Healthy Microbiome Is Key to Sepsis Management
The authors emphasize that sepsis treatment should be guided by the connection between the microbiota and sepsis outcomes.
Antibiotic Stewardship
Psychiatric Wards Need More Rigorous Infection Prevention Measures
This study determines which psychiatry specific factors contributed to a nosocomial outbreak taking place in a psychiatric department.
Guidance Provided for Antibiotic Stewardship in Pediatrics
ASPs should be established to improve antibiotic prescribing, should include specialists with pediatric expertise.
Alcaligenes faecalis: An Emerging Extensively Drug-Resistant Bacterium
Retrospective analysis was conducted to assess the presence of A faecalis infection, extensively drug-resistant A faecalis infection, and the susceptibility of commonly used antibiotics for the treatment of A faecalis and XDR A faecalis.
Mass Azithromycin Distribution Associated With Antibiotic Resistance
Investigators assessed the effect of mass distribution of azithromycin to preschool children on the gut resistome.
Infectious Diseases Consultation Effectively Reduces Antibiotic Use in Hospitals
Investigators assessed whether a daily service of infectious disease consultation was more effective than weekly consultation to reduce antibiotic use without worsening clinical outcomes.
Oral Beta-Lactams Effective Step-Down Therapy for Bacteremic UTI
Study authors compared clinical cure in patients with E coli bacteremic UTI who were stepped down to oral beta-lactams compared to oral fluoroquinolones.
Assessing the Effect of Antimalarial Drug Shortages in Rheumatic Disease During the COVID-19 Pandemic
The COVID-19 Global Rheumatology Alliance Patient Experience Survey was used to assess the effect of antimalarial drug shortages during the COVID-19 pandemic.
Acute Kidney Injury with Vancomycin, Antipseudomonal Combination Therapy
Investigators assessed the incidence of acute kidney injury in patients requiring vancomycin and antipseudomonal agents, particularly comparing piperacillin-tazobactam vs cefepime in combination with vancomycin.
Review of Antimicrobial Resistance in Human-Derived C Difficile
Metronidazole, vancomycin, fidaxomicin, meropenem, and piperacillin/tazobactam are rarely resistant to Clostridioides (Clostridium) difficile infection, while second-generation fluoroquinolones and clindamycin show highest risk.
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