DDW: Antibiotics Increased Risk of Older-Onset Inflammatory Bowel Disease
Use of antibiotics, regardless of class, is associated with an increased risk of older-onset inflammatory bowel disease.
Antibiotics
Risk for Liver Injury Associated With Duration of Tigecycline Treatment
Researchers conducted a retrospective study that assessed risk factors for liver injury among hospitalized patients receiving intravenous tigecycline.
Efficacy of Standard Piperacillin Dosing in Children on Continuous Kidney Replacement Therapy
Researchers assessed the pharmacokinetics of piperacillin to determine whether standard dosing provides adequate exposure in critically ill children receiving continuous kidney replacement therapy.
Antibiotics for Less Than 24 Hours After Orthopedic Surgery Prevents Health Care-Associated Infections
Researchers assessed the effects of discontinuing antimicrobial prophylaxis within 24- vs 48-hours of clean orthopedic surgery for the prevention of health care-associated infections.
Diagnostic Stewardship Reduces Blood Cultures, Antibiotic Use in PICU
In the pediatric intensive care unit, multidisciplinary diagnostic stewardship interventions can reduce blood culture and antibiotic use.
Gram Stain-Guided Antibiotics: Effective, May Combat Spread of Multidrug-Resistant Pathogens
Researchers compared the effect of Gram stain-guided antibiotics with guideline-based antibiotics for the treatment of patients with ventilator-associated pneumonia.
Concerns Raised Over Volume of Antibiotic Prescriptions for Older Adults With COVID-19 at Outpatient Visits
Researchers assessed the rate of inappropriate antibiotic prescriptions among older adults diagnosed with COVID-19 infection at outpatient settings.
Antibiotics Within the Same Class May Not Be Ideal in Combination Therapy for Bloodstream Infections
Researchers assessed the efficacy and interaction between the 4 most common antibiotic combinations for Escherichia coli bloodstream infections.
Recurrent Diabetic Foot Infection Not Associated With Shorter Antibiotic Duration
Researchers assessed whether a shorter duration of antibiotic therapy is associated with an increased risk for recurrent diabetic foot infection.
Stakeholder Involvement Helps Ensure Success of Antibiotic Dispensing Interventions in Low- and Middle-Income Countries
Researchers conducted a systematic review of studies that reported on interventions to increase the rate of appropriate antibiotic dispensing in low- and middle-income countries.
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