Protection Against Mumps Wanes

Vaccine-derived immune protection against mumps wanes on average 27 years after vaccination.

HPV Vaccination: Should Adolescents Be Allowed to Give Consent?

HPV Vaccination: Should Adolescents Be Allowed to Give Consent?

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Adolescent consent may help minimize delays in vaccination and reduce the overall incidence of cervical, oropharyngeal, and anal cancers.

Myopericarditis Risk in Adults Following Live Viral Vaccination Rare

Myopericarditis Risk in Adults Following Live Viral Vaccination Rare

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Findings confirm that cardiovascular complications related to commonly-administered, live viral vaccination are rare in adults.

Fractional Yellow Fever Vaccine Dose Stimulated Effective Immune Response

Fractional Yellow Fever Vaccine Dose Stimulated Effective Immune Response

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The use of fractional doses of yellow fever vaccine could reduce the amount of yellow fever vaccine for reactive campaigns and provide flexibility in management of global stockpile of yellow fever vaccine when outbreaks occur.

Effect of Vaccine Antigen Exposure in First 23 Months of Life

Effect of Vaccine Antigen Exposure in First 23 Months of Life

The estimated cumulative vaccine antigen exposure through age 23 months does not differ significantly for children with vs those without hospital visits for infectious diseases not targeted by vaccines from age 24 to 47 months.

Measles Vaccination After Third Dose of DTP Vaccine May Improve Child Survival

Measles Vaccination After Third Dose of DTP Vaccine May Improve Child Survival

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Measles vaccination, administered in the recommended sequence, is associated with improved child survival and may have contribute to the achievement of Millennium Development Goal 4.

Marijuana, Alcohol Intervention May Help to Reduce STIs Among Adolescents

Marijuana, Alcohol Intervention May Help to Reduce STIs Among Adolescents

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Behavioral interventions that include sexual risk reduction combined with alcohol- and cannabis-focused elements are effective in reducing STI incidence among adolescents.

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Maternal receipt of influenza and tetanus toxoid, reduced diphtheria toxoid, and Tdap vaccines is not associated with infant hospitalization or death.

Safety Profile of Investigational RSV Vaccine Similar to Tdap Vaccine

Safety Profile of Investigational RSV Vaccine Similar to Tdap Vaccine

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All formulations of a respiratory syncytial virus (RSV) candidate vaccine were able to boost RSV antibody titers and their safety profile was similar to the Tdap vaccine.

Oral neonatal rotavirus vaccine RV3-BB effective in preventing severe gastroenteritis

Newborns receiving the oral human neonatal rotavirus vaccine (RV3-BB) with the first dose occurring either at birth or at 8 weeks experienced fewer cases of severe rotavirus gastroenteritis than those treated with placebo.

Third Trimester Maternal Vaccination Against Pertussis Protective for Infants

Third Trimester Maternal Vaccination Against Pertussis Protective for Infants

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Maternal vaccination against pertussis between 27 and 36 weeks of gestation was associated with a high percentage of newborns with protective pertussis antibody concentrations.

ACIP Votes in Favor of Heplisav-B for Hepatitis B Prevention in Adults

ACIP Votes in Favor of Heplisav-B for Hepatitis B Prevention in Adults

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The FDA approval of Heplisav-B was based on data from 3 phase 3 noninferiority trials involving close to 10,000 adults who received the vaccine.

ACIP: New Recommendations for Herpes Zoster Vaccine Administration

ACIP: New Recommendations for Herpes Zoster Vaccine Administration

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The Advisory Committee on Immunization Practices has provided 3 new recommendations to supplement its original 2008 report, as well as a cost-effectiveness analysis from the CDC.

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