Cerebrospinal Fluid Biomarkers for CNS Infections
The tryptophan-kynurenine-NAD+ (TK) pathway may provide accurate cerebrospinal fluid biomarkers.
Bacterial Infections
Hospital-Onset MRSA Decreased From 2002 to 2015
Staphylococcus aureus infections are still a concern in the United States, despite a decline seen in hospital-onset MRSA infections since 2005.
Early vs Delayed Cholecystectomy in Acute Cholangitis/Acute Cholecystitis
No significant differences in surgical complication risk were seen in early or delayed cholecystectomy for acute cholangitis and acute cholecystitis.
Drug-Resistant Salmonella Typhi Cases in Travelers Between Pakistan-US
A large outbreak of extensively drug-resistant typhoid fever in Pakistan during 2016-2018 resulted in 5 travel-related cases in the United States.
Infection and Infarction: Cause and Effect?
Investigators sought to confirm long-standing hypotheses that acute infections can lead to myocardial infarction.
CP101 Designated Breakthrough Tx for Recurrent C difficile Infection
The FDA has granted Breakthrough Therapy designation to CP101 for the treatment of patients with recurrent Clostridium difficile.
FDA to Review 2 Antibacterial Agents for Potentially Life-Threatening Infections
Both filings have been granted Priority Review by the Agency.
Infection Control Guidelines in the OR and Anesthesia Work Area
SHEA guideline reflects the potential for clinically significant cross transmission in the intraoperative environment.
Worse Outcomes in Community-Acquired Pneumonia Linked to Higher FGF21 Levels
Patients diagnosed with community-acquired pneumonia with higher levels of fibroblast growth factor-21 may have higher mortality rates and longer hospitalizations.
Bacterial Pneumonia-Complicating Influenza: Risks, Morbidity, and Mortality
Diagnosing coinfection in pneumonia can be challenging because of timing of the sample collection and false-negative results when the viruses replicate in the lower respiratory tract.
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