Hepatitis Archives - Infectious Disease Advisor

Besifovir Dipivoxil Maleate Effective, Safe for Long-Term Treatment of Chronic Hepatitis B

By

Emily Pond

June 11, 2020

Study data supports the long-term efficacy and safety of besifovir dipivoxil maleate (BSV) for the treatment of chronic hepatitis B (CHB).

Hepatitis

Universal Testing May Help Identify HCV in Pediatric Population

By

Zahra Masoud

April 24, 2020

New polices, including testing for hepatitis C virus (HCV) during pregnancy, may increase HCV identification in the pediatric population by addressing gaps in maternal HCV testing.

PCT manifests when hepatic UROD activity is <20% of normal.1 As porphyrins accumulate in the liver, they are transported to the skin, leading to phototoxicity as light exposure causes the porphyrins to release photons.1 Subsequently, patients develop blisters on sun-exposed areas of their skin, particularly the hands, face, neck, and forearms. These areas are also prone to blisters and peeling after mild trauma. When the lesions scar, they may resemble systemic scleroderma. In some cases, lesions become painful. Patients may also have abnormal hair growth, skin thickening, and hypopigmentation. PCT is diagnosed when elevated porphyrins are detected in the plasma. Urine and fecal studies can confirm the diagnosis when they show similarly elevated porphyrin levels, with urine typically showing excess uroporphyrin and 7-carboxylate porphyrin and feces showing excess isocoproporphyrin.6 Patients with a PCT diagnosis should be tested for HCV if their status is unknown. Photo Credit: Dr Harout Tanielian/Science Source.

Hepatitis

Effects of Sustained Virologic Response to HCV Therapy on Autoimmune Disease Incidence

By

Bradley van Paridon

April 16, 2020

Patients with chronic hepatitis C (HCV) achieving sustained virologic response to pegylated interferon plus ribavirin therapy did not exhibit an effect on the incidence of systemic lupus erythematosus (SLE) or rheumatoid arthritis.

Hepatitis

USPSTF Updates HCV Screening Recommendation to Include Adults Aged 18 to 79 Years

By

Sweta Gupta

April 10, 2020

The United States Preventive Services Task Force now recommends screening for hepatitis C virus infection in all asymptomatic adults.

CROI 2020

Hepatic Steatosis in People With HIV, People who Use Intravenous Drugs

By

Infectious Disease Advisor Contributing Writer

March 25, 2020

Patients with HIV and those with a history of intravenous drug use may have significantly higher rates of hepatic steatosis, according to research results presented at the virtual Conference on Retroviruses and Opportunistic Infections, held from March 8 to 11, 2020. Two groups of researchers examined the role of hepatic steatosis across these patient populations.…

Hepatitis B is a serious disease that attacks the liver. Approximately 95% of new HB infections occur among adults and unvaccinated adults which behavior risk behaviors. Encourage all patients to get vaccinated for Hepatitis B.

Hepatitis Advisor

Hepatitis B Exposure Risk, Prevalence in the US Adult Homeless Population

By

Bradley van Paridon

March 23, 2020

Hepatitis B virus prevalence was 7 to 10 times higher in a homeless population of Los Angeles compared to the general population of the United States.

Hepatitis Advisor

Hepatocellular Carcinoma Prediction Beyond Year 5 of Therapy in Chronic Hepatitis B

By

Virginia A. Schad, PharmD, RPh

March 20, 2020

A study identifies risk factors for hepatocellular carcinoma (HCC) after the first 5 years of receiving antiviral therapy in white patients with chronic hepatitis B.

Hepatitis

USPSTF Recommends Screening All Adults for Hepatitis C Virus

March 6, 2020

The USPSTF recommends screening for hepatitis C virus infection in all adults.

Hepatitis

Hepatitis B Vaccination Booster Dose After 18 Years Maintains Long-Term Protection

By

Virginia A. Schad, PharmD, RPh

March 2, 2020

Primary vaccination against hepatitis B virus (HBV) at birth may not provide adequate lifelong antibody levels, but a booster vaccine at age 18 years reinforces antibody levels for at least 4 more years.

Hepatitis

Elevated Fatty Liver Index Increases Mortality Risk in Patients With HIV/HCV

By

Virginia A. Schad, PharmD, RPh

February 25, 2020

An elevated fatty liver index appears to be a risk factor for all-cause mortality in patients coinfected with HIV and hepatitis C virus.