Respiratory

High-Touch Surfaces at Airports Often Covered in Pathogens

High-Touch Surfaces at Airports Often Covered in Pathogens

At least one respiratory virus detected in 10 percent of surface samples at major airport during flu season.

Pediatric Histoplasmosis Most Frequently Manifested as Pulmonary Disease

Pediatric Histoplasmosis Most Frequently Manifested as Pulmonary Disease

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Pediatric histoplasmosis most frequently manifests as pulmonary disease, and the highest diagnostic yields were achieved when multiple diagnostic modalities were used.

Protective Role of Pre-F Antibodies Against RSV Acute Respiratory Infection

Protective Role of Pre-F Antibodies Against RSV Acute Respiratory Infection

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Serum antibodies against the pre-fusion respiratory syncytial virus fusion protein (pre-F) may be a correlate of protection against RSV acute respiratory infection.

Benefits of Early Azithromycin Therapy in Children With Respiratory Infections

Benefits of Early Azithromycin Therapy in Children With Respiratory Infections

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A study recently published in the Journal of Antimicrobial Chemotherapy shows the clinical benefits of early target attainment of azithromycin therapy when treating children with lower respiratory tract infections.

Effect of Respiratory Tract Microbiome on Susceptibility to Viral Infections

Effect of Respiratory Tract Microbiome on Susceptibility to Viral Infections

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New data suggest commensal respiratory microbiota play a significant role in susceptibility to viral infection.

FDA Warns Against Long-Term Azithromycin Use for Some

FDA Warns Against Long-Term Azithromycin Use for Some

The FDA is warning patients with cancers of the blood or lymph nodes who undergo a donor stem cell transplant not to take azithromycin,

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

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Inappropriate antibiotic prescriptions were highest among urgent care facilities (45.7%), with emergency departments (24.6%), medical offices (17.0%), and retail clinics (14.4%) following.

A Pan-Tuberculosis Regimen: The Debate Continues

A Pan-Tuberculosis Regimen: The Debate Continues

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Last month the South Africa National Tuberculosis Program decided to make oral bedaqualine available for all rifampin-resistant TB (RR-TB) in place of — the often more toxic — injectable drugs.

Interleukin-8 Enhances Diagnosis of Invasive Aspergillosis in High-Risk Patients

Interleukin-8 Enhances Diagnosis of Invasive Aspergillosis in High-Risk Patients

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High serum levels of IL-8 were highly specific and showed high sensitivity when combined with either the BALF, LFD, or BALF Aspergillus PCR, for differentiating probable invasive aspergillosis from cases with no infection.

Tobramycin Efficacy Decreased by Human Airway Mucus

Tobramycin Efficacy Decreased by Human Airway Mucus

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Human airway mucus alters the susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin.

Predictors of Influenza Vaccine Acceptance in Inflammatory Rheumatic Diseases

Predictors of Influenza Vaccine Acceptance in Inflammatory Rheumatic Diseases

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A direct recommendation from physicians had the greatest effect on patients' positive vaccination status.

Data Support FDA Restrictions on Child Cough and Cold Medicines

Data Support FDA Restrictions on Child Cough and Cold Medicines

New research supports expanded restrictions on opioid-containing cough and cold medications for children.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) deaths in children decreased between 2000 and 2015.

Community-Acquired Pneumonia In-Hospital Deaths Are Not Indicative of Lapse in Care

Community-Acquired Pneumonia In-Hospital Deaths Are Not Indicative of Lapse in Care

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Most deaths related to community-acquired pneumonia that occurred at tertiary-case hospitals were not preventable.

CDC: Updated Recommendations for Latent TB Infection Treatment

CDC: Updated Recommendations for Latent TB Infection Treatment

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The CDC has issued updated recommendations regarding the use of 3HP for the treatment of latent tuberculosis.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

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Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Priority Review Granted to Novel Oral Influenza Treatment

Priority Review Granted to Novel Oral Influenza Treatment

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Baloxavir marboxil, an investigational, oral treatment for acute uncomplicated influenza in those aged ≥12 years has been granted Priority Review by the FDA.

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

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The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.

Increase in VA Legionnaires' Disease Rates From 2014 to 2016

Increase in VA Legionnaires' Disease Rates From 2014 to 2016

There was an increase in Legionnaires' Disease (LD) from 2014 to 2016.

Mandatory Influenza Vaccination Advised for Healthcare Personnel in VA, Non-VA Hospitals

Mandatory Influenza Vaccination Advised for Healthcare Personnel in VA, Non-VA Hospitals

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A national survey was conducted to assess influenza prevention practices in Veterans Affairs and non-Veterans Affairs hospitals in the United States.

CDC: Invasive MRSA More Likely Among Injection Drug Users

CDC: Invasive MRSA More Likely Among Injection Drug Users

Injection drug users are more than 16-fold more likely to develop invasive methicillin-resistant Staphylococcus aureus infections.

Improving Type-Based Surveillance of Enterovirus and Parechovirus

Improving Type-Based Surveillance of Enterovirus and Parechovirus

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Between 2014 and 2016, a total of 2967 cases of enterovirus and parechovirus were reported to the National Enterovirus Surveillance System in the United States.

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

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The real-world effectiveness of PCV13 vaccine in preventing hospitalization for vaccine-type community-acquired pneumonia was assessed.

Respiratory Pathogens May Increase Asthma Treatment Failure Risk

Respiratory Pathogens May Increase Asthma Treatment Failure Risk

Respiratory pathogens are associated with increased risk of treatment failure in children with asthma exacerbations.

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

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Although clinical presentation was similar in both community-acquired pneumonia and non-pneumonia exacerbations, CRP, glucose, and leukocytes were higher in the former vs the latter.

FDA Issues Final Guidance on Inhalational Anthrax

FDA Issues Final Guidance on Inhalational Anthrax

The FDA has issued final guidance to assist in the development of drugs for the prevention of inhalational anthrax.

Viruses not linked to asthma exacerbation severity

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.

Independent Predictors of Bronchiolitis Mortality After ED Discharge

Independent Predictors of Bronchiolitis Mortality After ED Discharge

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Infants with bronchiolitis and comorbidities plus other predictive factors are at higher risk for death following discharge from the emergency department.

Children Typically Have 14 Simple Infections by Age 3 Years

Children Typically Have 14 Simple Infections by Age 3 Years

Children experience a median of 14 infections during their first three years of life, though there is large variation in incidence.

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

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Early clinical response rates were similar across PORT risk class subgroups in patients with community-acquired bacterial pneumonia when treated with omadacycline or moxifloxacin.

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