Antifungal Prophylaxis Reduces Mortality in Lung Transplantation
Lung transplant recipients who were given antifungal medications prophylactically to prevent invasive fungal infections had lower rates of mortality.
Fungal Infections
Ibrexafungerp NDA for Vulvovaginal Candidiasis Submitted for Review
Ibrexafungerp is an investigational oral antifungal agent representing a novel therapeutic class of structurally-distinct glucan synthase inhibitors known as triterpenoids.
Public Awareness Low for Invasive Fungal Diseases
The Centers for Disease Control and Prevention conducted a study to assess public familiarity of invasive fungal infections.
Invasive Aspergillosis Superinfection Possible in Symptomatic COVID-19
Critically ill patients hospitalized with COVID-19 — particularly those who develop ARDS — may also experience an opportunistic aspergillosis superinfection.
Risk-Adapted Therapy Prevents Fungal Infections in Childhood Leukemia
Risk-adapted therapy effectively prevents fungal infections and reduces neurotoxicity in children with leukemia.
Psoriasis, Fungal Infections Common in Patients With COVID-19
A study identifies the most common skin disorders in patients diagnosed with COVID-19 infection before and during the pandemic.
Terbinafine, Fluconazole, and Itraconazole for Dermatophyte Toenail Onychomycosis
A novel study used network meta-analysis to compare pulse and continuous systemic therapies for toenail onychomycosis.
Update on Efficacy of Treatments for Cutaneous Candidiasis
A review finds that fluconazole is the only commercially available evidence-based option for systemic treatment of cutaneous candidiasis.
Olorofim Receives Breakthrough Therapy Designation for Invasive Fungal Infections
The FDA has granted Breakthrough Therapy designation to olorofim for the treatment of invasive mold infections.
Oral Ibrexafungerp Effective in Vulvovaginal Candidiasis Trial
Scynexis announced positive topline results from the phase 3 VANISH 303 trial of ibrexafungerp for the treatment of vulvovaginal candidiasis (VVC) in women.
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