Dual Therapy With Rilpivirine and Boosted Darunavir Is Effective in PLWHIV
Rilpivirine plus boosted-darunavir dual therapy may be effective and safe in patients with advanced HIV.
Antiretrovirals
Predictors of Doravirine Resistance After Exposure to NNRTIs
Doravirine resistance is uncommon in people with HIV who have been treated with non-nucleoside reverse transcriptase inhibitors.
First Two-Drug Regimen Approved for HIV-1 Treatment
The FDA has announced the approval of Dovato for adults with HIV-1 who have not been previously treated with antiretroviral medication.
Dolutegravir Feasible for HIV Treatment in Women of Childbearing Age
Dolutegravir should be considered for ART in treating HIV in women of childbearing potential.
Changing Epidemiology of Acute HCV Infections in MSM in France
The epidemiology of acute hepatitis C virus infections, spreading from MSM who have to MSM who do not have HIV through sharing of high-risk activities such as chemsex and traumatic sexual practices.
National Sample Shows 40% of Patients Adhere to Full PrEP Schedule
Results showed substantial nonpersistence of PrEP for HIV prevention in both year 1 and 2, with only 40% of users adhering for the entire 2-year period.
Persistent Low-Level Viremia May Increase Virologic Failure Risk in PLWHIV
In people with HIV, persistent low-level viremia may be an independent predictor of virologic failure and needs further investigation.
Increased Transmitted Drug-Resistance Mutations of Non-B HIV Subtypes
Prevalence of transmitted-drug-resistance-associated mutations were stable from 2010-2011 to 2015-2016, but there was an increase in HIV non-B subtypes.
Lactoferrin Ineffective for Patients with HIV Receiving ART
Recombinant human-lactoferrin treatment in PLWHIV receiving ART was not associated with significant improvements in inflammation or immune activation.
DISCOVER Study Finds New Dual NRTI Pill Noninferior to Current Combo
A study shows Descovy for PrEP demonstrated that the treatment was non-inferior to Truvada for HIV prevention.
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