Researchers validated the clinical sensitivity of the T2Candida panel for the diagnosis of bloodstream infections caused by the 5 most common pathogenic Candida species.
After hospital discharge for sepsis, the healthcare team should focus on identifying new functional, mental, and cognitive impairments and referring patients to appropriate treatment; reviewing and adjusting long-term medications; and evaluating for treatable conditions that commonly result in hospitalizations.
Patients with septic shock in the intensive care unit undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality compared to placebo treated patients.
Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone infusion, did not have a lower 90-day mortality compared to placebo.
Vaginal microbiota composition is a risk factor for subsequent preterm prelabor rupture of the fetal membranes and is associated with adverse short-term maternal and neonatal outcomes.
Findings indicate the critical role of conservative fluid strategy in the management of patients with complicated influenza.
Use of the SEP-1 Bundle or its hemodynamic interventions is not associated with improved survival in patients with sepsis.
Organ systems where bacterial infections predominate as well as fungal diseases were associated with substantial increases in magnitude among patients with both T1D and T2D, but risks were consistently higher for T1D.
Induced hypothermia (target temperature 32°C-34°C) proved harmful with regards to respiratory function and it also prolonged septic shock.
No moderate- or high-level evidence was found that SEP-1 or its hemodynamic interventions increase survival in septic adults.
Capillary refill time has the potential to predict outcomes in patients with sepsis-related hyperlactatemia.
Higher mortality associated with opioid use in hospitalized patients with sepsis suggests an immunosuppressive effect that could contribute to worse outcomes.
Researchers conducted a systematic review and meta-analysis to assess the effectiveness and safety of short-term vs prolonged infusion of antipseudomonal β-lactams in patients with sepsis.
Adjunctive glucocorticoid therapy in patients with septic shock may reduce the duration of shock.
Study showed that very low birth weight infants exposed to gastric acid inhibitors have significantly increased odds of developing infections, and that the risk increases with each day of exposure.
A study evaluated the association between high-risk antibiotic exposure during hospitalization and subsequent sepsis risk.
Stanford T. Shulman, MD, editorial advisory board member for Infectious Disease Advisor, outlines reasons why IDSA elected not to endorse the 2016 Surviving Sepsis Campaign Guidelines.
Results from this study are novel with respect to the combined use of leukocyte count, procalcitonin, interleukin-6, and paraoxonase-1 activity for mortality prediction.
Prospective studies are needed to determine the incidence of UTI in the NICU population without predisposing UTI factors when fluconazole prophylaxis is administered to examine whether routine urinalysis would still be justified.
Patients with sepsis have a greater long-term risk for seizures.
Identification of premature infants at low risk of early onset sepsis may help guide decisions for initiating and/or discontinuing empirical antibiotic treatments in the first days of life.
Maternal hypertension, intravascular thrombosis, and Gram-negative sepsis were independent risk factors for thrombocytopenia in multivariate analysis.
Addition of previously unconsidered genes from the PERSEVERE model can improve mortality risk stratification for children with septic shock.
The study includes a large number of diverse hospitals which account for approximately 10% of all acute care hospitalizations in the United States in 2014.
Infantile sepsis evaluations vary considerably and could benefit from the development of an updated, standardized guideline.
Sepsis cases among adolescents seen in emergency departments is rare according to a recently published research letter.
Cardiovascular disease risks persist for years after sepsis or pneumonia.
Men who have sepsis or pneumonia have a higher risk of cardiovascular disease.
The quick Sepsis-Related Organ Failure Assessment (qSOFA) clinical tool was superior to SIRS criteria for the evaluation of in-hospital mortality.
A resolution recently adopted by the World Health Organization's World Health Assembly could significantly lower the incidence and impact of sepsis.
Sign Up for Free e-newsletters
Infectious Disease Advisor Articles
- Major Advances on Horizon for Tick-Borne Disease Testing
- Measles Vaccination After Third Dose of DTP Vaccine May Improve Child Survival
- Vegetation Size May Increase Mortality Risk in Infective Endocarditis
- FDA Approves Blood Screens for Tickborne Parasite
- Effect of Vaccine Antigen Exposure in First 23 Months of Life
- Substantial Variation in HIV Diagnoses Among Persons Aged 13 to 29 Years
- Obesity, Older Age, and Pretreatment Cirrhosis Delay Fibrosis Improvements in HCV
- Oseltamivir Does Not Increase Suicide Risk in Pediatric Population
- Hepatitis C Eradication With DAAs Improves Carotid Atherosclerosis
- CDC Reports Number of Noncongenital Zika Virus Cases in the United States