FDA: Sotrovimab No Longer Authorized to Treat COVID-19 in Any US Region
As of April 5, 2022, CDC Nowcast data reported that the BA.2 subvariant accounted for more than 50% of cases in all US states and territories.
Genitourinary
Oral Tebipenem Effectively Treats Complicated UTI, Pyelonephritis
Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales.
High-Risk HPV Testing vs Cytology to Prevent Cervical Cancer in Women With HIV
Researchers conducted a study that compared an HPV test-and-treat strategy with cytology-based screening on the risk of developing cervical cancer among women with HIV infection.
HPV Vaccination May Be Cutting Cervical Cancer Rates
Might be too soon to tell impact on oropharyngeal and anal cancers
Cefepime-Taniborbactam Bests Meropenem in Complicated UTI Trial
The phase 3 CERTAIN-1 study compared the efficacy and safety of cefepime-taniborbactam to meropenem in 661 adults with cUTI.
MV140 Vaccine May Prevent Recurrent Urinary Tract Infections
MV140 is a sublingual vaccine of whole-cell inactivated bacteria that may be an alternative to frequent antibiotics for recurrent urinary tract infections.
Antibiotic Stewardship Increases Use of Guideline-Concordant Antibiotics for UTI
Researchers conducted a study to assess the effect of an antibiotic stewardship program on the use of appropriate antibiotic therapy among patients with urinary tract infections in the ED.
Tebipenem HBr Gets Priority Review for Oral Treatment of Complicated UTI
The application includes data from the phase 3 ADAPT-PO trial, which evaluated the efficacy and safety of tebipenem HBr in 868 adults with cUTI or acute pyelonephritis.
Transmission Patterns of Chlamydia and Gonorrhea in Men Who Have Sex With Men
Researchers conducted a study that compared the prevalence of single vs multisite Chlamydia trachomatis or Neisseria gonorrhea infections among men who have sex with men.
Clinical, Behavioral Characteristics of Women With Lactobacillus iners- Dominated Vaginal Microbiota
Study finds that information on unprotected intercourse practices, number of sexual partners, and education level may help identify women with Lactobacillus iners-dominated vaginal microbiota.
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