Toenail Onychomycosis: Treatment Options Evaluated
A total of 26 RCTs with 8136 patients were included in this network meta analysis.
Fungal Infections
Trends in Histoplasma-Associated Immune Reconstitution Inflammatory Syndrome
Although incidence of histoplasma-associated immune reconstitution inflammatory syndrome is low, it still generates significant morbidity in people living with HIV.
Efficacy Evaluation for Initial Maintenance Therapy in Chronic Pulmonary Aspergillosis
Oral voriconazole may be more effective than oral itraconazole for initial maintenance therapy in patients with chronic pulmonary aspergillosis, according to a study published in Clinical Infectious Diseases.1 Currently, there are 4 oral anti-Aspergillus agents available (itraconazole, voriconazole, posaconazole, and isavuconazole) and while various studies have evaluated treatments for chronic pulmonary aspergillosis with itraconazole and…
CDC: Candida auris Has Sickened 600 Americans
Candida auris can survive on surfaces after routine cleaning and is often drug-resistant
Quantifying Adherence to Mucormycosis Treatment Guidelines in Patients With Hematologic Malignancies
Adhering to mucormycosis treatment guidelines may be difficult for physicians because of the complexity of the disease.
Prenatal Fluconazole Exposure Increases Neonatal Risks
Maternal exposure to fluconazole during pregnancy may increase the risk for spontaneous abortion.
Voriconazole-Resistant Invasive Aspergillosis Associated With Higher Mortality
Patients with voriconazole-resistant invasive aspergillosis have a higher mortality rate compared with patients with voriconazole-susceptible infection.
Isavuconazole Not Noninferior to Caspofungin for Invasive Candida Infections
Isavuconazole did not demonstrate noninferiority compared with caspofungin in the primary treatment of proven candidemia or invasive candidiasis.
Identification and Control of Candida Auris Outbreak in a Hospital ICU
A recent outbreak of Candida auris in an ICU of the Oxford University Hospitals was determined to be primarily linked to reusable temperature probes.
Many Linens Delivered To US Hospitals Contaminated With Mucorales Mold
A recent microbiological surveillance study found that >10% of linens tested positive for the fungi Mucorales at 20% of the hospitals included in the study.
