Investigators characterized temporal and spatial variation in the skin microbiota of patients undergoing colorectal surgery and to determine if dysbiosis contributes to surgical site infections.
Study authors compared clinical cure in patients with E coli bacteremic UTI who were stepped down to oral beta-lactams compared to oral fluoroquinolones.
Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.
Researchers compared the efficacy and safety of cefiderocol vs high-dose, extended-infusion meropenem for adults with nosocomial pneumonia.
Investigators evaluated the relationship between delay of meropenem and vaborbactam therapy in patients with gram-negative bacterial infections and negative clinical outcomes.
Double anaerobic therapy with piperacillin/tazobactam plus metronidazole was compared to piperacillin/tazobactam alone to manage patients with intra-abdominal infections.
Investigators assessed the incidence of acute kidney injury in patients requiring vancomycin and antipseudomonal agents, particularly comparing piperacillin-tazobactam vs cefepime in combination with vancomycin.
Study authors sought to determine the effect of antibiotic use and immune checkpoint inhibitors on overall survival, profession-free survival, response rate, and progressive disease rate in cancer patients.
The incidence of acute kidney injury in patients treated with vancomycin outpatient parenteral antimicrobial therapy was assessed, and risk factors for AKI in this population were identified.
The effect of ticagrelor in addition to cefazolin plus ertapenem for the clearance of S aureus bacteremia was assessed in a case study.
