Invasive Aspergillosis Superinfection Possible in Symptomatic COVID-19
Critically ill patients hospitalized with COVID-19 — particularly those who develop ARDS — may also experience an opportunistic aspergillosis superinfection.
Fungal Infections
Risk-Adapted Therapy Prevents Fungal Infections in Childhood Leukemia
Risk-adapted therapy effectively prevents fungal infections and reduces neurotoxicity in children with leukemia.
Psoriasis, Fungal Infections Common in Patients With COVID-19
A study identifies the most common skin disorders in patients diagnosed with COVID-19 infection before and during the pandemic.
Terbinafine, Fluconazole, and Itraconazole for Dermatophyte Toenail Onychomycosis
A novel study used network meta-analysis to compare pulse and continuous systemic therapies for toenail onychomycosis.
Update on Efficacy of Treatments for Cutaneous Candidiasis
A review finds that fluconazole is the only commercially available evidence-based option for systemic treatment of cutaneous candidiasis.
Olorofim Receives Breakthrough Therapy Designation for Invasive Fungal Infections
The FDA has granted Breakthrough Therapy designation to olorofim for the treatment of invasive mold infections.
Oral Ibrexafungerp Effective in Vulvovaginal Candidiasis Trial
Scynexis announced positive topline results from the phase 3 VANISH 303 trial of ibrexafungerp for the treatment of vulvovaginal candidiasis (VVC) in women.
Higher Frequency of C albicans After Root Canals in Patients With Type 2 Diabetes
Patients with a long-term history of type 2 diabetes mellitus (T2DM) carried Candida albicans in their dental root canals more frequently when they have a primary endodontic infection.
Oral Amphotericin B Formulation Gets Orphan Drug Status for Cryptococcosis
The Food and Drug Administration (FDA) has granted Orphan Drug designation to MAT2203 (Matinas BioPharma) for the treatment of cryptococcosis.
Novel Antifungal Gains Fast Track Designation for Seven Indications
The FDA has granted Fast Track designations to both the oral and intravenous formulations of fosmanogepix for 7 antifungal indications.
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