Posaconazole Noninferior to Voriconazole for Primary Treatment of Invasive Aspergillosis
Study authors assessed the noninferiority of posaconazole to voriconazole for the primary treatment of invasive aspergillosis.
Antibiotics
Delayed Antibiotic Prescribing Safe for Respiratory Tract Infection
Researchers conducted a systematic review and individual patient data meta-analysis to examine the overall effect of delayed antibiotic prescribing on average symptom severity for patients with respiratory tract infections.
Urinary Tract Infection Prophylaxis Among Older Adults Increase Risks
Study authors examined 186,589 patients with an initial positive urine culture and receiving antibiotics to quantify risks and benefits of UTI prophylaxis in older adults.
Factors Contributing to Eradication of Helicobacter pylori With Vonoprazan, Amoxicillin Therapy
A team of investigators conducted a multicenter, randomized, controlled trial to identify factors related to the eradication of H pylori with dual vonoprazan and amoxicillin as first-line therapy.
Short-Course Antibiotics Noninferior for Pediatric Pneumonia
For the treatment of community-acquired pneumonia, 5 days of antibiotic therapy is noninferior to standard of care.
Fluoroquinolones Associated With Increased Aortic Aneurysm Risk
Study authors assessed aortic aneurysm and dissection risks after fluoroquinolone use in the United States.
Adjunctive Clindamycin in Invasive Group A/B Beta-Hemolytic Streptococcus
The researchers wanted to gather evidence about the efficacy of adding clindamycin to β-lactam antibiotics to treat patients with severe iGAS and those with iNABS infections.
Maternal Antibiotic Use During Pregnancy May Increase Risk of Childhood Asthma
Exposure to maternal antibiotics during pregnancy may be associated with an increased risk of childhood asthma.
Invasive E coli Infections Cause Significant Burden on US Healthcare Systems
Study authors conducted a retrospective, observational study to assess the prevalence and risk of recurrence of extraintestinal invasive E coli infections in the United States.
Previous Infection and Antibiotic Use Linked to Guillain-Barré Syndrome
Danish researchers looked into whether hospital-diagnosed and community-treated infections are important risk factors for GBS by examining the magnitude and duration of associated GBS risk.
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