Researchers conducted a systematic review and meta-analysis to assess outcomes associated with ongoing antibiotic prophylaxis vs discontinuation following surgery.
An interactive, in-person barrier identification and mitigation tool can ensure safe administration of home-based outpatient parenteral antimicrobial therapy.
Patients treated with hydroxychloroquine alone or in combination with azithromycin for pneumonia associated with COVID-19 were found to be at increased risk for corrected QT interval prolongation.
The concern for development of new resistance to central lines coated with antimicrobial combinations was not validated by current clinical and experimental evidence.
Screening for extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) carriage before and personalizing prophylaxis for carriers after elective colorectal surgery reduces the risk of surgical site infections.
Linezolid use in combination therapy is effective and as safe as other firstline treatments for moderate to severe nocardiosis.
Extended-pulsed fidaxomicin regimen for treatment of C difficile infection maintained fidaxomicin stool concentrations above the minimum inhibitory concentration required to inhibit the growth of 90% of organisms for 26 days.
Streptococcus pyogenes strains with mutations in the pbp2x gene may have decreased susceptibility to beta-lactam antibiotics.
For people who have low-risk reaction histories in an inpatient setting, direct oral challenges may be a safe, effective, and less expensive option for penicillin allergy delabeling when compared to penicillin skin testing.
The terms carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant organism (CRO) are inadequate in light of new therapies.
