Efficacy of Lefamulin vs Moxifloxacin for Legionella CABP
Lefamulin appears to be noninferior in safety and efficacy compared with moxifloxicin in the treatment of community-acquired bacterial pneumonia.
Antibiotic Stewardship
DRIP Scoring System Improves Antibiotic Prescription Patterns for Pneumonia
A new scoring system for Drug Resistance in Pneumonia (DRIP) has demonstrated efficacy in improving pneumonia-related prescription trends, including a significant drop in broad-spectrum antibiotic prescriptions.
Comparison of Antibiotic Activity in Complicated UTI From Gram-Negative Bacteria
Ceftazidime-avibactam was highly active against a large collection of gram-negative bacteria isolated from patients with complicated urinary tract infections.
Revised Antimicrobial Policies Needed for Ophthalmic Infections in United Kingdom
Antimicrobial prescribing guidelines and policies should be revised for ophthalmic infections in the United Kingdom.
Customizing Electronic Medical Records May Decrease Antimicrobial Usage
Automating the workflow and tracking an antimicrobial stewardship program by customizing electronic medical records may decrease antimicrobial usage.
Once-Daily Omadacycline Noninferior to Twice-Daily Linezolid for ABSSSI in Adults
Once-daily oral omadacycline was noninferior to twice-daily oral linezolid in adults with acute bacterial skin and skin structure infections.
Millions May Benefit From Treatment to Prevent Active TB
Revised NHANES-based estimate for prevalence of latent TB infection excludes those who report prior tx
Initiating Empirical Treatment for Sepsis Reduces Blood Culture Sensitivity
When empirical antimicrobial therapy is initiated in patients with severe manifestations of sepsis, the sensitivity of blood cultures drawn shortly after treatment initiation is reduced.
Anti-CRE Agents Are Used Less Widely Than Expected After FDA Approval
New antibiotics indicated to treat carbapenem-resistant Enterobacteriaceae infections were prescribed in only 35% of CRE infections.
Suboptimal Adherence to Guidelines for Urine Cultures Orders in Patients With Catheters
Healthcare professionals may inappropriately order urine cultures for patients with catheters, on the basis of subjective signs rather than evidence-based guidelines.
