Respiratory

Feature Article

A Pan-Tuberculosis Regimen: The Debate Continues

A Pan-Tuberculosis Regimen: The Debate Continues

Last month the South Africa National Tuberculosis Program decided to make oral bedaqualine available for all rifampin-resistant TB (RR-TB) in place of — the often more toxic — injectable drugs.

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Severity of Acute Respiratory Infections in Children Affected by Viral Etiology

Severity of Acute Respiratory Infections in Children Affected by Viral Etiology

Viral etiology plays a significant role in symptom severity in children with acute respiratory infections, and associated with an enhanced risk for acquiring subsequent acute respiratory infections.

Prescribing Antibiotics Shortens Telemedicine Visits for Respiratory Tract Infections

Prescribing Antibiotics Shortens Telemedicine Visits for Respiratory Tract Infections

These findings may highlight physician difficulty explaining to patients why antibiotics are not required.

Minimum Inhibitory Concentrations May Predict Risk of Relapse in Tuberculosis

Minimum Inhibitory Concentrations May Predict Risk of Relapse in Tuberculosis

Higher minimum inhibitory concentration values of isoniazid or rifampin are associated with a greater risk of relapse in drug-susceptible tuberculosis than lower MICs.

Protective Role of Pre-F Antibodies Against RSV Acute Respiratory Infection

Protective Role of Pre-F Antibodies Against RSV Acute Respiratory Infection

Serum antibodies against the pre-fusion respiratory syncytial virus fusion protein (pre-F) may be a correlate of protection against RSV acute respiratory infection.

Benefits of Early Azithromycin Therapy in Children With Respiratory Infections

Benefits of Early Azithromycin Therapy in Children With Respiratory Infections

A study recently published in the Journal of Antimicrobial Chemotherapy shows the clinical benefits of early target attainment of azithromycin therapy when treating children with lower respiratory tract infections.

Effect of Respiratory Tract Microbiome on Susceptibility to Viral Infections

Effect of Respiratory Tract Microbiome on Susceptibility to Viral Infections

New data suggest commensal respiratory microbiota play a significant role in susceptibility to viral infection.

Interleukin-8 Enhances Diagnosis of Invasive Aspergillosis in High-Risk Patients

Interleukin-8 Enhances Diagnosis of Invasive Aspergillosis in High-Risk Patients

High serum levels of IL-8 were highly specific and showed high sensitivity when combined with either the BALF, LFD, or BALF Aspergillus PCR, for differentiating probable invasive aspergillosis from cases with no infection.

Tobramycin Efficacy Decreased by Human Airway Mucus

Tobramycin Efficacy Decreased by Human Airway Mucus

Human airway mucus alters the susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin.

Data Support FDA Restrictions on Child Cough and Cold Medicines

Data Support FDA Restrictions on Child Cough and Cold Medicines

New research supports expanded restrictions on opioid-containing cough and cold medications for children.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) deaths in children decreased between 2000 and 2015.

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