Diverse Patient Cohort Validates RAPID Score for Prognosis of Pleural Infections

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Gram-negative rod infections, heart disease, diabetes, cancer, lung disease, and increased length of stay correlated with high risk scores.
Gram-negative rod infections, heart disease, diabetes, cancer, lung disease, and increased length of stay correlated with high risk scores.

HealthDay News -- The recently developed RAPID score, which identifies the risk of mortality in patients with pleural infections based on five clinical factors, has been validated in a diverse patient cohort. The findings have been published online in the Annals of the American Thoracic Society.

Heath D. White, D., from Baylor Scott & White Health in Temple, Texas, and colleagues aimed to further validate the RAPID score in a diverse cohort including 187 patients with culture-positive pleural infections. 

Patients were classified into low-, medium-, and high-risk groups based on RAPID scores (0 to 2, 3 to 4, and 5 to 7, respectively). The researchers examined all-cause mortality at three months and at one, three, and five years.

The researchers found that the three-month mortality scores were 1.5, 17.8, and 47.8%, respectively, for low-, medium-, and high-risk groups, with increased odds for the medium- and high-risk groups (odds ratios, 14.3 and 53.3, respectively). At one, three, and five years, the trend continued. 

Gram-negative rod infections, heart disease, diabetes, cancer, lung disease, and increased length of stay correlated with high risk scores.

"When applied to a diverse patient cohort, the RAPID score predicts outcomes in patients up to five years and may aid in long term risk stratification on presentation," the authors write.

Reference

1. White HD, et al. Ann Amer Thor Soc. 2015; doi: 10.1513/AnnalsATS.201505-272OC. 

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