The Lancet Respiratory Medicine staged a debate between proponents and opponents of pan-TB regimens to tackle the current suboptimal worldwide management of TB resistance.
Clinicians should consider these findings when using atypical antipsychotics in patients at risk for pneumonia.
Study identifies and validates a simple PCR-based test from accessible blood samples that predicts TB in heterogeneous African populations with intermediate to high TB burdens.
Two novel immune-response clusters have been identified to respiratory syncytial virus, tied to first-, second-year recurrent wheeze.
In the LEAP 2 study (N=738), patients with moderate CABP received either oral lefamulin 600mg every 12 hours for 5 days or oral moxifloxacin 400mg once daily for 7 days.
Provision of assay doesn't result in less antibiotic use for suspected lower respiratory tract infection
Even relatively low-efficacy influenza vaccines can have a high impact, especially with optimal distribution across age groups.
A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.
A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.
Short-term exposure to fine particulate matter is associated with increased health care utilization for acute lower respiratory infection.
Large cavitary lung disease may increase cough frequency that lasts for a longer duration in individuals with tuberculosis.
Control of active tuberculosis (TB) and a major effort to decrease latent TB infection are both necessary to reduce morbidity and achieve TB elimination in the United States.
The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.
Additional studies are needed to investigate whether there are differences between individual fluoroquinolones with respect to the risk for aortic aneurysm.
During the cold and flu season, the use and over-dosing of paracetamol is common, and may partially be driven by higher use of over-the-counter combination medications for the treatment of upper respiratory cold/flu symptoms.
Researchers found increased myocardial infarction rates during the week after Streptococcus pneumoniae and influenza infections.
A 56-year-old man with improved flu-like symptoms, but marked shortness of breath and palpitations, presents to an urgent care center.
Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.
Researchers assessed the relationship between prevention of RSV in preterm infants and the frequency of subsequent wheeze in childhood.
When antibiotics are indicated for the treatment of acute bacterial sinusitis, the Infectious Diseases Society of America evidence-based clinical practice guidelines recommend 5 to 7 days of therapy for patients with a low risk of antibiotic resistance who have a favorable response to initial therapy.
There were declines in mortality from most categories of infectious diseases, with large differences among US counties. However, over this time there was an increase in mortality for diarrheal diseases.
In an attempt to determine if the presence of S aureus could be used as a marker for more severe disease, investigators assessed the relationship between S aureus-positive bronchiectasis infection and pulmonary function, frequency of exacerbations, and hospital admissions.
Childhood measles compounds the association between smoking and midlife airflow obstruction.
The probability of direct transmission of respiratory diseases for passengers on transcontinental US flights not seated in close proximity to an infectious passenger is low.
Children receiving 3 months of once-weekly isoniazid and rifapentine were more likely to complete therapy than those receiving 9 months of daily isoniazid.
All formulations of a respiratory syncytial virus (RSV) candidate vaccine were able to boost RSV antibody titers and their safety profile was similar to the Tdap vaccine.
Middle-aged woman who received a heart transplant 1 year ago because of dilated cardiomyopathy now presents with mild fever and generalized weakness.
The utilization of this tool could prevent severe complications secondary to delayed pneumonia diagnosis and treatment.
Induced hypothermia (target temperature 32°C-34°C) proved harmful with regards to respiratory function and it also prolonged septic shock.
A middle-aged man with no significant medical history presents to the local urgent care center after 3 days of fevers, sore throat, rhinitis, coughing, and myalgia.
Sign Up for Free e-newsletters
Infectious Disease Advisor Articles
- New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians
- Increasing Incidence of Syphilis in People With HIV
- FDA: Possible Risk of Neural Tube Birth Defects With Certain Antiretroviral Agents
- Fungal Infections of the CNS: Diagnostic and Treatment Approaches
- Study Supports Development of a Vaccine for Recurrent Vulvovaginal Candidiasis
- Early Flow Cytometry Predictive of Clinical Deterioration in Sepsis
- Could a New Universal Tuberculosis Regimen Help End the TB Pandemic?
- Hepatitis C Virus Infection Linked to Gut Dysbiosis
- Two Hepatitis C Virus Infection Treatments to Be Discontinued
- Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma