Effect of Antibiotic Stewardship on Fluoroquinolone Prescribing in Hospital
Hospital-based stewardship interventions were associated with decreased fluoroquinolone prescriptions during hospitalization, but not at discharge.
Antibiotic Stewardship
Procalcitonin-Guided Antibiotic Discontinuation May Increase Survival
Procalcitonin-guided antibiotic discontinuation was linked with greater rates of survival and reduced antibiotic utilization in critically ill individuals.
Inconclusive Results for Antibiotic Treament of Urogenital C trachomatis
More research may be needed comparing antibiotic regimens to treat Chlamydia trachomatis in men and nonpregnant women.
Safety and Efficacy of Lefamulin for Treatment of Community-Acquired Pneumonia
A novel antibiotic, lefamulin, may not be inferior to moxifloxacin in efficacy and safety for the treatment of community-acquired bacterial pneumonia.
New Algorithm Identifies Risks in Nosocomial Pneumonia
A new algorithm can search administrative data for individuals with HAP and VAP, who are at significant risk for carbapenem-resistant infection.
Restrictive OPAT Criteria for Infective Endocarditis May Need Revision
A less restrictive criteria for the use of OPAT for patients with infective endocarditis than current IDSA guidelines was efficacious and safe.
Prolonged Intermittent Renal Replacement Therapy May Result in Suboptimal Colistin Level
Prolonged intermittent renal replacement therapy may eliminate as much as half of the daily dose of colistin in patients who are critically ill.
Ceftaroline Every 8 Hours Noninferior to 12 Hour Dosing
Ceftaroline 600 mg every 8 hours has demonstrated tolerability in individuals with complicated skin and soft tissue infection.
Review Shares Best Practices for Evaluating Penicillin Allergy
Verifying reported allergies necessary to improve outcomes, prevent antibiotic resistance
Bacteria Bystanders Play Important Role in Antibiotic Resistance Development
It is vital to consider the antibiotic exposures of “bystander” pathogens, in addition to the target organism, and consequences on antibiotic resistance.
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