APEKS-NP: Cefiderocol Non-Inferior to Meropenem for Nosocomial, Gram-Negative Pneumonia
Researchers compared the efficacy and safety of cefiderocol vs high-dose, extended-infusion meropenem for adults with nosocomial pneumonia.
Researchers compared the efficacy and safety of cefiderocol vs high-dose, extended-infusion meropenem for adults with nosocomial pneumonia.
Study authors compared characteristics of moderate to severe diarrhea between children with culture positive Shigella and culture-negative, qPCR-attributable Shigella and derived a new clinical severity score.
Investigators evaluated the relationship between delay of meropenem and vaborbactam therapy in patients with gram-negative bacterial infections and negative clinical outcomes.
Double anaerobic therapy with piperacillin/tazobactam plus metronidazole was compared to piperacillin/tazobactam alone to manage patients with intra-abdominal infections.
Study authors assessed the prevalence of Elizabethkingia, healthcare settings involved, positive culture sites, and mitigation measures to prevent outbreak.
The effect of ticagrelor in addition to cefazolin plus ertapenem for the clearance of S aureus bacteremia was assessed in a case study.
The effect of appropriate antimicrobial therapy on 14-day mortality in patients severely ill with Acinetobacter baumannii bacteremic pneumonia was assessed, taking risk factors, patient demographics, and clinical characteristics into account.
Study authors assessed the association between mortality and age, history of cardiac surgery, and other risk factors in patients undergoing surgery for infective endocarditis.
Researchers performed a systematic review to identify cases of infection-induced antimyeloperoxidase ANCA-associated vasculitis.
A global consensus meeting was convened to go over current evidence and knowledge gaps and propose collaborative studies on population-wide screening and eradication of Helicobacter pylori for the prevention of gastric cancer (GC).