Updates and Challenges for WHO Antibiotic Targets
Investigators reviewed patterns of antibiotic consumption in each of the WHO Access, Watch, and Reserve (AWaRe) categories over a span of 15 years and documented changes.
Antibiotics
Prior Care Experiences Determine Antibiotic Prescribing for Future Acute Respiratory Illness
One potential driver of high antibiotic prescribing rates for acute respiratory infections is patient’s prior care experiences.
Antibiotics May Reduce Efficacy of Hormonal Contraceptives
The efficacy of hormonal contraceptives may be reduced with use of antibiotics.
Antibiotics Are an Effective Therapy for Most Children With Uncomplicated Appendicitis
Antibiotic therapy was found to shorten recovery time for pediatric patients with uncomplicated appendicitis, thereby avoiding surgery.
Number of Antibiotics Used, Neoplasia History Associated With Recurrent C diff Infection
Patients who received more than 3 types of antibiotics in the year prior to C diff onset were more likely to experience a reoccurrence of C diff infection.
ESBL-Producing Enterobacterales Not a Causative Pathogen for Majority of Infections in ESBL-Producing Enterobacterales Carriers
Researchers investigated the relative proportions of ESBL-producing Enterobacterales vs non-ESBL-producing Enterobacterales infections in patients with ESBL-producing Enterobacterales colonization.
Meta-Analysis Supports WHO-Recommended Discontinuation of Antibiotic Prophylaxis After Surgery
Researchers conducted a systematic review and meta-analysis to assess outcomes associated with ongoing antibiotic prophylaxis vs discontinuation following surgery.
Strategies for Safe Home-Based Outpatient Parenteral Antimicrobial Therapy
An interactive, in-person barrier identification and mitigation tool can ensure safe administration of home-based outpatient parenteral antimicrobial therapy.
Hydroxychloroquine With or Without Azythromycin for COVID-19 Treatment Associated With Increased Risk for QTc Prolongation
Patients treated with hydroxychloroquine alone or in combination with azithromycin for pneumonia associated with COVID-19 were found to be at increased risk for corrected QT interval prolongation.
Developing New Antimicrobial Resistance From Medical Devices Is Rare
The concern for development of new resistance to central lines coated with antimicrobial combinations was not validated by current clinical and experimental evidence.
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